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Journal Abstract Search

131 related items for PubMed ID: 9575348

  • 1. In vitro and in vivo comparison of a randomly coupled antibody fragment-enzyme conjugate with a site-specific conjugate.
    Werlen RC, Offord RE, Blakey DC, East SJ, Melton RG, Rose K.
    Biomed Pept Proteins Nucleic Acids; 1995; 1(5):251-4. PubMed ID: 9575348
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  • 3. Biodistribution of an antibody-enzyme conjugate for antibody-directed enzyme prodrug therapy in nude mice bearing a human colon adenocarcinoma xenograft.
    Stribbling SM, Martin J, Pedley RB, Boden JA, Sharma SK, Springer CJ.
    Cancer Chemother Pharmacol; 1997; 40(4):277-84. PubMed ID: 9225945
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  • 6. Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy.
    Kogelberg H, Tolner B, Sharma SK, Lowdell MW, Qureshi U, Robson M, Hillyer T, Pedley RB, Vervecken W, Contreras R, Begent RH, Chester KA.
    Glycobiology; 2007 Jan; 17(1):36-45. PubMed ID: 17000699
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  • 9. Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843.
    Wolfe LA, Mullin RJ, Laethem R, Blumenkopf TA, Cory M, Miller JF, Keith BR, Humphreys J, Smith GK.
    Bioconjug Chem; 1999 Jan; 10(1):38-48. PubMed ID: 9893962
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  • 12. ZD2767, an improved system for antibody-directed enzyme prodrug therapy that results in tumor regressions in colorectal tumor xenografts.
    Blakey DC, Burke PJ, Davies DH, Dowell RI, East SJ, Eckersley KP, Fitton JE, McDaid J, Melton RG, Niculescu-Duvaz IA, Pinder PE, Sharma SK, Wright AF, Springer CJ.
    Cancer Res; 1996 Jul 15; 56(14):3287-92. PubMed ID: 8764123
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  • 15. A calicheamicin conjugate with a fully humanized anti-MUC1 antibody shows potent antitumor effects in breast and ovarian tumor xenografts.
    Hamann PR, Hinman LM, Beyer CF, Lindh D, Upeslacis J, Shochat D, Mountain A.
    Bioconjug Chem; 2005 Jul 15; 16(2):354-60. PubMed ID: 15769089
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  • 18. Predictive physiologically based pharmacokinetic model for antibody-directed enzyme prodrug therapy.
    Fang L, Sun D.
    Drug Metab Dispos; 2008 Jun 15; 36(6):1153-65. PubMed ID: 18356268
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  • 19. Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate.
    Hamblett KJ, Senter PD, Chace DF, Sun MM, Lenox J, Cerveny CG, Kissler KM, Bernhardt SX, Kopcha AK, Zabinski RF, Meyer DL, Francisco JA.
    Clin Cancer Res; 2004 Oct 15; 10(20):7063-70. PubMed ID: 15501986
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  • 20. Galactosylated antibodies and antibody-enzyme conjugates in antibody-directed enzyme prodrug therapy.
    Sharma SK, Bagshawe KD, Burke PJ, Boden JA, Rogers GT, Springer CJ, Melton RG, Sherwood RF.
    Cancer; 1994 Feb 01; 73(3 Suppl):1114-20. PubMed ID: 8306255
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