These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

368 related items for PubMed ID: 9639573

  • 1. cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.
    Hoffmann R, Wilkinson IR, McCallum JF, Engels P, Houslay MD.
    Biochem J; 1998 Jul 01; 333 ( Pt 1)(Pt 1):139-49. PubMed ID: 9639573
    [Abstract] [Full Text] [Related]

  • 2. Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).
    MacKenzie SJ, Baillie GS, McPhee I, MacKenzie C, Seamons R, McSorley T, Millen J, Beard MB, van Heeke G, Houslay MD.
    Br J Pharmacol; 2002 Jun 01; 136(3):421-33. PubMed ID: 12023945
    [Abstract] [Full Text] [Related]

  • 3. Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation.
    Sette C, Conti M.
    J Biol Chem; 1996 Jul 12; 271(28):16526-34. PubMed ID: 8663227
    [Abstract] [Full Text] [Related]

  • 4. Identification of inhibitor binding sites of the cAMP-specific phosphodiesterase 4.
    Richter W, Unciuleac L, Hermsdorf T, Kronbach T, Dettmer D.
    Cell Signal; 2001 Apr 12; 13(4):287-97. PubMed ID: 11306246
    [Abstract] [Full Text] [Related]

  • 5. Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition.
    McPhee I, Yarwood SJ, Scotland G, Huston E, Beard MB, Ross AH, Houslay ES, Houslay MD.
    J Biol Chem; 1999 Apr 23; 274(17):11796-810. PubMed ID: 10206997
    [Abstract] [Full Text] [Related]

  • 6. In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
    McCahill A, McSorley T, Huston E, Hill EV, Lynch MJ, Gall I, Keryer G, Lygren B, Tasken K, van Heeke G, Houslay MD.
    Cell Signal; 2005 Sep 23; 17(9):1158-73. PubMed ID: 15905070
    [Abstract] [Full Text] [Related]

  • 7. Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene.
    Bolger GB, Erdogan S, Jones RE, Loughney K, Scotland G, Hoffmann R, Wilkinson I, Farrell C, Houslay MD.
    Biochem J; 1997 Dec 01; 328 ( Pt 2)(Pt 2):539-48. PubMed ID: 9371713
    [Abstract] [Full Text] [Related]

  • 8. The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.
    Hoffmann R, Baillie GS, MacKenzie SJ, Yarwood SJ, Houslay MD.
    EMBO J; 1999 Feb 15; 18(4):893-903. PubMed ID: 10022832
    [Abstract] [Full Text] [Related]

  • 9. Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells.
    Zhu B, Kelly J, Vemavarapu L, Thompson WJ, Strada SJ.
    Biochem Pharmacol; 2004 Aug 01; 68(3):479-91. PubMed ID: 15242814
    [Abstract] [Full Text] [Related]

  • 10. Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.
    Huston E, Lumb S, Russell A, Catterall C, Ross AH, Steele MR, Bolger GB, Perry MJ, Owens RJ, Houslay MD.
    Biochem J; 1997 Dec 01; 328 ( Pt 2)(Pt 2):549-58. PubMed ID: 9371714
    [Abstract] [Full Text] [Related]

  • 11. Human phosphodiesterase 4A: characterization of full-length and truncated enzymes expressed in COS cells.
    Owens RJ, Catterall C, Batty D, Jappy J, Russell A, Smith B, O'Connell J, Perry MJ.
    Biochem J; 1997 Aug 15; 326 ( Pt 1)(Pt 1):53-60. PubMed ID: 9337850
    [Abstract] [Full Text] [Related]

  • 12. Phorbol 12-myristate 13-acetate triggers the protein kinase A-mediated phosphorylation and activation of the PDE4D5 cAMP phosphodiesterase in human aortic smooth muscle cells through a route involving extracellular signal regulated kinase (ERK).
    Baillie G, MacKenzie SJ, Houslay MD.
    Mol Pharmacol; 2001 Nov 15; 60(5):1100-11. PubMed ID: 11641439
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14. Oxidative stress employs phosphatidyl inositol 3-kinase and ERK signalling pathways to activate cAMP phosphodiesterase-4D3 (PDE4D3) through multi-site phosphorylation at Ser239 and Ser579.
    Hill EV, Sheppard CL, Cheung YF, Gall I, Krause E, Houslay MD.
    Cell Signal; 2006 Nov 15; 18(11):2056-69. PubMed ID: 16973330
    [Abstract] [Full Text] [Related]

  • 15. Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process.
    Terry R, Cheung YF, Praestegaard M, Baillie GS, Huston E, Gall I, Adams DR, Houslay MD.
    Cell Signal; 2003 Oct 15; 15(10):955-71. PubMed ID: 12873709
    [Abstract] [Full Text] [Related]

  • 16. Salbutamol up-regulates PDE4 activity and induces a heterologous desensitization of U937 cells to prostaglandin E2. Implications for the therapeutic use of beta-adrenoceptor agonists.
    Torphy TJ, Zhou HL, Foley JJ, Sarau HM, Manning CD, Barnette MS.
    J Biol Chem; 1995 Oct 06; 270(40):23598-604. PubMed ID: 7559525
    [Abstract] [Full Text] [Related]

  • 17. Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells.
    Stefan E, Wiesner B, Baillie GS, Mollajew R, Henn V, Lorenz D, Furkert J, Santamaria K, Nedvetsky P, Hundsrucker C, Beyermann M, Krause E, Pohl P, Gall I, MacIntyre AN, Bachmann S, Houslay MD, Rosenthal W, Klussmann E.
    J Am Soc Nephrol; 2007 Jan 06; 18(1):199-212. PubMed ID: 17135396
    [Abstract] [Full Text] [Related]

  • 18.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 19. The oligomerization state determines regulatory properties and inhibitor sensitivity of type 4 cAMP-specific phosphodiesterases.
    Richter W, Conti M.
    J Biol Chem; 2004 Jul 16; 279(29):30338-48. PubMed ID: 15131123
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain.
    Iona S, Cuomo M, Bushnik T, Naro F, Sette C, Hess M, Shelton ER, Conti M.
    Mol Pharmacol; 1998 Jan 16; 53(1):23-32. PubMed ID: 9443929
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 19.