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141 related items for PubMed ID: 9584221

  • 1. The selectivity filter of the N-methyl-D-aspartate receptor: a tryptophan residue controls block and permeation of Mg2+.
    Williams K, Pahk AJ, Kashiwagi K, Masuko T, Nguyen ND, Igarashi K.
    Mol Pharmacol; 1998 May; 53(5):933-41. PubMed ID: 9584221
    [Abstract] [Full Text] [Related]

  • 2. An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons.
    Kashiwagi K, Fukuchi J, Chao J, Igarashi K, Williams K.
    Mol Pharmacol; 1996 Jun; 49(6):1131-41. PubMed ID: 8649353
    [Abstract] [Full Text] [Related]

  • 3. Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits.
    Kashiwagi K, Pahk AJ, Masuko T, Igarashi K, Williams K.
    Mol Pharmacol; 1997 Oct; 52(4):701-13. PubMed ID: 9380034
    [Abstract] [Full Text] [Related]

  • 4. Activation of N-methyl-D-aspartate receptors by glycine: role of an aspartate residue in the M3-M4 loop of the NR1 subunit.
    Williams K, Chao J, Kashiwagi K, Masuko T, Igarashi K.
    Mol Pharmacol; 1996 Oct; 50(4):701-8. PubMed ID: 8863813
    [Abstract] [Full Text] [Related]

  • 5. Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.
    Wollmuth LP, Kuner T, Sakmann B.
    J Physiol; 1998 Jan 01; 506 ( Pt 1)(Pt 1):13-32. PubMed ID: 9481670
    [Abstract] [Full Text] [Related]

  • 6. The pore region of N-methyl-D-aspartate receptors differentially influences stimulation and block by spermine.
    Jin L, Miyazaki M, Mizuno S, Takigawa M, Hirose T, Nishimura K, Toida T, Williams K, Kashiwagi K, Igarashi K.
    J Pharmacol Exp Ther; 2008 Oct 01; 327(1):68-77. PubMed ID: 18632991
    [Abstract] [Full Text] [Related]

  • 7. Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channel.
    Mori H, Masaki H, Yamakura T, Mishina M.
    Nature; 1992 Aug 20; 358(6388):673-5. PubMed ID: 1386653
    [Abstract] [Full Text] [Related]

  • 8. An acidic amino acid in the N-methyl-D-aspartate receptor that is important for spermine stimulation.
    Williams K, Kashiwagi K, Fukuchi J, Igarashi K.
    Mol Pharmacol; 1995 Dec 20; 48(6):1087-98. PubMed ID: 8848009
    [Abstract] [Full Text] [Related]

  • 9. Probing the Mg2+ blockade site of an N-methyl-D-aspartate (NMDA) receptor with unnatural amino acid mutagenesis.
    McMenimen KA, Dougherty DA, Lester HA, Petersson EJ.
    ACS Chem Biol; 2006 May 23; 1(4):227-34. PubMed ID: 17163677
    [Abstract] [Full Text] [Related]

  • 10. Intracellular Mg2+ interacts with structural determinants of the narrow constriction contributed by the NR1-subunit in the NMDA receptor channel.
    Wollmuth LP, Kuner T, Sakmann B.
    J Physiol; 1998 Jan 01; 506 ( Pt 1)(Pt 1):33-52. PubMed ID: 9481671
    [Abstract] [Full Text] [Related]

  • 11. Cyclophane and acyclic cyclophane: novel channel blockers of N-methyl-D-aspartate receptor.
    Masuko T, Nagaoka H, Miyake M, Metori K, Kizawa Y, Kashiwagi K, Igarashi K, Kusama T.
    Neurochem Int; 2007 Jan 01; 50(2):443-9. PubMed ID: 17113196
    [Abstract] [Full Text] [Related]

  • 12. Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B N-methyl-D-aspartate receptors: Implications for studies of synaptic transmission.
    Frizelle PA, Chen PE, Wyllie DJ.
    Mol Pharmacol; 2006 Sep 01; 70(3):1022-32. PubMed ID: 16778008
    [Abstract] [Full Text] [Related]

  • 13. Pharmacological implications of two distinct mechanisms of interaction of memantine with N-methyl-D-aspartate-gated channels.
    Chen HS, Lipton SA.
    J Pharmacol Exp Ther; 2005 Sep 01; 314(3):961-71. PubMed ID: 15901795
    [Abstract] [Full Text] [Related]

  • 14. Site within N-Methyl-D-aspartate receptor pore modulates channel gating.
    Chen N, Li B, Murphy TH, Raymond LA.
    Mol Pharmacol; 2004 Jan 01; 65(1):157-64. PubMed ID: 14722247
    [Abstract] [Full Text] [Related]

  • 15. Anthraquinone polyamines: novel channel blockers of N-methyl-D-aspartate receptors.
    Kashiwagi K, Williams K, Igarashi K.
    Amino Acids; 2007 Aug 01; 33(2):299-304. PubMed ID: 17404801
    [Abstract] [Full Text] [Related]

  • 16. Comparative studies of anthraquinone- and anthracene-tetraamines as blockers of N-methyl-D-aspartate receptors.
    Jin L, Sugiyama H, Takigawa M, Katagiri D, Tomitori H, Nishimura K, Kaur N, Phanstiel O, Kitajima M, Takayama H, Okawara T, Williams K, Kashiwagi K, Igarashi K.
    J Pharmacol Exp Ther; 2007 Jan 01; 320(1):47-55. PubMed ID: 17050777
    [Abstract] [Full Text] [Related]

  • 17. Multiple structural elements determine subunit specificity of Mg2+ block in NMDA receptor channels.
    Kuner T, Schoepfer R.
    J Neurosci; 1996 Jun 01; 16(11):3549-58. PubMed ID: 8642401
    [Abstract] [Full Text] [Related]

  • 18. Mutations within the selectivity filter of the NMDA receptor-channel influence voltage dependent block by 5-hydroxytryptamine.
    Kloda A, Adams DJ.
    Br J Pharmacol; 2006 Sep 01; 149(2):163-9. PubMed ID: 16894346
    [Abstract] [Full Text] [Related]

  • 19. Differential effects of linear and cyclic polyamines on NMDA receptor activities.
    Masuko T, Miyake M, Kusama-Eguchi K, Koike T, Kimura E, Kizawa Y, Kashiwagi K, Igarashi K, Kusama T.
    Neurochem Int; 2008 Jul 01; 53(1-2):38-44. PubMed ID: 18556092
    [Abstract] [Full Text] [Related]

  • 20. Anthraquinone polyamines: novel channel blockers to study N-methyl-D-aspartate receptors.
    Kashiwagi K, Tanaka I, Tamura M, Sugiyama H, Okawara T, Otsuka M, Sabado TN, Williams K, Igarashi K.
    J Pharmacol Exp Ther; 2004 Jun 01; 309(3):884-93. PubMed ID: 14764657
    [Abstract] [Full Text] [Related]

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