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Journal Abstract Search

137 related items for PubMed ID: 9585974

  • 1. Synthesis of DHPA analogs and their inhibitory activities of human recombinant S-adenosyl-L-homocysteine hydrolase.
    Kitade Y, Nakanishi M, Hosoya A, Hiraoka A, Hayashi M, Mori K, Gotoh T, Yatome C.
    Nucleic Acids Symp Ser; 1997; (37):11-2. PubMed ID: 9585974
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of S-adenosyl-L-homocysteine hydrolase inhibitors and their biological activities.
    Kitade Y, Kozaki A, Gotoh T, Miwa T, Nakanishi M, Yatome C.
    Nucleic Acids Symp Ser; 1999; (42):25-6. PubMed ID: 10780361
    [Abstract] [Full Text] [Related]

  • 3. [Synthesis of S-9-(2,3-dihydroxypropyl)adenine (DHPA) analogs and their inhibition of S-adenosyl-L-homocysteine (SAH) hydrolase].
    Wang GX, Wang L, Zhao ZZ, Zhang T, Tao PZ.
    Yao Xue Xue Bao; 1997; 32(3):188-92. PubMed ID: 11327019
    [Abstract] [Full Text] [Related]

  • 4. 9-[(2'S,3'S)-3'-formyl-2',3'-dihydroxypropyl]adenine: a facile affinity-labeling probe of human S-adenosyl-L-homocysteine hydrolase.
    Kitade Y, Nakanishi M, Yatome C.
    Bioorg Med Chem Lett; 1999 Sep 20; 9(18):2737-40. PubMed ID: 10509926
    [Abstract] [Full Text] [Related]

  • 5. [The establishment and application of antiviral screening model targeted on SAH hydrolase].
    Zhang T, Tao P, Wang L, Chen X, Wang G.
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi; 2002 Mar 20; 16(1):55-8. PubMed ID: 11986748
    [Abstract] [Full Text] [Related]

  • 6. Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine).
    Robins MJ, Wnuk SF, Yang X, Yuan CS, Borchardt RT, Balzarini J, De Clercq E.
    J Med Chem; 1998 Sep 24; 41(20):3857-64. PubMed ID: 9748360
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase.
    Kitade Y, Kojima H, Zulfiqur F, Yabe S, Yamagiwa D, Ito Y, Nakanishi M, Ueno Y, Kim HS, Wataya Y.
    Nucleic Acids Res Suppl; 2003 Sep 24; (3):5-6. PubMed ID: 14510352
    [Abstract] [Full Text] [Related]

  • 8. Synthesis of carbocyclic nucleosides and their SAH hydrolase inhibitory activities.
    Kitade Y, Kozaki A, Miwa T, Nakanishi M, Yatome C.
    Nucleic Acids Symp Ser; 2000 Sep 24; (44):111-2. PubMed ID: 12903293
    [Abstract] [Full Text] [Related]

  • 9. Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.
    Wnuk SF, Valdez CA, Khan J, Moutinho P, Robins MJ, Yang X, Borchardt RT, Balzarini J, De Clercq E.
    J Med Chem; 2000 Mar 23; 43(6):1180-6. PubMed ID: 10737751
    [Abstract] [Full Text] [Related]

  • 10. Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine.
    Wnuk SF, Mao Y, Yuan CS, Borchardt RT, Andrei G, Balzarini J, De Clercq E, Robins MJ.
    J Med Chem; 1998 Jul 30; 41(16):3078-83. PubMed ID: 9685247
    [Abstract] [Full Text] [Related]

  • 11. Aristeromycin-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase.
    Liu S, Yuan CS, Borchardt RT.
    J Med Chem; 1996 Jun 07; 39(12):2347-53. PubMed ID: 8691429
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase.
    Jeong LS, Yoo SJ, Lee KM, Koo MJ, Choi WJ, Kim HO, Moon HR, Lee MY, Park JG, Lee SK, Chun MW.
    J Med Chem; 2003 Jan 16; 46(2):201-3. PubMed ID: 12519056
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, mechanism of action, and antiviral activity of a new series of covalent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase.
    Guillerm G, Guillerm D, Vandenplas-Witkowki C, Rogniaux H, Carte N, Leize E, Van Dorsselaer A, De Clercq E, Lambert C.
    J Med Chem; 2001 Aug 16; 44(17):2743-52. PubMed ID: 11495586
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of purine-containing butenolides.
    Hakimelahi GH, Mei NW, Moosavi-Movahedi AA, Davari H, Hakimelahi S, King KY, Hwu JR, Wen YS.
    J Med Chem; 2001 May 24; 44(11):1749-57. PubMed ID: 11356110
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of halogenated 9-(dihydroxycyclopent-4'-enyl) adenines and their inhibitory activities against S-adenosylhomocysteine hydrolase.
    Jeong LS, Park JG, Choi WJ, Moon HR, Lee KM, Kim HO, Kim HD, Chun MW, Park HY, Kim K, Sheen YY.
    Nucleosides Nucleotides Nucleic Acids; 2003 May 24; 22(5-8):919-21. PubMed ID: 14565311
    [Abstract] [Full Text] [Related]

  • 16. Inactivation of S-adenosyl-L-homocysteine hydrolase with fluorinated analogs of 2'- and 3'-deoxy-5'-methylthioadenosine.
    Guillerm D, Guillerm G, Witkowski-Vandenplas C.
    Nucleosides Nucleotides Nucleic Acids; 2001 May 24; 20(4-7):689-93. PubMed ID: 11563093
    [Abstract] [Full Text] [Related]

  • 17. Sugar-modified conjugated diene analogues of adenosine and uridine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.
    Wnuk SF, Ro BO, Valdez CA, Lewandowska E, Valdez NX, Sacasa PR, Yin D, Zhang J, Borchardt RT, De Clercq E.
    J Med Chem; 2002 Jun 06; 45(12):2651-8. PubMed ID: 12036374
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of an alpha-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase.
    Steere JA, Sampson PB, Honek JF.
    Bioorg Med Chem Lett; 2002 Feb 11; 12(3):457-60. PubMed ID: 11814819
    [Abstract] [Full Text] [Related]

  • 19. The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi.
    Cai S, Li QS, Borchardt RT, Kuczera K, Schowen RL.
    Bioorg Med Chem; 2007 Dec 01; 15(23):7281-7. PubMed ID: 17845853
    [Abstract] [Full Text] [Related]

  • 20. Homocysteine potentiates the antiviral and cytostatic activity of those nucleoside analogues that are targeted at S-adenosylhomocysteine hydrolase.
    De Clercq E, Cools M, Balzarini J.
    Biochem Pharmacol; 1989 Jun 01; 38(11):1771-8. PubMed ID: 2735935
    [Abstract] [Full Text] [Related]

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