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253 related items for PubMed ID: 9658199

  • 1. Identification of a [3H]Ligand for the common allosteric site of muscarinic acetylcholine M2 receptors.
    Tränkle C, Mies-Klomfass E, Cid MH, Holzgrabe U, Mohr K.
    Mol Pharmacol; 1998 Jul; 54(1):139-45. PubMed ID: 9658199
    [Abstract] [Full Text] [Related]

  • 2. Using a radioalloster to test predictions of the cooperativity model for gallamine binding to the allosteric site of muscarinic acetylcholine M(2) receptors.
    Tränkle C, Weyand O, Schröter A, Mohr K.
    Mol Pharmacol; 1999 Nov; 56(5):962-5. PubMed ID: 10531401
    [Abstract] [Full Text] [Related]

  • 3. Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors.
    Tränkle C, Weyand O, Voigtländer U, Mynett A, Lazareno S, Birdsall NJ, Mohr K.
    Mol Pharmacol; 2003 Jul; 64(1):180-90. PubMed ID: 12815174
    [Abstract] [Full Text] [Related]

  • 4. Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist.
    Grossmüller M, Antony J, Tränkle C, Holzgrabe U, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Jan; 372(4):267-76. PubMed ID: 16362429
    [Abstract] [Full Text] [Related]

  • 5. Testing the specificity of allosteric modulators of muscarinic receptors in phylogenetically closely related histamine H1-receptors.
    Franken C, Tränkle C, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Feb; 361(2):107-12. PubMed ID: 10685864
    [Abstract] [Full Text] [Related]

  • 6. Interaction of Mg2+ with the allosteric site of muscarinic M2 receptors.
    Burgmer U, Schulz U, Tränkle C, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Apr; 357(4):363-70. PubMed ID: 9606020
    [Abstract] [Full Text] [Related]

  • 7. Allosteric stabilization of 3H-N-methylscopolamine binding in guinea-pig myocardium by an antidote against organophosphate intoxication.
    Jepsen K, Lüllmann H, Mohr K, Pfeffer J.
    Pharmacol Toxicol; 1988 Sep; 63(3):163-8. PubMed ID: 3054859
    [Abstract] [Full Text] [Related]

  • 8. M2 receptor binding of the selective antagonist AF-DX 384: possible involvement of the common allosteric site.
    Tränkle C, Andresen I, Lambrecht G, Mohr K.
    Mol Pharmacol; 1998 Feb; 53(2):304-12. PubMed ID: 9463489
    [Abstract] [Full Text] [Related]

  • 9. Divergent modes of action among cationic allosteric modulators of muscarinic M2 receptors.
    Tränkle C, Mohr K.
    Mol Pharmacol; 1997 Apr; 51(4):674-82. PubMed ID: 9106634
    [Abstract] [Full Text] [Related]

  • 10. Modes of allosteric interactions with free and [3H]N-methylscopolamine-occupied muscarinic M2 receptors as deduced from buffer-dependent potency shifts.
    Schröter A, Tränkle C, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Dec; 362(6):512-9. PubMed ID: 11138843
    [Abstract] [Full Text] [Related]

  • 11. Equipotent allosteric effect of W84 on [3H]NMS-binding to cardiac muscarinic receptors from guinea-pig, rat, and pig.
    Mohr K, Staschen CM, Ziegenhagen M.
    Pharmacol Toxicol; 1992 Mar; 70(3):198-200. PubMed ID: 1579545
    [Abstract] [Full Text] [Related]

  • 12. Probing the selectivity of allosteric modulators of muscarinic receptors at other G-protein-coupled receptors.
    Pfaffendorf M, Batink HD, Tränkle C, Mohr K, van Zwieten PA.
    J Auton Pharmacol; 2000 Feb; 20(1):55-62. PubMed ID: 11048962
    [Abstract] [Full Text] [Related]

  • 13. Interaction of the hexamethonium derivative W84, an allosteric effector at muscarinic cholinoreceptors, with rat brain nicotinic binding sites.
    Leithäuser F, Mohr K, Staschen CM.
    Pharmacol Toxicol; 1990 Oct; 67(4):317-21. PubMed ID: 2077524
    [Abstract] [Full Text] [Related]

  • 14. A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor.
    Steinfeld T, Mammen M, Smith JA, Wilson RD, Jasper JR.
    Mol Pharmacol; 2007 Aug; 72(2):291-302. PubMed ID: 17478612
    [Abstract] [Full Text] [Related]

  • 15. Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors.
    Voigtländer U, Jöhren K, Mohr M, Raasch A, Tränkle C, Buller S, Ellis J, Höltje HD, Mohr K.
    Mol Pharmacol; 2003 Jul; 64(1):21-31. PubMed ID: 12815157
    [Abstract] [Full Text] [Related]

  • 16. Allosteric modulators and selective agonists of muscarinic receptors.
    Holzgrabe U, De Amici M, Mohr K.
    J Mol Neurosci; 2006 Jul; 30(1-2):165-8. PubMed ID: 17192667
    [Abstract] [Full Text] [Related]

  • 17. Muscarinic allosteric modulation: M2/M3 subtype selectivity of gallamine is independent of G-protein coupling specificity.
    Tränkle C, Kostenis E, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2001 Aug; 364(2):172-8. PubMed ID: 11534857
    [Abstract] [Full Text] [Related]

  • 18. Two populations of muscarinic binding sites in the chick heart distinguished by affinities for ligands and selective inactivation.
    Jakubík J, Tucek S.
    Br J Pharmacol; 1994 Dec; 113(4):1529-37. PubMed ID: 7889311
    [Abstract] [Full Text] [Related]

  • 19. Development of a new type of allosteric modulator of muscarinic receptors: hybrids of the antagonist AF-DX 384 and the hexamethonio derivative W84.
    Mohr M, Heller E, Ataie A, Mohr K, Holzgrabe U.
    J Med Chem; 2004 Jun 03; 47(12):3324-7. PubMed ID: 15163212
    [Abstract] [Full Text] [Related]

  • 20. Allosteric interactions with muscarinic acetylcholine receptors: complex role of the conserved tryptophan M2422Trp in a critical cluster of amino acids for baseline affinity, subtype selectivity, and cooperativity.
    Prilla S, Schrobang J, Ellis J, Höltje HD, Mohr K.
    Mol Pharmacol; 2006 Jul 03; 70(1):181-93. PubMed ID: 16641315
    [Abstract] [Full Text] [Related]

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