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Journal Abstract Search

134 related items for PubMed ID: 9605751

  • 21. Tirapazamine cytotoxicity for neuroblastoma is p53 dependent.
    Yang B, Reynolds CP.
    Clin Cancer Res; 2005 Apr 01; 11(7):2774-80. PubMed ID: 15814660
    [Abstract] [Full Text] [Related]

  • 22. Multicellular resistance to tirapazamine is due to restricted extravascular transport: a pharmacokinetic/pharmacodynamic study in HT29 multicellular layer cultures.
    Hicks KO, Pruijn FB, Sturman JR, Denny WA, Wilson WR.
    Cancer Res; 2003 Sep 15; 63(18):5970-7. PubMed ID: 14522924
    [Abstract] [Full Text] [Related]

  • 23. Antagonism of buthionine sulfoximine cytotoxicity for human neuroblastoma cell lines by hypoxia is reversed by the bioreductive agent tirapazamine.
    Yang B, Keshelava N, Anderson CP, Reynolds CP.
    Cancer Res; 2003 Apr 01; 63(7):1520-6. PubMed ID: 12670899
    [Abstract] [Full Text] [Related]

  • 24. Potentially lethal damage repair by total and quiescent tumor cells following various DNA-damaging treatments.
    Masunaga S, Ono K, Hori H, Suzuki M, Kinashi Y, Takagaki M, Kasai S, Nagasawa H, Uto Y.
    Radiat Med; 1999 Apr 01; 17(4):259-64. PubMed ID: 10510897
    [Abstract] [Full Text] [Related]

  • 25. Non-nuclear localized human NOSII enhances the bioactivation and toxicity of tirapazamine (SR4233) in vitro.
    Chinje EC, Cowen RL, Feng J, Sharma SP, Wind NS, Harris AL, Stratford IJ.
    Mol Pharmacol; 2003 Jun 01; 63(6):1248-55. PubMed ID: 12761334
    [Abstract] [Full Text] [Related]

  • 26. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 01; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 27. Enhanced conversion of DNA radical damage to double strand breaks by 1,2,4-benzotriazine 1,4-dioxides linked to a DNA binder compared to tirapazamine.
    Anderson RF, Harris TA, Hay MP, Denny WA.
    Chem Res Toxicol; 2003 Nov 01; 16(11):1477-83. PubMed ID: 14615975
    [Abstract] [Full Text] [Related]

  • 28. Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin.
    Kovacs MS, Hocking DJ, Evans JW, Siim BG, Wouters BG, Brown JM.
    Br J Cancer; 1999 Jun 01; 80(8):1245-51. PubMed ID: 10376978
    [Abstract] [Full Text] [Related]

  • 29. Dual action of tirapazamine in the induction of DNA strand breaks.
    Jones GD, Weinfeld M.
    Cancer Res; 1996 Apr 01; 56(7):1584-90. PubMed ID: 8603406
    [Abstract] [Full Text] [Related]

  • 30. Tirapazamine: a new drug producing tumor specific enhancement of platinum-based chemotherapy in non-small-cell lung cancer.
    Wouters BG, Wang LH, Brown JM.
    Ann Oncol; 1999 Apr 01; 10 Suppl 5():S29-33. PubMed ID: 10582136
    [Abstract] [Full Text] [Related]

  • 31. NADPH:cytochrome c (P450) reductase activates tirapazamine (SR4233) to restore hypoxic and oxic cytotoxicity in an aerobic resistant derivative of the A549 lung cancer cell line.
    Saunders MP, Patterson AV, Chinje EC, Harris AL, Stratford IJ.
    Br J Cancer; 2000 Feb 01; 82(3):651-6. PubMed ID: 10682679
    [Abstract] [Full Text] [Related]

  • 32. Cytotoxicity of Tirapazamine (3-Amino-1,2,4-benzotriazine-1,4-dioxide)-Induced DNA Damage in Chicken DT40 Cells.
    Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga SI, Tano K.
    Chem Res Toxicol; 2017 Feb 20; 30(2):699-704. PubMed ID: 27943678
    [Abstract] [Full Text] [Related]

  • 33. Antitumor agents 4. Characterization of free radicals produced during reduction of the antitumor drug 5H-pyridophenoxazin-5-one: an EPR study.
    Alberti A, Bolognese A, Guerra M, Lavecchia A, Macciantelli D, Marcaccio M, Novellino E, Paolucci F.
    Biochemistry; 2003 Oct 21; 42(41):11924-31. PubMed ID: 14556623
    [Abstract] [Full Text] [Related]

  • 34. Characterization of radicals formed following enzymatic reduction of 3-substituted analogues of the hypoxia-selective cytotoxin 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).
    Shinde SS, Maroz A, Hay MP, Patterson AV, Denny WA, Anderson RF.
    J Am Chem Soc; 2010 Mar 03; 132(8):2591-9. PubMed ID: 20141134
    [Abstract] [Full Text] [Related]

  • 35. On the mechanism of reaction of radicals with tirapazamine.
    Shi X, Mandel SM, Platz MS.
    J Am Chem Soc; 2007 Apr 18; 129(15):4542-50. PubMed ID: 17381087
    [Abstract] [Full Text] [Related]

  • 36. Metabolism of SR 4233 by Chinese hamster ovary cells: basis of selective hypoxic cytotoxicity.
    Baker MA, Zeman EM, Hirst VK, Brown JM.
    Cancer Res; 1988 Nov 01; 48(21):5947-52. PubMed ID: 3167847
    [Abstract] [Full Text] [Related]

  • 37. Tirapazamine-induced DNA damage measured using the comet assay correlates with cytotoxicity towards hypoxic tumour cells in vitro.
    Siim BG, van Zijl PL, Brown JM.
    Br J Cancer; 1996 Apr 01; 73(8):952-60. PubMed ID: 8611431
    [Abstract] [Full Text] [Related]

  • 38. Direct evidence for bimodal DNA damage induced by tirapazamine.
    Daniels JS, Gates KS, Tronche C, Greenberg MM.
    Chem Res Toxicol; 1998 Nov 01; 11(11):1254-7. PubMed ID: 9815184
    [Abstract] [Full Text] [Related]

  • 39. Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity.
    Guise CP, Abbattista MR, Anderson RF, Li D, Taghipouran R, Tsai A, Lee SJ, Smaill JB, Denny WA, Hay MP, Wilson WR, Hicks KO, Patterson AV.
    Molecules; 2020 Oct 22; 25(21):. PubMed ID: 33105798
    [Abstract] [Full Text] [Related]

  • 40. DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2).
    Chowdhury G, Junnotula V, Daniels JS, Greenberg MM, Gates KS.
    J Am Chem Soc; 2007 Oct 24; 129(42):12870-7. PubMed ID: 17900117
    [Abstract] [Full Text] [Related]

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