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Journal Abstract Search

130 related items for PubMed ID: 9600353

  • 1. Characterization of xenobiotic-metabolizing enzymes and nitrosamine metabolism in the human esophagus.
    Smith TJ, Liao A, Wang LD, Yang GY, Starcic S, Philbert MA, Yang CS.
    Carcinogenesis; 1998 Apr; 19(4):667-72. PubMed ID: 9600353
    [Abstract] [Full Text] [Related]

  • 2. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H, Inui Y, Yun CH, Guengerich FP, Shimada T.
    Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
    [Abstract] [Full Text] [Related]

  • 3. Evidence for metabolic activation of N'-nitrosonornicotine and N-nitrosobenzylmethylamine by a rat nasal coumarin hydroxylase.
    Patten CJ, Peterson LA, Murphy SE.
    Drug Metab Dispos; 1998 Feb; 26(2):177-80. PubMed ID: 9456305
    [Abstract] [Full Text] [Related]

  • 4. Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats.
    Guo Z, Smith TJ, Wang E, Sadrieh N, Ma Q, Thomas PE, Yang CS.
    Carcinogenesis; 1992 Dec; 13(12):2205-10. PubMed ID: 1473225
    [Abstract] [Full Text] [Related]

  • 5. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ, Smith TJ, Murphy SE, Wang MH, Lee J, Tynes RE, Koch P, Yang CS.
    Arch Biochem Biophys; 1996 Sep 01; 333(1):127-38. PubMed ID: 8806763
    [Abstract] [Full Text] [Related]

  • 6. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ, Smith TJ, Friesen MJ, Tynes RE, Yang CS, Murphy SE.
    Carcinogenesis; 1997 Aug 01; 18(8):1623-30. PubMed ID: 9276639
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  • 8. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Smith TJ, Stoner GD, Yang CS.
    Cancer Res; 1995 Dec 01; 55(23):5566-73. PubMed ID: 7585636
    [Abstract] [Full Text] [Related]

  • 9. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
    Smith TJ, Guo Z, Guengerich FP, Yang CS.
    Carcinogenesis; 1996 Apr 01; 17(4):809-13. PubMed ID: 8625495
    [Abstract] [Full Text] [Related]

  • 10. Comparative metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured F344 rat oral tissue and esophagus.
    Murphy SE, Heiblum R, Trushin N.
    Cancer Res; 1990 Aug 01; 50(15):4685-91. PubMed ID: 2369743
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of carcinogenic nitrosamines by rat nasal mucosa and the effect of diallyl sulfide.
    Hong JY, Smith T, Lee MJ, Li WS, Ma BL, Ning SM, Brady JF, Thomas PE, Yang CS.
    Cancer Res; 1991 Mar 01; 51(5):1509-14. PubMed ID: 1997191
    [Abstract] [Full Text] [Related]

  • 12. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ, Liao AM, Liu Y, Jones AB, Anderson LM, Yang CS.
    Carcinogenesis; 1997 Aug 01; 18(8):1577-84. PubMed ID: 9276633
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  • 15. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
    Staretz ME, Murphy SE, Patten CJ, Nunes MG, Koehl W, Amin S, Koenig LA, Guengerich FP, Hecht SS.
    Drug Metab Dispos; 1997 Feb 01; 25(2):154-62. PubMed ID: 9029045
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of Nitrosamide Formation in the Cytochrome P450-Mediated Metabolism of Tobacco-Specific Nitrosamines.
    Carlson ES, Upadhyaya P, Hecht SS.
    Chem Res Toxicol; 2016 Dec 19; 29(12):2194-2205. PubMed ID: 27989137
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ, Guo Z, Gonzalez FJ, Guengerich FP, Stoner GD, Yang CS.
    Cancer Res; 1992 Apr 01; 52(7):1757-63. PubMed ID: 1312898
    [Abstract] [Full Text] [Related]

  • 18. A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6.
    Crespi CL, Penman BW, Gelboin HV, Gonzalez FJ.
    Carcinogenesis; 1991 Jul 01; 12(7):1197-201. PubMed ID: 2070484
    [Abstract] [Full Text] [Related]

  • 19. Cytochrome P450 2A-catalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, N-nitrosopiperidine, and N-nitrosopyrrolidine.
    Wong HL, Murphy SE, Hecht SS.
    Chem Res Toxicol; 2005 Jan 01; 18(1):61-9. PubMed ID: 15651850
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
    Smith TJ, Guo ZY, Thomas PE, Chung FL, Morse MA, Elkind K, Yang CS.
    Cancer Res; 1990 Nov 01; 50(21):6817-22. PubMed ID: 2208146
    [Abstract] [Full Text] [Related]

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