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173 related items for PubMed ID: 9596679

  • 1. Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells.
    Giannì M, Koken MH, Chelbi-Alix MK, Benoit G, Lanotte M, Chen Z, de Thé H.
    Blood; 1998 Jun 01; 91(11):4300-10. PubMed ID: 9596679
    [Abstract] [Full Text] [Related]

  • 2. Arsenic trioxide (As2O3)-induced apoptosis and differentiation in retinoic acid-resistant acute promyelocytic leukemia model in hGM-CSF-producing transgenic SCID mice.
    Kinjo K, Kizaki M, Muto A, Fukuchi Y, Umezawa A, Yamato K, Nishihara T, Hata J, Ito M, Ueyama Y, Ikeda Y.
    Leukemia; 2000 Mar 01; 14(3):431-8. PubMed ID: 10720138
    [Abstract] [Full Text] [Related]

  • 3. Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner.
    Wang ZG, Rivi R, Delva L, König A, Scheinberg DA, Gambacorti-Passerini C, Gabrilove JL, Warrell RP, Pandolfi PP.
    Blood; 1998 Sep 01; 92(5):1497-504. PubMed ID: 9716575
    [Abstract] [Full Text] [Related]

  • 4. Arsenic enhances the activation of Stat1 by interferon gamma leading to synergistic expression of IRF-1.
    Chelbi-alix MK, Bobé P, Benoit G, Canova A, Pine R.
    Oncogene; 2003 Dec 11; 22(57):9121-30. PubMed ID: 14668793
    [Abstract] [Full Text] [Related]

  • 5. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia.
    Cai X, Shen YL, Zhu Q, Jia PM, Yu Y, Zhou L, Huang Y, Zhang JW, Xiong SM, Chen SJ, Wang ZY, Chen Z, Chen GQ.
    Leukemia; 2000 Feb 11; 14(2):262-70. PubMed ID: 10673743
    [Abstract] [Full Text] [Related]

  • 6. Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells.
    Yan H, Peng ZG, Wu YL, Jiang Y, Yu Y, Huang Y, Zhu YS, Zhao Q, Chen GQ.
    Haematologica; 2005 Dec 11; 90(12):1607-16. PubMed ID: 16330433
    [Abstract] [Full Text] [Related]

  • 7. Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells.
    Shao W, Fanelli M, Ferrara FF, Riccioni R, Rosenauer A, Davison K, Lamph WW, Waxman S, Pelicci PG, Lo Coco F, Avvisati G, Testa U, Peschle C, Gambacorti-Passerini C, Nervi C, Miller WH.
    J Natl Cancer Inst; 1998 Jan 21; 90(2):124-33. PubMed ID: 9450572
    [Abstract] [Full Text] [Related]

  • 8. In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies.
    Giannì M, de Thé H.
    Leukemia; 1999 May 21; 13(5):739-49. PubMed ID: 10374879
    [Abstract] [Full Text] [Related]

  • 9. PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.
    Sternsdorf T, Puccetti E, Jensen K, Hoelzer D, Will H, Ottmann OG, Ruthardt M.
    Mol Cell Biol; 1999 Jul 21; 19(7):5170-8. PubMed ID: 10373566
    [Abstract] [Full Text] [Related]

  • 10. Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient.
    Koken MH, Daniel MT, Gianni M, Zelent A, Licht J, Buzyn A, Minard P, Degos L, Varet B, de Thé H.
    Oncogene; 1999 Jan 28; 18(4):1113-8. PubMed ID: 10023688
    [Abstract] [Full Text] [Related]

  • 11. Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis.
    Kitamura K, Minami Y, Yamamoto K, Akao Y, Kiyoi H, Saito H, Naoe T.
    Leukemia; 2000 Oct 28; 14(10):1743-50. PubMed ID: 11021749
    [Abstract] [Full Text] [Related]

  • 12. A novel differentiation-inducing therapy for acute promyelocytic leukemia with a combination of arsenic trioxide and GM-CSF.
    Muto A, Kizaki M, Kawamura C, Matsushita H, Fukuchi Y, Umezawa A, Yamada T, Hata J, Hozumi N, Yamato K, Ito M, Ueyama Y, Ikeda Y.
    Leukemia; 2001 Aug 28; 15(8):1176-84. PubMed ID: 11480559
    [Abstract] [Full Text] [Related]

  • 13. Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation.
    Wang QQ, Zhou XY, Zhang YF, Bu N, Zhou J, Cao FL, Naranmandura H.
    Oncotarget; 2015 Sep 22; 6(28):25646-59. PubMed ID: 26213848
    [Abstract] [Full Text] [Related]

  • 14. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins.
    Chen GQ, Zhu J, Shi XG, Ni JH, Zhong HJ, Si GY, Jin XL, Tang W, Li XS, Xong SM, Shen ZX, Sun GL, Ma J, Zhang P, Zhang TD, Gazin C, Naoe T, Chen SJ, Wang ZY, Chen Z.
    Blood; 1996 Aug 01; 88(3):1052-61. PubMed ID: 8704214
    [Abstract] [Full Text] [Related]

  • 15. Targeted removal of PML-RARalpha protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia.
    Jing Y, Xia L, Waxman S.
    Blood; 2002 Aug 01; 100(3):1008-13. PubMed ID: 12130515
    [Abstract] [Full Text] [Related]

  • 16. Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo.
    Jing Y, Wang L, Xia L, Chen GQ, Chen Z, Miller WH, Waxman S.
    Blood; 2001 Jan 01; 97(1):264-9. PubMed ID: 11133770
    [Abstract] [Full Text] [Related]

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  • 19. [In vitro study of the effects of arsenic trioxide combined with 8-CPT-cAMP on differentiation induction in retinoic acid resistant acute promyelocytic leukemia cells].
    Zhu Q, Yu Y, Jia PM, Cai X, Chen SJ, Chen Z, Wang ZY, Tong JH.
    Zhonghua Xue Ye Xue Za Zhi; 2003 Jan 01; 24(1):6-9. PubMed ID: 12679001
    [Abstract] [Full Text] [Related]

  • 20. [In vitro study on arsenic trioxide-induced apoptosis of retinoic acid resistant acute promyelocytic leukemia cell line(MR-2)].
    Cai X, Jia P, Shi X.
    Zhonghua Xue Ye Xue Za Zhi; 1998 Jul 01; 19(7):339-41. PubMed ID: 11189513
    [Abstract] [Full Text] [Related]

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