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Journal Abstract Search

242 related items for PubMed ID: 9576953

  • 1. Genetic induction of immune tolerance to human clotting factor VIII in a mouse model for hemophilia A.
    Evans GL, Morgan RA.
    Proc Natl Acad Sci U S A; 1998 May 12; 95(10):5734-9. PubMed ID: 9576953
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  • 2. Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice.
    Peng B, Ye P, Blazar BR, Freeman GJ, Rawlings DJ, Ochs HD, Miao CH.
    Blood; 2008 Sep 01; 112(5):1662-72. PubMed ID: 18574023
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  • 3. Immunomodulation of transgene responses following naked DNA transfer of human factor VIII into hemophilia A mice.
    Miao CH, Ye P, Thompson AR, Rawlings DJ, Ochs HD.
    Blood; 2006 Jul 01; 108(1):19-27. PubMed ID: 16507778
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  • 5. Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy.
    Sack BK, Merchant S, Markusic DM, Nathwani AC, Davidoff AM, Byrne BJ, Herzog RW.
    PLoS One; 2012 Jul 01; 7(5):e37671. PubMed ID: 22655063
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  • 9. Hematopoietic stem cells encoding porcine factor VIII induce pro-coagulant activity in hemophilia A mice with pre-existing factor VIII immunity.
    Doering CB, Gangadharan B, Dukart HZ, Spencer HT.
    Mol Ther; 2007 Jun 01; 15(6):1093-9. PubMed ID: 17387335
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  • 10. B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin.
    Biswas M, Palaschak B, Kumar SRP, Rana J, Markusic DM.
    Front Immunol; 2020 Jun 01; 11():1293. PubMed ID: 32670285
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  • 11. Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant.
    McIntosh J, Lenting PJ, Rosales C, Lee D, Rabbanian S, Raj D, Patel N, Tuddenham EG, Christophe OD, McVey JH, Waddington S, Nienhuis AW, Gray JT, Fagone P, Mingozzi F, Zhou SZ, High KA, Cancio M, Ng CY, Zhou J, Morton CL, Davidoff AM, Nathwani AC.
    Blood; 2013 Apr 25; 121(17):3335-44. PubMed ID: 23426947
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  • 12. Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector.
    Balagué C, Zhou J, Dai Y, Alemany R, Josephs SF, Andreason G, Hariharan M, Sethi E, Prokopenko E, Jan HY, Lou YC, Hubert-Leslie D, Ruiz L, Zhang WW.
    Blood; 2000 Feb 01; 95(3):820-8. PubMed ID: 10648392
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  • 13. Adenovirus-mediated factor VIII gene expression results in attenuated anti-factor VIII-specific immunity in hemophilia A mice compared with factor VIII protein infusion.
    Bristol JA, Gallo-Penn A, Andrews J, Idamakanti N, Kaleko M, Connelly S.
    Hum Gene Ther; 2001 Sep 01; 12(13):1651-61. PubMed ID: 11535168
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  • 14. Long-term expression of human coagulation factor VIII in a tolerant mouse model using the φC31 integrase system.
    Chavez CL, Keravala A, Chu JN, Farruggio AP, Cuéllar VE, Voorberg J, Calos MP.
    Hum Gene Ther; 2012 Apr 01; 23(4):390-8. PubMed ID: 22077817
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  • 15. Induction of tolerance to human factor VIII in mice.
    Chao H, Walsh CE.
    Blood; 2001 May 15; 97(10):3311-2. PubMed ID: 11342466
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  • 16. Anti-CD3 antibodies modulate anti-factor VIII immune responses in hemophilia A mice after factor VIII plasmid-mediated gene therapy.
    Peng B, Ye P, Rawlings DJ, Ochs HD, Miao CH.
    Blood; 2009 Nov 12; 114(20):4373-82. PubMed ID: 19770362
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  • 18. A Treg-Selective IL-2 Mutein Prevents the Formation of Factor VIII Inhibitors in Hemophilia Mice Treated With Factor VIII Gene Therapy.
    Chen AC, Cai X, Li C, Khoryati L, Gavin MA, Miao CH.
    Front Immunol; 2020 Nov 12; 11():638. PubMed ID: 32411127
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  • 19. Expanding the ortholog approach for hemophilia treatment complicated by factor VIII inhibitors.
    Zakas PM, Vanijcharoenkarn K, Markovitz RC, Meeks SL, Doering CB.
    J Thromb Haemost; 2015 Jan 12; 13(1):72-81. PubMed ID: 25315236
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