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Journal Abstract Search

327 related items for PubMed ID: 9614217

  • 1. On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor.
    Christopoulos A, Pierce TL, Sorman JL, El-Fakahany EE.
    Mol Pharmacol; 1998 Jun; 53(6):1120-30. PubMed ID: 9614217
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor.
    Christopoulos A, Parsons AM, El-Fakahany EE.
    J Pharmacol Exp Ther; 1999 Jun; 289(3):1220-8. PubMed ID: 10336509
    [Abstract] [Full Text] [Related]

  • 3. Persistent binding and functional antagonism by xanomeline at the muscarinic M5 receptor.
    Grant MK, El-Fakahany EE.
    J Pharmacol Exp Ther; 2005 Oct; 315(1):313-9. PubMed ID: 16002459
    [Abstract] [Full Text] [Related]

  • 4. Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.
    Jakubík J, El-Fakahany EE, Dolezal V.
    Mol Pharmacol; 2006 Aug; 70(2):656-66. PubMed ID: 16675658
    [Abstract] [Full Text] [Related]

  • 5. Long-term changes in the muscarinic M1 receptor induced by instantaneous formation of wash-resistant xanomeline-receptor complex.
    De Lorme KC, Grant MK, Noetzel MJ, Polson SB, El-Fakahany EE.
    J Pharmacol Exp Ther; 2007 Dec; 323(3):868-76. PubMed ID: 17855477
    [Abstract] [Full Text] [Related]

  • 6. Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor.
    Jakubík J, Tucek S, El-Fakahany EE.
    J Pharmacol Exp Ther; 2002 Jun; 301(3):1033-41. PubMed ID: 12023535
    [Abstract] [Full Text] [Related]

  • 7. Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1 and 5-HT2 receptors.
    Watson J, Brough S, Coldwell MC, Gager T, Ho M, Hunter AJ, Jerman J, Middlemiss DN, Riley GJ, Brown AM.
    Br J Pharmacol; 1998 Dec; 125(7):1413-20. PubMed ID: 9884068
    [Abstract] [Full Text] [Related]

  • 8. Low-affinity M(2) receptor binding state mediates mouse atrial bradycardia: comparative effects of carbamylcholine and the M(1) receptor agonists sabcomeline and xanomeline.
    Stengel PW, Cohen ML.
    J Pharmacol Exp Ther; 2001 Mar; 296(3):818-24. PubMed ID: 11181912
    [Abstract] [Full Text] [Related]

  • 9. Role of receptor protein and membrane lipids in xanomeline wash-resistant binding to muscarinic M1 receptors.
    Jakubík J, Tucek S, El-Fakahany EE.
    J Pharmacol Exp Ther; 2004 Jan; 308(1):105-10. PubMed ID: 14569060
    [Abstract] [Full Text] [Related]

  • 10. Novel persistent activation of muscarinic M1 receptors by xanomeline.
    Christopoulos A, El-Fakahany EE.
    Eur J Pharmacol; 1997 Sep 03; 334(1):R3-4. PubMed ID: 9346340
    [Abstract] [Full Text] [Related]

  • 11. Effects of the M1 agonist xanomeline on processing of human beta-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells.
    DeLapp N, Wu S, Belagaje R, Johnstone E, Little S, Shannon H, Bymaster F, Calligaro D, Mitch C, Whitesitt C, Ward J, Sheardown M, Fink-Jensen A, Jeppesen L, Thomsen C, Sauerberg P.
    Biochem Biophys Res Commun; 1998 Mar 06; 244(1):156-60. PubMed ID: 9514902
    [Abstract] [Full Text] [Related]

  • 12. Wash-resistantly bound xanomeline inhibits acetylcholine release by persistent activation of presynaptic M(2) and M(4) muscarinic receptors in rat brain.
    Machová E, Jakubík J, El-Fakahany EE, Dolezal V.
    J Pharmacol Exp Ther; 2007 Jul 06; 322(1):316-23. PubMed ID: 17446301
    [Abstract] [Full Text] [Related]

  • 13. Long-term wash-resistant effects of brief interaction of xanomeline at the M1 muscarinic receptor.
    De Lorme KC, Sikorski KL, Grant MK, El-Fakahany EE.
    Neurosci Lett; 2006 Dec 13; 410(1):11-4. PubMed ID: 17052840
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  • 17. Flavin-containing monooxygenase-mediated N-oxidation of the M(1)-muscarinic agonist xanomeline.
    Ring BJ, Wrighton SA, Aldridge SL, Hansen K, Haehner B, Shipley LA.
    Drug Metab Dispos; 1999 Oct 13; 27(10):1099-103. PubMed ID: 10497134
    [Abstract] [Full Text] [Related]

  • 18. Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 receptor knockout mice.
    Woolley ML, Carter HJ, Gartlon JE, Watson JM, Dawson LA.
    Eur J Pharmacol; 2009 Jan 28; 603(1-3):147-9. PubMed ID: 19111716
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and evaluation of xanomeline analogs--probing the wash-resistant phenomenon at the M1 muscarinic acetylcholine receptor.
    Kane BE, Grant MK, El-Fakahany EE, Ferguson DM.
    Bioorg Med Chem; 2008 Feb 01; 16(3):1376-92. PubMed ID: 17977730
    [Abstract] [Full Text] [Related]

  • 20. Activation of transfected M1 or M3 muscarinic acetylcholine receptors induces cell-cell adhesion of Chinese hamster ovary cells expressing endogenous cadherins.
    Shafer SH, Puhl HL, Phelps SH, Williams CL.
    Exp Cell Res; 1999 Apr 10; 248(1):148-59. PubMed ID: 10094822
    [Abstract] [Full Text] [Related]

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