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Journal Abstract Search

258 related items for PubMed ID: 9642078

  • 21. Specificity and affinity motifs for Grb2 SH2-ligand interactions.
    Kessels HW, Ward AC, Schumacher TN.
    Proc Natl Acad Sci U S A; 2002 Jun 25; 99(13):8524-9. PubMed ID: 12084912
    [Abstract] [Full Text] [Related]

  • 22. Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain.
    Thornton KH, Mueller WT, McConnell P, Zhu G, Saltiel AR, Thanabal V.
    Biochemistry; 1996 Sep 10; 35(36):11852-64. PubMed ID: 8794768
    [Abstract] [Full Text] [Related]

  • 23. Crystal structure of the C-terminal SH2 domain of the p85alpha regulatory subunit of phosphoinositide 3-kinase: an SH2 domain mimicking its own substrate.
    Hoedemaeker FJ, Siegal G, Roe SM, Driscoll PC, Abrahams JP.
    J Mol Biol; 1999 Oct 01; 292(4):763-70. PubMed ID: 10525402
    [Abstract] [Full Text] [Related]

  • 24. Surface plasmon resonance thermodynamic and kinetic analysis as a strategic tool in drug design. Distinct ways for phosphopeptides to plug into Src- and Grb2 SH2 domains.
    de Mol NJ, Dekker FJ, Broutin I, Fischer MJ, Liskamp RM.
    J Med Chem; 2005 Feb 10; 48(3):753-63. PubMed ID: 15689159
    [Abstract] [Full Text] [Related]

  • 25. Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase.
    Bradshaw JM, Mitaxov V, Waksman G.
    J Mol Biol; 1999 Nov 05; 293(4):971-85. PubMed ID: 10543978
    [Abstract] [Full Text] [Related]

  • 26. Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides.
    Lee K, Zhang M, Liu H, Yang D, Burke TR.
    J Med Chem; 2003 Jun 19; 46(13):2621-30. PubMed ID: 12801226
    [Abstract] [Full Text] [Related]

  • 27. Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
    Zhou MM, Ravichandran KS, Olejniczak EF, Petros AM, Meadows RP, Sattler M, Harlan JE, Wade WS, Burakoff SJ, Fesik SW.
    Nature; 1995 Dec 07; 378(6557):584-92. PubMed ID: 8524391
    [Abstract] [Full Text] [Related]

  • 28. Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface.
    Lubman OY, Waksman G.
    J Mol Biol; 2002 Feb 15; 316(2):291-304. PubMed ID: 11851339
    [Abstract] [Full Text] [Related]

  • 29. Solution structure of Grb2 reveals extensive flexibility necessary for target recognition.
    Yuzawa S, Yokochi M, Hatanaka H, Ogura K, Kataoka M, Miura K, Mandiyan V, Schlessinger J, Inagaki F.
    J Mol Biol; 2001 Feb 23; 306(3):527-37. PubMed ID: 11178911
    [Abstract] [Full Text] [Related]

  • 30. Structural requirements for Tyr in the consensus sequence Y-E-N of a novel nonphosphorylated inhibitor to the Grb2-SH2 domain.
    Long YQ, Yao ZJ, Voigt JH, Lung FD, Luo JH, Burke TR, King CR, Yang D, Roller PP.
    Biochem Biophys Res Commun; 1999 Nov 02; 264(3):902-8. PubMed ID: 10544028
    [Abstract] [Full Text] [Related]

  • 31. Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity.
    Shi ZD, Liu H, Zhang M, Worthy KM, Bindu L, Yang D, Fisher RJ, Burke TR.
    Bioorg Med Chem; 2005 Jul 01; 13(13):4200-8. PubMed ID: 15893931
    [Abstract] [Full Text] [Related]

  • 32. Alternative mode of binding to phosphotyrosyl peptides by Src homology-2 domains.
    Qin C, Wavreille AS, Pei D.
    Biochemistry; 2005 Sep 13; 44(36):12196-202. PubMed ID: 16142918
    [Abstract] [Full Text] [Related]

  • 33. Molecular dynamics, free energy, and SPR analyses of the interactions between the SH2 domain of Grb2 and ErbB phosphotyrosyl peptides.
    Suenaga A, Hatakeyama M, Ichikawa M, Yu X, Futatsugi N, Narumi T, Fukui K, Terada T, Taiji M, Shirouzu M, Yokoyama S, Konagaya A.
    Biochemistry; 2003 May 13; 42(18):5195-200. PubMed ID: 12731860
    [Abstract] [Full Text] [Related]

  • 34. Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: a thermodynamic study.
    Bradshaw JM, Grucza RA, Ladbury JE, Waksman G.
    Biochemistry; 1998 Jun 23; 37(25):9083-90. PubMed ID: 9636054
    [Abstract] [Full Text] [Related]

  • 35. Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain.
    Liu WQ, Vidal M, Gresh N, Roques BP, Garbay C.
    J Med Chem; 1999 Sep 09; 42(18):3737-41. PubMed ID: 10479306
    [Abstract] [Full Text] [Related]

  • 36. Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.
    Boerner JL, Danielsen AJ, Lovejoy CA, Wang Z, Juneja SC, Faupel-Badger JM, Darce JR, Maihle NJ.
    Oncogene; 2003 Oct 02; 22(43):6679-89. PubMed ID: 14555981
    [Abstract] [Full Text] [Related]

  • 37. Phosphopeptide ligands of the SHP-1 N-SH2 domain: effects on binding and stimulation of phosphatase activity.
    Hampel K, Kaufhold I, Zacharias M, Böhmer FD, Imhof D.
    ChemMedChem; 2006 Aug 02; 1(8):869-77. PubMed ID: 16902940
    [Abstract] [Full Text] [Related]

  • 38. Potent antagonists of the SH2 domain of Grb2: optimization of the X+1 position of 3-amino-Z-Tyr(PO3H2)-X+1-Asn-NH2.
    García-Echeverría C, Furet P, Gay B, Fretz H, Rahuel J, Schoepfer J, Caravatti G.
    J Med Chem; 1998 May 21; 41(11):1741-4. PubMed ID: 9599224
    [No Abstract] [Full Text] [Related]

  • 39. Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1.
    Imhof D, Wieligmann K, Hampel K, Nothmann D, Zoda MS, Schmidt-Arras D, Zacharias M, Böhmer FD, Reissmann S.
    J Med Chem; 2005 Mar 10; 48(5):1528-39. PubMed ID: 15743195
    [Abstract] [Full Text] [Related]

  • 40. Crystal structure of the SH2 domain from the adaptor protein SHC: a model for peptide binding based on X-ray and NMR data.
    Mikol V, Baumann G, Zurini MG, Hommel U.
    J Mol Biol; 1995 Nov 17; 254(1):86-95. PubMed ID: 7473762
    [Abstract] [Full Text] [Related]

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