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Journal Abstract Search

260 related items for PubMed ID: 9569237

  • 1. Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema.
    Elliott PR, Bilton D, Lomas DA.
    Am J Respir Cell Mol Biol; 1998 May; 18(5):670-4. PubMed ID: 9569237
    [Abstract] [Full Text] [Related]

  • 2. Hypersensitive mousetraps, alpha1-antitrypsin deficiency and dementia.
    Lomas DA, Lourbakos A, Cumming SA, Belorgey D.
    Biochem Soc Trans; 2002 Apr; 30(2):89-92. PubMed ID: 12023831
    [Abstract] [Full Text] [Related]

  • 3. Cleaved antitrypsin polymers at atomic resolution.
    Dunstone MA, Dai W, Whisstock JC, Rossjohn J, Pike RN, Feil SC, Le Bonniec BF, Parker MW, Bottomley SP.
    Protein Sci; 2000 Feb; 9(2):417-20. PubMed ID: 10716194
    [Abstract] [Full Text] [Related]

  • 4. Loop-sheet polymerization: the mechanism of alpha1-antitrypsin deficiency.
    Lomas DA.
    Respir Med; 2000 Aug; 94 Suppl C():S3-6. PubMed ID: 10954247
    [Abstract] [Full Text] [Related]

  • 5. The mechanism of Z alpha 1-antitrypsin accumulation in the liver.
    Lomas DA, Evans DL, Finch JT, Carrell RW.
    Nature; 1992 Jun 18; 357(6379):605-7. PubMed ID: 1608473
    [Abstract] [Full Text] [Related]

  • 6. Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo.
    Mahadeva R, Atkinson C, Li Z, Stewart S, Janciauskiene S, Kelley DG, Parmar J, Pitman R, Shapiro SD, Lomas DA.
    Am J Pathol; 2005 Feb 18; 166(2):377-86. PubMed ID: 15681822
    [Abstract] [Full Text] [Related]

  • 7. Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin.
    Janciauskiene S, Eriksson S, Callea F, Mallya M, Zhou A, Seyama K, Hata S, Lomas DA.
    Hepatology; 2004 Nov 18; 40(5):1203-10. PubMed ID: 15486938
    [Abstract] [Full Text] [Related]

  • 8. Prevention of polymerization of M and Z alpha1-Antitrypsin (alpha1-AT) with trimethylamine N-oxide. Implications for the treatment of alpha1-at deficiency.
    Devlin GL, Parfrey H, Tew DJ, Lomas DA, Bottomley SP.
    Am J Respir Cell Mol Biol; 2001 Jun 18; 24(6):727-32. PubMed ID: 11415938
    [Abstract] [Full Text] [Related]

  • 9. Molecular pathogenesis of alpha-1-antitrypsin deficiency.
    Duvoix A, Roussel BD, Lomas DA.
    Rev Mal Respir; 2014 Dec 18; 31(10):992-1002. PubMed ID: 25442121
    [Abstract] [Full Text] [Related]

  • 10. Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
    Crowther DC, Belorgey D, Miranda E, Kinghorn KJ, Sharp LK, Lomas DA.
    Eur J Hum Genet; 2004 Mar 18; 12(3):167-72. PubMed ID: 14694355
    [Abstract] [Full Text] [Related]

  • 11. New insights into the structural basis of alpha 1-antitrypsin deficiency.
    Lomas DA.
    QJM; 1996 Nov 18; 89(11):807-12. PubMed ID: 8977959
    [Abstract] [Full Text] [Related]

  • 12. Alpha(1)-antitrypsin deficiency, liver disease and emphysema.
    Parfrey H, Mahadeva R, Lomas DA.
    Int J Biochem Cell Biol; 2003 Jul 18; 35(7):1009-14. PubMed ID: 12672469
    [Abstract] [Full Text] [Related]

  • 13. Loop-sheet polymerization: the structural basis of Z alpha 1-antitrypsin accumulation in the liver.
    Lomas DA.
    Clin Sci (Lond); 1994 May 18; 86(5):489-95. PubMed ID: 8033502
    [Abstract] [Full Text] [Related]

  • 14. Oxidation of Z α1-antitrypsin by cigarette smoke induces polymerization: a novel mechanism of early-onset emphysema.
    Alam S, Li Z, Janciauskiene S, Mahadeva R.
    Am J Respir Cell Mol Biol; 2011 Aug 18; 45(2):261-9. PubMed ID: 20971880
    [Abstract] [Full Text] [Related]

  • 15. Inhibiting polymerization: new therapeutic strategies for Z alpha1-antitrypsin-related emphysema.
    Parfrey H, Dafforn TR, Belorgey D, Lomas DA, Mahadeva R.
    Am J Respir Cell Mol Biol; 2004 Aug 18; 31(2):133-9. PubMed ID: 15016619
    [Abstract] [Full Text] [Related]

  • 16. alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization.
    Lomas DA, Elliott PR, Sidhar SK, Foreman RC, Finch JT, Cox DW, Whisstock JC, Carrell RW.
    J Biol Chem; 1995 Jul 14; 270(28):16864-70. PubMed ID: 7622502
    [Abstract] [Full Text] [Related]

  • 17. Polymers of alpha(1)-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema.
    Parmar JS, Mahadeva R, Reed BJ, Farahi N, Cadwallader KA, Keogan MT, Bilton D, Chilvers ER, Lomas DA.
    Am J Respir Cell Mol Biol; 2002 Jun 14; 26(6):723-30. PubMed ID: 12034572
    [Abstract] [Full Text] [Related]

  • 18. Commercial plasma alpha1-antitrypsin (Prolastin) contains a conformationally inactive, latent component.
    Lomas DA, Elliott PR, Carrell RW.
    Eur Respir J; 1997 Mar 14; 10(3):672-5. PubMed ID: 9073003
    [Abstract] [Full Text] [Related]

  • 19. Molecular Mechanism of Z α1-Antitrypsin Deficiency.
    Huang X, Zheng Y, Zhang F, Wei Z, Wang Y, Carrell RW, Read RJ, Chen GQ, Zhou A.
    J Biol Chem; 2016 Jul 22; 291(30):15674-86. PubMed ID: 27246852
    [Abstract] [Full Text] [Related]

  • 20. Conformational changes in serpins and the mechanism of alpha 1-antitrypsin deficiency.
    Carrell RW, Whisstock J, Lomas DA.
    Am J Respir Crit Care Med; 1994 Dec 22; 150(6 Pt 2):S171-5. PubMed ID: 7952655
    [Abstract] [Full Text] [Related]

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