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Journal Abstract Search

174 related items for PubMed ID: 9572885

  • 1. Novel and selective 5-HT2C/2B receptor antagonists as potential anxiolytic agents: synthesis, quantitative structure-activity relationships, and molecular modeling of substituted 1-(3-pyridylcarbamoyl)indolines.
    Bromidge SM, Dabbs S, Davies DT, Duckworth DM, Forbes IT, Ham P, Jones GE, King FD, Saunders DV, Starr S, Thewlis KM, Wyman PA, Blaney FE, Naylor CB, Bailey F, Blackburn TP, Holland V, Kennett GA, Riley GJ, Wood MD.
    J Med Chem; 1998 May 07; 41(10):1598-612. PubMed ID: 9572885
    [Abstract] [Full Text] [Related]

  • 2. Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent.
    Bromidge SM, Dabbs S, Davies DT, Davies S, Duckworth DM, Forbes IT, Gaster LM, Ham P, Jones GE, King FD, Mulholland KR, Saunders DV, Wyman PA, Blaney FE, Clarke SE, Blackburn TP, Holland V, Kennett GA, Lightowler S, Middlemiss DN, Trail B, Riley GJ, Wood MD.
    J Med Chem; 2000 Mar 23; 43(6):1123-34. PubMed ID: 10737744
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  • 3. 1-[2-[(Heteroaryloxy)heteroaryl]carbamoyl]indolines: novel and selective 5-HT2C receptor inverse agonists with potential as antidepressant/anxiolytic agents.
    Bromidge SM, Dabbs S, Davies S, Duckworth DM, Forbes IT, Jones GE, Jones J, King FD, Saunders DV, Blackburn TP, Holland V, Kennett GA, Lightowler S, Middlemiss DN, Riley GJ, Trail B, Wood MD.
    Bioorg Med Chem Lett; 2000 Aug 21; 10(16):1863-6. PubMed ID: 10969986
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  • 6. 5-HT2C antagonists based on fused heterotricyclic templates: design, synthesis and biological evaluation.
    Hamprecht D, Micheli F, Tedesco G, Donati D, Petrone M, Terreni S, Wood M.
    Bioorg Med Chem Lett; 2007 Jan 15; 17(2):424-7. PubMed ID: 17079142
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  • 8. Modification of the structure of 4, 6-disubstituted 2-(4-alkyl-1-piperazinyl)pyridines: synthesis and their 5-HT2A receptor activity.
    Paluchowska MH, Bojarski AJ, Bugno R, Charakchieva-Minol S, Wesołowska A.
    Arch Pharm (Weinheim); 2003 Apr 15; 336(2):104-10. PubMed ID: 12761763
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  • 9. Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B (5HT2B) contractile receptor in the rat stomach fundus.
    Audia JE, Evrard DA, Murdoch GR, Droste JJ, Nissen JS, Schenck KW, Fludzinski P, Lucaites VL, Nelson DL, Cohen ML.
    J Med Chem; 1996 Jul 05; 39(14):2773-80. PubMed ID: 8709108
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  • 11. 1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists.
    Bromidge SM, Davies S, Duckworth DM, Forbes IT, Jones GE, Jones J, King FD, Blackburn TP, Holland V, Kennett GA, Lightowler S, Middlemiss DN, Riley GJ, Trail B, Wood MD.
    Bioorg Med Chem Lett; 2000 Aug 21; 10(16):1867-70. PubMed ID: 10969987
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  • 13. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding.
    Metwally KA, Dukat M, Egan CT, Smith C, DuPre A, Gauthier CB, Herrick-Davis K, Teitler M, Glennon RA.
    J Med Chem; 1998 Dec 03; 41(25):5084-93. PubMed ID: 9836624
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  • 15. Isoindolone derivatives, a new class of 5-HT2C antagonists: synthesis and biological evaluation.
    Hamprecht D, Micheli F, Tedesco G, Checchia A, Donati D, Petrone M, Terreni S, Wood M.
    Bioorg Med Chem Lett; 2007 Jan 15; 17(2):428-33. PubMed ID: 17074479
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  • 17. 5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential.
    Martin JR, Bös M, Jenck F, Moreau J, Mutel V, Sleight AJ, Wichmann J, Andrews JS, Berendsen HH, Broekkamp CL, Ruigt GS, Köhler C, Delft AM.
    J Pharmacol Exp Ther; 1998 Aug 15; 286(2):913-24. PubMed ID: 9694950
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