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Journal Abstract Search


1474 related items for PubMed ID: 9578596

  • 1. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
    [Abstract] [Full Text] [Related]

  • 2. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
    Wester MR, Lasker JM, Johnson EF, Raucy JL.
    Drug Metab Dispos; 2000 Mar 01; 28(3):354-9. PubMed ID: 10681382
    [Abstract] [Full Text] [Related]

  • 3. Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes.
    Karam WG, Goldstein JA, Lasker JM, Ghanayem BI.
    Drug Metab Dispos; 1996 Oct 01; 24(10):1081-7. PubMed ID: 8894508
    [Abstract] [Full Text] [Related]

  • 4. Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations.
    Inoue K, Yamazaki H, Imiya K, Akasaka S, Guengerich FP, Shimada T.
    Pharmacogenetics; 1997 Apr 01; 7(2):103-13. PubMed ID: 9170147
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2002 May 01; 30(5):602-7. PubMed ID: 11950794
    [Abstract] [Full Text] [Related]

  • 6. Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
    Nakajima M, Inoue T, Shimada N, Tokudome S, Yamamoto T, Kuroiwa Y.
    Drug Metab Dispos; 1998 Mar 01; 26(3):261-6. PubMed ID: 9492390
    [Abstract] [Full Text] [Related]

  • 7. Cynomolgus monkey cytochrome P450 2C43: cDNA cloning, heterologous expression, purification and characterization.
    Mitsuda M, Iwasaki M, Asahi S.
    J Biochem; 2006 May 01; 139(5):865-72. PubMed ID: 16751594
    [Abstract] [Full Text] [Related]

  • 8. Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach.
    Venkatakrishnan K, von Moltke LL, Greenblatt DJ.
    J Pharm Sci; 1998 Jul 01; 87(7):845-53. PubMed ID: 9649353
    [Abstract] [Full Text] [Related]

  • 9. The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel.
    Gentile DM, Verhoeven CH, Shimada T, Back DJ.
    J Pharmacol Exp Ther; 1998 Dec 01; 287(3):975-82. PubMed ID: 9864282
    [Abstract] [Full Text] [Related]

  • 10. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H, Shimada T.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):161-9. PubMed ID: 9328296
    [Abstract] [Full Text] [Related]

  • 11. Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes.
    Srivastava PK, Yun CH, Beaune PH, Ged C, Guengerich FP.
    Mol Pharmacol; 1991 Jul 01; 40(1):69-79. PubMed ID: 1857342
    [Abstract] [Full Text] [Related]

  • 12. Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
    Giancarlo GM, Venkatakrishnan K, Granda BW, von Moltke LL, Greenblatt DJ.
    Eur J Clin Pharmacol; 2001 Apr 01; 57(1):31-6. PubMed ID: 11372587
    [Abstract] [Full Text] [Related]

  • 13. Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
    Yamazaki H, Inoue K, Shaw PM, Checovich WJ, Guengerich FP, Shimada T.
    J Pharmacol Exp Ther; 1997 Nov 01; 283(2):434-42. PubMed ID: 9353355
    [Abstract] [Full Text] [Related]

  • 14. Oxidative metabolism of omeprazole in human liver microsomes: cosegregation with S-mephenytoin 4'-hydroxylation.
    Chiba K, Kobayashi K, Manabe K, Tani M, Kamataki T, Ishizaki T.
    J Pharmacol Exp Ther; 1993 Jul 01; 266(1):52-9. PubMed ID: 8331574
    [Abstract] [Full Text] [Related]

  • 15. Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans.
    Goldstein JA, Faletto MB, Romkes-Sparks M, Sullivan T, Kitareewan S, Raucy JL, Lasker JM, Ghanayem BI.
    Biochemistry; 1994 Feb 22; 33(7):1743-52. PubMed ID: 8110777
    [Abstract] [Full Text] [Related]

  • 16. Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.
    Hamman MA, Thompson GA, Hall SD.
    Biochem Pharmacol; 1997 Jul 01; 54(1):33-41. PubMed ID: 9296349
    [Abstract] [Full Text] [Related]

  • 17. Human CYP2C-mediated stereoselective phenytoin hydroxylation in Japanese: difference in chiral preference of CYP2C9 and CYP2C19.
    Yasumori T, Chen LS, Li QH, Ueda M, Tsuzuki T, Goldstein JA, Kato R, Yamazoe Y.
    Biochem Pharmacol; 1999 Jun 01; 57(11):1297-303. PubMed ID: 10230773
    [Abstract] [Full Text] [Related]

  • 18. Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.
    Feierman DE, Lasker JM.
    Drug Metab Dispos; 1996 Sep 01; 24(9):932-9. PubMed ID: 8886601
    [Abstract] [Full Text] [Related]

  • 19. Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.
    Voorman RL, Payne NA, Wienkers LC, Hauer MJ, Sanders PE.
    Drug Metab Dispos; 2001 Jan 01; 29(1):41-7. PubMed ID: 11124228
    [Abstract] [Full Text] [Related]

  • 20. Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9.
    Tsao CC, Wester MR, Ghanayem B, Coulter SJ, Chanas B, Johnson EF, Goldstein JA.
    Biochemistry; 2001 Feb 20; 40(7):1937-44. PubMed ID: 11329260
    [Abstract] [Full Text] [Related]


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