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Journal Abstract Search

57 related items for PubMed ID: 9652956

  • 1. [Biochemistry of presenilin 1].
    Takashima A.
    Rinsho Shinkeigaku; 1997 Dec; 37(12):1097-8. PubMed ID: 9652956
    [Abstract] [Full Text] [Related]

  • 2. Localization of Alzheimer-associated presenilin 1 in transfected COS-7 cells.
    Takashima A, Sato M, Mercken M, Tanaka S, Kondo S, Honda T, Sato K, Murayama M, Noguchi K, Nakazato Y, Takahashi H.
    Biochem Biophys Res Commun; 1996 Oct 14; 227(2):423-6. PubMed ID: 8878531
    [Abstract] [Full Text] [Related]

  • 3. Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.
    Mercken M, Takahashi H, Honda T, Sato K, Murayama M, Nakazato Y, Noguchi K, Imahori K, Takashima A.
    FEBS Lett; 1996 Jul 08; 389(3):297-303. PubMed ID: 8766720
    [Abstract] [Full Text] [Related]

  • 4. Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
    Podlisny MB, Citron M, Amarante P, Sherrington R, Xia W, Zhang J, Diehl T, Levesque G, Fraser P, Haass C, Koo EH, Seubert P, St George-Hyslop P, Teplow DB, Selkoe DJ.
    Neurobiol Dis; 1997 Jul 08; 3(4):325-37. PubMed ID: 9173929
    [Abstract] [Full Text] [Related]

  • 5. Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.
    Citron M, Eckman CB, Diehl TS, Corcoran C, Ostaszewski BL, Xia W, Levesque G, St George Hyslop P, Younkin SG, Selkoe DJ.
    Neurobiol Dis; 1998 Aug 08; 5(2):107-16. PubMed ID: 9746908
    [Abstract] [Full Text] [Related]

  • 6. Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.
    Levey AI, Heilman CJ, Lah JJ, Nash NR, Rees HD, Wakai M, Mirra SS, Rye DB, Nochlin D, Bird TD, Mufson EJ.
    Ann Neurol; 1997 Jun 08; 41(6):742-53. PubMed ID: 9189035
    [Abstract] [Full Text] [Related]

  • 7. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
    [Abstract] [Full Text] [Related]

  • 8. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
    [Abstract] [Full Text] [Related]

  • 9. Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane.
    Uemura K, Kitagawa N, Kohno R, Kuzuya A, Kageyama T, Chonabayashi K, Shibasaki H, Shimohama S.
    J Neurosci Res; 2003 Oct 15; 74(2):184-91. PubMed ID: 14515347
    [Abstract] [Full Text] [Related]

  • 10. Mapping the APP/presenilin (PS) binding domains: the hydrophilic N-terminus of PS2 is sufficient for interaction with APP and can displace APP/PS1 interaction.
    Pradier L, Carpentier N, Delalonde L, Clavel N, Bock MD, Buée L, Mercken L, Tocqué B, Czech C.
    Neurobiol Dis; 1999 Feb 15; 6(1):43-55. PubMed ID: 10078972
    [Abstract] [Full Text] [Related]

  • 11. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 15; 1(8):479-85. PubMed ID: 10587643
    [Abstract] [Full Text] [Related]

  • 12. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
    Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA.
    Exp Neurol; 2004 Aug 15; 188(2):224-37. PubMed ID: 15246822
    [Abstract] [Full Text] [Related]

  • 13. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.
    Li YM, Xu M, Lai MT, Huang Q, Castro JL, DiMuzio-Mower J, Harrison T, Lellis C, Nadin A, Neduvelil JG, Register RB, Sardana MK, Shearman MS, Smith AL, Shi XP, Yin KC, Shafer JA, Gardell SJ.
    Nature; 2000 Jun 08; 405(6787):689-94. PubMed ID: 10864326
    [Abstract] [Full Text] [Related]

  • 14. FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: evidence for direct involvement of PS1 in the gamma-secretase cleavage complex.
    Xia W, Ostaszewski BL, Kimberly WT, Rahmati T, Moore CL, Wolfe MS, Selkoe DJ.
    Neurobiol Dis; 2000 Dec 08; 7(6 Pt B):673-81. PubMed ID: 11114265
    [Abstract] [Full Text] [Related]

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  • 16. The presenilin 1 C92S mutation increases abeta 42 production.
    Lewis PA, Perez-Tur J, Golde TE, Hardy J.
    Biochem Biophys Res Commun; 2000 Oct 14; 277(1):261-3. PubMed ID: 11027672
    [Abstract] [Full Text] [Related]

  • 17. Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk, in stable transfectants expressing presenilin 1 protein.
    Hamano T, Mutoh T, Tabira T, Araki W, Kuriyama M, Mihara T, Yano S, Yamamoto H.
    Brain Res Mol Brain Res; 2005 Jun 13; 137(1-2):70-6. PubMed ID: 15950763
    [Abstract] [Full Text] [Related]

  • 18. The coat protein complex II, COPII, protein Sec13 directly interacts with presenilin-1.
    Nielsen AL.
    Biochem Biophys Res Commun; 2009 Oct 23; 388(3):571-5. PubMed ID: 19682973
    [Abstract] [Full Text] [Related]

  • 19. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
    Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G.
    Nat Cell Biol; 2000 Dec 23; 2(12):863-70. PubMed ID: 11146649
    [Abstract] [Full Text] [Related]

  • 20. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES, Martinez M, Brunkan AL, Goate A.
    J Neurochem; 2005 Jan 23; 92(2):294-301. PubMed ID: 15663477
    [Abstract] [Full Text] [Related]

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