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285 related items for PubMed ID: 9658187

  • 1. Photoaffinity labeling of the benzodiazepine binding site of alpha1beta3gamma2 gamma-aminobutyric acidA receptors with flunitrazepam identifies a subset of ligands that interact directly with His102 of the alpha subunit and predicts orientation of these within the benzodiazepine pharmacophore.
    McKernan RM, Farrar S, Collins I, Emms F, Asuni A, Quirk K, Broughton H.
    Mol Pharmacol; 1998 Jul; 54(1):33-43. PubMed ID: 9658187
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  • 2. Key amino acids in the gamma subunit of the gamma-aminobutyric acidA receptor that determine ligand binding and modulation at the benzodiazepine site.
    Wingrove PB, Thompson SA, Wafford KA, Whiting PJ.
    Mol Pharmacol; 1997 Nov; 52(5):874-81. PubMed ID: 9351978
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  • 3. Role of the histidine residue at position 105 in the human alpha 5 containing GABA(A) receptor on the affinity and efficacy of benzodiazepine site ligands.
    Kelly MD, Smith A, Banks G, Wingrove P, Whiting PW, Atack J, Seabrook GR, Maubach KA.
    Br J Pharmacol; 2002 Jan; 135(1):248-56. PubMed ID: 11786501
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  • 4. Flunitrazepam photoaffinity labeling of the GABA(A) receptor reduces inhibition of [3H]Ro15-4513 binding by GABA.
    Borden LA, Gibbs TT.
    Eur J Pharmacol; 1990 Jun 12; 188(6):391-7. PubMed ID: 2164940
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  • 8. An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.
    Clayton T, Chen JL, Ernst M, Richter L, Cromer BA, Morton CJ, Ng H, Kaczorowski CC, Helmstetter FJ, Furtmüller R, Ecker G, Parker MW, Sieghart W, Cook JM.
    Curr Med Chem; 2007 Jun 12; 14(26):2755-75. PubMed ID: 18045122
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  • 13. Characterization of a benzodiazepine receptor site with exceptionally high affinity for Ro 15-4513 in the rat CNS.
    Mehta AK, Shank RP.
    Brain Res; 1995 Dec 18; 704(2):289-97. PubMed ID: 8788925
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  • 14. Central benzodiazepine receptors: in vitro efficacies and potencies of 3-substituted 1,4-benzodiazepine stereoisomers.
    Maksay G, Tegyey Z, Simonyi M.
    Mol Pharmacol; 1991 Jun 18; 39(6):725-32. PubMed ID: 1646947
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  • 15. Deduction of amino acid residues in the GABA(A) receptor alpha subunits photoaffinity labeled with the benzodiazepine flunitrazepam.
    Smith GB, Olsen RW.
    Neuropharmacology; 2000 Jun 18; 39(1):55-64. PubMed ID: 10665819
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  • 16. [3H]RY 80: A high-affinity, selective ligand for gamma-aminobutyric acidA receptors containing alpha-5 subunits.
    Skolnick P, Hu RJ, Cook CM, Hurt SD, Trometer JD, Liu R, Huang Q, Cook JM.
    J Pharmacol Exp Ther; 1997 Nov 18; 283(2):488-93. PubMed ID: 9353361
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  • 17. Comparison of interactions of [3H]muscimol, t-butylbicyclophosphoro[35S]thionate, and [3H]flunitrazepam with cloned gamma-aminobutyric acidA receptors of the alpha 1 beta 2 and alpha 1 beta 2 gamma 2 subtypes.
    Pregenzer JF, Im WB, Carter DB, Thomsen DR.
    Mol Pharmacol; 1993 May 18; 43(5):801-6. PubMed ID: 8388991
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  • 18. Mapping the benzodiazepine photoaffinity-labelling site with sequence-specific gamma-aminobutyric acidA-receptor antibodies.
    Stephenson FA, Duggan MJ.
    Biochem J; 1989 Nov 15; 264(1):199-206. PubMed ID: 2557827
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  • 19. Chronic exposure of cells expressing recombinant GABAA receptors to benzodiazepine antagonist flumazenil enhances the maximum number of benzodiazepine binding sites.
    Pericić D, Lazić J, Jembrek MJ, Strac DS, Rajcan I.
    Life Sci; 2004 Dec 03; 76(3):303-17. PubMed ID: 15531382
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  • 20. Functional modulation of cerebral gamma-aminobutyric acidA receptor/benzodiazepine receptor/chloride ion channel complex with ethyl beta-carboline-3-carboxylate: presence of independent binding site for ethyl beta-carboline-3-carboxylate.
    Taguchi J, Kuriyama K.
    J Pharmacol Exp Ther; 1990 May 03; 253(2):558-66. PubMed ID: 2159999
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