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Journal Abstract Search


349 related items for PubMed ID: 9620626

  • 1. Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Farde L, Ginovart N, Luthra SK, Gunn RN, Bench CJ, Sargent PA, Grasby PM.
    Nucl Med Biol; 1998 Apr; 25(3):215-23. PubMed ID: 9620626
    [Abstract] [Full Text] [Related]

  • 2. Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Ginovart N, Luthra SK, Bench CJ, Grasby PM, Wikström H, Barf T, Cliffe IA, Fletcher A, Farde L.
    Nucl Med Biol; 1996 Jul; 23(5):627-34. PubMed ID: 8905828
    [Abstract] [Full Text] [Related]

  • 3. [carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo.
    Pike VW, Halldin C, McCarron JA, Lundkvist C, Hirani E, Olsson H, Hume SP, Karlsson P, Osman S, Swahn CG, Hall H, Wikström H, Mensonidas M, Poole KG, Farde L.
    Eur J Nucl Med; 1998 Apr; 25(4):338-46. PubMed ID: 9553162
    [Abstract] [Full Text] [Related]

  • 4. New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.
    Sandell J, Halldin C, Pike VW, Chou YH, Varnäs K, Hall H, Marchais S, Nowicki B, Wikström HV, Swahn CG, Farde L.
    Nucl Med Biol; 2001 Feb; 28(2):177-85. PubMed ID: 11295428
    [Abstract] [Full Text] [Related]

  • 5. Two C-methyl derivatives of [11C]WAY-100635--effects of an amido alpha-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey.
    McCarron JA, Marchais-Oberwinkler S, Pike VW, Tarkiainen J, Halldin C, Sóvagó J, Gulyas B, Wikström HV, Farde L.
    Mol Imaging Biol; 2005 Feb; 7(3):209-19. PubMed ID: 15912425
    [Abstract] [Full Text] [Related]

  • 6. Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man.
    Farde L, Ito H, Swahn CG, Pike VW, Halldin C.
    J Nucl Med; 1998 Nov; 39(11):1965-71. PubMed ID: 9829590
    [Abstract] [Full Text] [Related]

  • 7. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain.
    Andrée B, Halldin C, Pike VW, Gunn RN, Olsson H, Farde L.
    J Nucl Med; 2002 Mar; 43(3):292-303. PubMed ID: 11884487
    [Abstract] [Full Text] [Related]

  • 8. Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11 C]WAY-100635.
    Pike VW, McCarron JA, Lammertsma AA, Osman S, Hume SP, Sargent PA, Bench CJ, Cliffe IA, Fletcher A, Grasby PM.
    Eur J Pharmacol; 1996 Apr 22; 301(1-3):R5-7. PubMed ID: 8773468
    [Abstract] [Full Text] [Related]

  • 9. The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo.
    McCarron JA, Pike VW, Halldin C, Sandell J, Sóvágó J, Gulyas B, Cselényi Z, Wikström HV, Marchais-Oberwinkler S, Nowicki B, Dollé F, Farde L.
    Mol Imaging Biol; 2004 Apr 22; 6(1):17-26. PubMed ID: 15018825
    [Abstract] [Full Text] [Related]

  • 10. PET-characterization of [carbonyl-11C]WAY-100635 binding to 5-HT1A receptors in the primate brain.
    Farde L, Ginovart N, Ito H, Lundkvist C, Pike VW, McCarron JA, Halldin C.
    Psychopharmacology (Berl); 1997 Sep 22; 133(2):196-202. PubMed ID: 9342787
    [Abstract] [Full Text] [Related]

  • 11. Development of fluorine-18-labeled 5-HT1A antagonists.
    Lang L, Jagoda E, Schmall B, Vuong BK, Adams HR, Nelson DL, Carson RE, Eckelman WC.
    J Med Chem; 1999 May 06; 42(9):1576-86. PubMed ID: 10229627
    [Abstract] [Full Text] [Related]

  • 12. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.
    Marchais-Oberwinkler S, Nowicki B, Pike VW, Halldin C, Sandell J, Chou YH, Gulyas B, Brennum LT, Farde L, Wikström HV.
    Bioorg Med Chem; 2005 Feb 01; 13(3):883-93. PubMed ID: 15653354
    [Abstract] [Full Text] [Related]

  • 13. Imaging 5-HT1A receptors with positron emission tomography: initial human studies with [11C]CPC-222.
    Houle S, Wilson AA, Inaba T, Fisher N, DaSilva JN.
    Nucl Med Commun; 1997 Dec 01; 18(12):1130-4. PubMed ID: 9481759
    [Abstract] [Full Text] [Related]

  • 14. Localization of 5-HT1A receptors in the living human brain using [carbonyl-11C]WAY-100635: PET with anatomic standardization technique.
    Ito H, Halldin C, Farde L.
    J Nucl Med; 1999 Jan 01; 40(1):102-9. PubMed ID: 9935065
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate.
    Saigal N, Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.
    J Nucl Med; 2006 Oct 01; 47(10):1697-706. PubMed ID: 17015907
    [Abstract] [Full Text] [Related]

  • 16. Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635.
    Hall H, Lundkvist C, Halldin C, Farde L, Pike VW, McCarron JA, Fletcher A, Cliffe IA, Barf T, Wikström H, Sedvall G.
    Brain Res; 1997 Jan 16; 745(1-2):96-108. PubMed ID: 9037397
    [Abstract] [Full Text] [Related]

  • 17. Quantification of serotonin 5-HT1A receptors in monkey brain with [11C](R)-(-)-RWAY.
    Yasuno F, Zoghbi SS, McCarron JA, Hong J, Ichise M, Brown AK, Gladding RL, Bacher JD, Pike VW, Innis RB.
    Synapse; 2006 Dec 01; 60(7):510-20. PubMed ID: 16952161
    [Abstract] [Full Text] [Related]

  • 18. PET-examination and metabolite evaluation in monkey of [(11)C]NAD-299, a radioligand for visualisation of the 5-HT(1A) receptor.
    Sandell J, Halldin C, Chou YH, Swahn CG, Thorberg SO, Farde L.
    Nucl Med Biol; 2002 Jan 01; 29(1):39-45. PubMed ID: 11786274
    [Abstract] [Full Text] [Related]

  • 19. Evaluation of [O-methyl-3H]WAY-100635 as an in vivo radioligand for 5-HT1A receptors in rat brain.
    Hume SP, Ashworth S, Opacka-Juffry J, Ahier RG, Lammertsma AA, Pike VW, Cliffe IA, Fletcher A, White AC.
    Eur J Pharmacol; 1994 Dec 27; 271(2-3):515-23. PubMed ID: 7705452
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET.
    McCarron JA, Zoghbi SS, Shetty HU, Vermeulen ES, Wikström HV, Ichise M, Yasuno F, Halldin C, Innis RB, Pike VW.
    Eur J Nucl Med Mol Imaging; 2007 Oct 27; 34(10):1670-82. PubMed ID: 17579853
    [Abstract] [Full Text] [Related]


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