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Journal Abstract Search

180 related items for PubMed ID: 9572880

  • 1. 1'-Benzyl-3,4-dihydrospiro[2H-1- benzothiopyran-2,4'-piperidine] (spipethiane), a potent and highly selective sigma1 ligand.
    Quaglia W, Giannella M, Piergentili A, Pigini M, Brasili L, Di Toro R, Rossetti L, Spampinato S, Melchiorre C.
    J Med Chem; 1998 May 07; 41(10):1557-60. PubMed ID: 9572880
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  • 5. Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1.
    Maier CA, Wünsch B.
    J Med Chem; 2002 Jan 17; 45(2):438-48. PubMed ID: 11784148
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  • 6. Novel highly potent and selective sigma 1 receptor antagonists related to spipethiane.
    Piergentili A, Amantini C, Del Bello F, Giannella M, Mattioli L, Palmery M, Perfumi M, Pigini M, Santoni G, Tucci P, Zotti M, Quaglia W.
    J Med Chem; 2010 Feb 11; 53(3):1261-9. PubMed ID: 20067271
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  • 7. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
    Huang Y, Hammond PS, Whirrett BR, Kuhner RJ, Wu L, Childers SR, Mach RH.
    J Med Chem; 1998 Jun 18; 41(13):2361-70. PubMed ID: 9632369
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  • 8. Thiophene bioisosteres of spirocyclic sigma receptor ligands. 1. N-substituted spiro[piperidine-4,4'-thieno[3,2-c]pyrans].
    Oberdorf C, Schepmann D, Vela JM, Diaz JL, Holenz J, Wünsch B.
    J Med Chem; 2008 Oct 23; 51(20):6531-7. PubMed ID: 18816044
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  • 9. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
    Berardi F, Santoro S, Perrone R, Tortorella V, Govoni S, Lucchi L.
    J Med Chem; 1998 Oct 08; 41(21):3940-7. PubMed ID: 9767631
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  • 10. Novel sigma receptor ligands. Part 2. SAR of spiro[[2]benzopyran-1,4'-piperidines] and spiro[[2]benzofuran-1,4'-piperidines] with carbon substituents in position 3.
    Maier CA, Wünsch B.
    J Med Chem; 2002 Oct 24; 45(22):4923-30. PubMed ID: 12383018
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  • 11. Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.
    Costantino L, Gandolfi F, Sorbi C, Franchini S, Prezzavento O, Vittorio F, Ronsisvalle G, Leonardi A, Poggesi E, Brasili L.
    J Med Chem; 2005 Jan 13; 48(1):266-73. PubMed ID: 15634021
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  • 12. Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.
    Suzuki T, Moriya M, Sakamoto T, Suga T, Kishino H, Takahashi H, Ishikawa M, Nagai K, Imai Y, Sekino E, Ito M, Iwaasa H, Ishihara A, Tokita S, Kanatani A, Sato N, Fukami T.
    Bioorg Med Chem Lett; 2009 Jun 01; 19(11):3072-7. PubMed ID: 19403308
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  • 13. Oxa-Pictet-Spengler reaction as key step in the synthesis of novel σ receptor ligands with 2-benzopyran structure.
    Knappmann I, Schepmann D, Wünsch B.
    Bioorg Med Chem; 2016 Sep 15; 24(18):4045-4055. PubMed ID: 27396684
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  • 14. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
    Berardi F, Giudice G, Perrone R, Tortorella V, Govoni S, Lucchi L.
    J Med Chem; 1996 Oct 11; 39(21):4255-60. PubMed ID: 8863803
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  • 16. Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites.
    Berardi F, Loiodice F, Fracchiolla G, Colabufo NA, Perrone R, Tortorella V.
    J Med Chem; 2003 May 22; 46(11):2117-24. PubMed ID: 12747784
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  • 17. Synthesis of spirocyclic sigma1 receptor ligands as potential PET radiotracers, structure-affinity relationships and in vitro metabolic stability.
    Grosse Maestrup E, Wiese C, Schepmann D, Hiller A, Fischer S, Scheunemann M, Brust P, Wünsch B.
    Bioorg Med Chem; 2009 May 15; 17(10):3630-41. PubMed ID: 19394833
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  • 18. Design, synthesis and pharmacological evaluation of spirocyclic σ(1) receptor ligands with exocyclic amino moiety (increased distance 1).
    Rack E, Fröhlich R, Schepmann D, Wünsch B.
    Bioorg Med Chem; 2011 May 15; 19(10):3141-51. PubMed ID: 21531141
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