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967 related items for PubMed ID: 9653127

  • 1. Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway.
    Huang LE, Gu J, Schau M, Bunn HF.
    Proc Natl Acad Sci U S A; 1998 Jul 07; 95(14):7987-92. PubMed ID: 9653127
    [Abstract] [Full Text] [Related]

  • 2. Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway.
    Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L.
    J Biol Chem; 1999 Mar 05; 274(10):6519-25. PubMed ID: 10037745
    [Abstract] [Full Text] [Related]

  • 3. Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes.
    Salceda S, Caro J.
    J Biol Chem; 1997 Sep 05; 272(36):22642-7. PubMed ID: 9278421
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.
    Tanimoto K, Makino Y, Pereira T, Poellinger L.
    EMBO J; 2000 Aug 15; 19(16):4298-309. PubMed ID: 10944113
    [Abstract] [Full Text] [Related]

  • 5. Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins.
    Srinivas V, Zhang LP, Zhu XH, Caro J.
    Biochem Biophys Res Commun; 1999 Jul 05; 260(2):557-61. PubMed ID: 10403805
    [Abstract] [Full Text] [Related]

  • 6. Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7.
    Cho S, Choi YJ, Kim JM, Jeong ST, Kim JH, Kim SH, Ryu SE.
    FEBS Lett; 2001 Jun 01; 498(1):62-6. PubMed ID: 11389899
    [Abstract] [Full Text] [Related]

  • 7. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
    Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH.
    J Biol Chem; 2000 Aug 18; 275(33):25733-41. PubMed ID: 10823831
    [Abstract] [Full Text] [Related]

  • 8. HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation.
    Berra E, Richard DE, Gothié E, Pouysségur J.
    FEBS Lett; 2001 Feb 23; 491(1-2):85-90. PubMed ID: 11226425
    [Abstract] [Full Text] [Related]

  • 9. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
    Mole DR, Maxwell PH, Pugh CW, Ratcliffe PJ.
    IUBMB Life; 2001 Jul 23; 52(1-2):43-7. PubMed ID: 11795592
    [Abstract] [Full Text] [Related]

  • 10. Activation of hypoxia-induced transcription in normoxia.
    Hägg M, Wennström S.
    Exp Cell Res; 2005 May 15; 306(1):180-91. PubMed ID: 15878343
    [Abstract] [Full Text] [Related]

  • 11. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
    Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ.
    Nature; 1999 May 20; 399(6733):271-5. PubMed ID: 10353251
    [Abstract] [Full Text] [Related]

  • 12. Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor.
    Kallio PJ, Pongratz I, Gradin K, McGuire J, Poellinger L.
    Proc Natl Acad Sci U S A; 1997 May 27; 94(11):5667-72. PubMed ID: 9159130
    [Abstract] [Full Text] [Related]

  • 13. Cadmium blocks hypoxia-inducible factor (HIF)-1-mediated response to hypoxia by stimulating the proteasome-dependent degradation of HIF-1alpha.
    Chun YS, Choi E, Kim GT, Choi H, Kim CH, Lee MJ, Kim MS, Park JW.
    Eur J Biochem; 2000 Jul 27; 267(13):4198-204. PubMed ID: 10866824
    [Abstract] [Full Text] [Related]

  • 14. Hypoxia-inducible factor 1alpha (HIF-1alpha) is a non-heme iron protein. Implications for oxygen sensing.
    Srinivas V, Zhu X, Salceda S, Nakamura R, Caro J.
    J Biol Chem; 1998 Jul 17; 273(29):18019-22. PubMed ID: 9660756
    [Abstract] [Full Text] [Related]

  • 15. Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension.
    Jiang BH, Zheng JZ, Leung SW, Roe R, Semenza GL.
    J Biol Chem; 1997 Aug 01; 272(31):19253-60. PubMed ID: 9235919
    [Abstract] [Full Text] [Related]

  • 16. Structural and functional analysis of hypoxia-inducible factor 1.
    Semenza GL, Agani F, Booth G, Forsythe J, Iyer N, Jiang BH, Leung S, Roe R, Wiener C, Yu A.
    Kidney Int; 1997 Feb 01; 51(2):553-5. PubMed ID: 9027737
    [Abstract] [Full Text] [Related]

  • 17. Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha.
    Hur E, Chang KY, Lee E, Lee SK, Park H.
    Mol Pharmacol; 2001 May 01; 59(5):1216-24. PubMed ID: 11306706
    [Abstract] [Full Text] [Related]

  • 18. Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha.
    Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L.
    EMBO J; 1998 Nov 16; 17(22):6573-86. PubMed ID: 9822602
    [Abstract] [Full Text] [Related]

  • 19. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1.
    Jiang BH, Rue E, Wang GL, Roe R, Semenza GL.
    J Biol Chem; 1996 Jul 26; 271(30):17771-8. PubMed ID: 8663540
    [Abstract] [Full Text] [Related]

  • 20. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit.
    Huang LE, Arany Z, Livingston DM, Bunn HF.
    J Biol Chem; 1996 Dec 13; 271(50):32253-9. PubMed ID: 8943284
    [Abstract] [Full Text] [Related]

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