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Journal Abstract Search

150 related items for PubMed ID: 9632373

  • 1.
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  • 2. Cyclic HIV protease inhibitors: design and synthesis of orally bioavailable, pyrazole P2/P2' cyclic ureas with improved potency.
    Han Q, Chang CH, Li R, Ru Y, Jadhav PK, Lam PY.
    J Med Chem; 1998 Jun 04; 41(12):2019-28. PubMed ID: 9622543
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  • 5. Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors.
    Rodgers JD, Lam PY, Johnson BL, Wang H, Li R, Ru Y, Ko SS, Seitz SP, Trainor GL, Anderson PS, Klabe RM, Bacheler LT, Cordova B, Garber S, Reid C, Wright MR, Chang CH, Erickson-Viitanen S.
    Chem Biol; 1998 Oct 04; 5(10):597-608. PubMed ID: 9818151
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  • 8. Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency.
    Klabe RM, Bacheler LT, Ala PJ, Erickson-Viitanen S, Meek JL.
    Biochemistry; 1998 Jun 16; 37(24):8735-42. PubMed ID: 9628735
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  • 9. Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.
    Jadhav PK, Ala P, Woerner FJ, Chang CH, Garber SS, Anton ED, Bacheler LT.
    J Med Chem; 1997 Jan 17; 40(2):181-91. PubMed ID: 9003516
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  • 10. Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.
    Ala PJ, Huston EE, Klabe RM, McCabe DD, Duke JL, Rizzo CJ, Korant BD, DeLoskey RJ, Lam PY, Hodge CN, Chang CH.
    Biochemistry; 1997 Feb 18; 36(7):1573-80. PubMed ID: 9048541
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  • 12. Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas.
    Lam PY, Ru Y, Jadhav PK, Aldrich PE, DeLucca GV, Eyermann CJ, Chang CH, Emmett G, Holler ER, Daneker WF, Li L, Confalone PN, McHugh RJ, Han Q, Li R, Markwalder JA, Seitz SP, Sharpe TR, Bacheler LT, Rayner MM, Klabe RM, Shum L, Winslow DL, Kornhauser DM, Hodge CN.
    J Med Chem; 1996 Aug 30; 39(18):3514-25. PubMed ID: 8784449
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  • 14. Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: novel biaryl indazoles as P2/P2' substituents.
    Patel M, Rodgers JD, McHugh RJ, Johnson BL, Cordova BC, Klabe RM, Bacheler LT, Erickson-Viitanen S, Ko SS.
    Bioorg Med Chem Lett; 1999 Nov 15; 9(22):3217-20. PubMed ID: 10576691
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  • 16. Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure-activity relationships, and X-ray crystal structure studies.
    Jadhav PK, Woerner FJ, Lam PY, Hodge CN, Eyermann CJ, Man HW, Daneker WF, Bacheler LT, Rayner MM, Meek JL, Erickson-Viitanen S, Jackson DA, Calabrese JC, Schadt M, Chang CH.
    J Med Chem; 1998 Apr 23; 41(9):1446-55. PubMed ID: 9554878
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  • 17. Nonsymmetrically substituted cyclic urea HIV protease inhibitors.
    Wilkerson WW, Dax S, Cheatham WW.
    J Med Chem; 1997 Dec 05; 40(25):4079-88. PubMed ID: 9406598
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  • 18. Potent inhibitors of the HIV-1 protease incorporating cyclic urea P1-P2 scaffold.
    Kazmierski WM, Furfine E, Gray-Nunez Y, Spaltenstein A, Wright L.
    Bioorg Med Chem Lett; 2004 Nov 15; 14(22):5685-7. PubMed ID: 15482948
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  • 20. Synthesis, antiviral activity and pharmacokinetics of P1/P1' substituted 3-aminoindazole cyclic urea HIV protease inhibitors.
    Kaltenbach RF, Patel M, Waltermire RE, Harris GD, Stone BR, Klabe RM, Garber S, Bacheler LT, Cordova BC, Logue K, Wright MR, Erickson-Viitanen S, Trainor GL.
    Bioorg Med Chem Lett; 2003 Feb 24; 13(4):605-8. PubMed ID: 12639540
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