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Journal Abstract Search

158 related items for PubMed ID: 9661025

  • 1. Anti-hepatitis B virus activity and metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine.
    Zhu YL, Dutschman DE, Liu SH, Bridges EG, Cheng YC.
    Antimicrob Agents Chemother; 1998 Jul; 42(7):1805-10. PubMed ID: 9661025
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro.
    Dutschman GE, Bridges EG, Liu SH, Gullen E, Guo X, Kukhanova M, Cheng YC.
    Antimicrob Agents Chemother; 1998 Jul; 42(7):1799-804. PubMed ID: 9661024
    [Abstract] [Full Text] [Related]

  • 3. Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues.
    Fu L, Liu SH, Cheng YC.
    Biochem Pharmacol; 1999 Jun 15; 57(12):1351-9. PubMed ID: 10353255
    [Abstract] [Full Text] [Related]

  • 4. Comparative evaluation of L-Fd4C and related nucleoside analogs as promising antiviral agents.
    Chen SH.
    Curr Med Chem; 2002 May 15; 9(9):899-912. PubMed ID: 11966452
    [Abstract] [Full Text] [Related]

  • 5. Characterization of the antiviral effect of 2',3'-dideoxy-2', 3'-didehydro-beta-L-5-fluorocytidine in the duck hepatitis B virus infection model.
    Le Guerhier F, Pichoud C, Guerret S, Chevallier M, Jamard C, Hantz O, Li XY, Chen SH, King I, Trépo C, Cheng YC, Zoulim F.
    Antimicrob Agents Chemother; 2000 Jan 15; 44(1):111-22. PubMed ID: 10602731
    [Abstract] [Full Text] [Related]

  • 6. Biochemical pharmacology of (+)- and (-)-2',3'-dideoxy-3'-thiacytidine as anti-hepatitis B virus agents.
    Chang CN, Skalski V, Zhou JH, Cheng YC.
    J Biol Chem; 1992 Nov 05; 267(31):22414-20. PubMed ID: 1331054
    [Abstract] [Full Text] [Related]

  • 7. Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro.
    Lin TS, Luo MZ, Liu MC, Zhu YL, Gullen E, Dutschman GE, Cheng YC.
    J Med Chem; 1996 Apr 26; 39(9):1757-9. PubMed ID: 8627596
    [No Abstract] [Full Text] [Related]

  • 8. Antiviral activity of beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine in woodchucks chronically infected with woodchuck hepatitis virus.
    Le Guerhier F, Pichoud C, Jamard C, Guerret S, Chevallier M, Peyrol S, Hantz O, King I, Trépo C, Cheng YC, Zoulim F.
    Antimicrob Agents Chemother; 2001 Apr 26; 45(4):1065-77. PubMed ID: 11257017
    [Abstract] [Full Text] [Related]

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  • 11. Synthesis and comparative evaluation of two antiviral agents: beta-L-Fd4C and beta-D-Fd4C.
    Chen SH, Lin S, King I, Spinka T, Dutschman GE, Gullen EA, Cheng YC, Doyle TW.
    Bioorg Med Chem Lett; 1998 Nov 17; 8(22):3245-50. PubMed ID: 9873711
    [Abstract] [Full Text] [Related]

  • 12. Use of the hepatitis B virus recombinant baculovirus-HepG2 system to study the effects of (-)-beta-2',3'-dideoxy-3'-thiacytidine on replication of hepatitis B virus and accumulation of covalently closed circular DNA.
    Delaney WE, Miller TG, Isom HC.
    Antimicrob Agents Chemother; 1999 Aug 17; 43(8):2017-26. PubMed ID: 10428929
    [Abstract] [Full Text] [Related]

  • 13. Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma.
    Hart GJ, Orr DC, Penn CR, Figueiredo HT, Gray NM, Boehme RE, Cameron JM.
    Antimicrob Agents Chemother; 1992 Aug 17; 36(8):1688-94. PubMed ID: 1384425
    [Abstract] [Full Text] [Related]

  • 14. Animal models for the study of HBV infection and the evaluation of new anti-HBV strategies.
    Zoulim F, Berthillon P, Guerhier FL, Seigneres B, Germon S, Pichoud C, Cheng YC, Trepo C.
    J Gastroenterol Hepatol; 2002 Dec 17; 17 Suppl():S460-3. PubMed ID: 12534778
    [Abstract] [Full Text] [Related]

  • 15. Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates.
    Lam W, Li Y, Liou JY, Dutschman GE, Cheng YC.
    Mol Pharmacol; 2004 Feb 17; 65(2):400-6. PubMed ID: 14742682
    [Abstract] [Full Text] [Related]

  • 16. Cellular pharmacology of the anti-hepatitis B virus agent beta-L-2',3'-didehydro-2',3'-dideoxy-N4-hydroxycytidine: relevance for activation in HepG2 cells.
    Matthes E, Bünger H.
    Antimicrob Agents Chemother; 2010 Jan 17; 54(1):341-5. PubMed ID: 19917760
    [Abstract] [Full Text] [Related]

  • 17. Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells.
    Xie H, Voronkov M, Liotta DC, Korba BA, Schinazi RF, Richman DD, Hostetler KY.
    Antiviral Res; 1995 Oct 17; 28(2):113-20. PubMed ID: 8585765
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of 2',3'-dideoxy-L-pyrimidine nucleosides as potential antiviral agents against human immunodeficiency virus (HIV) and hepatitis B virus (HBV).
    Lin TS, Luo MZ, Liu MC, Pai SB, Dutschman GE, Cheng YC.
    J Med Chem; 1994 Mar 18; 37(6):798-803. PubMed ID: 8145230
    [Abstract] [Full Text] [Related]

  • 19. Antiviral activity of 5'-O-carbonate-2',3'-dideoxy-3'-thiacytidine prodrugs against hepatitis B virus in HepG2 2.2.15 cells.
    Gagey D, Ravetti S, Castro EF, Gualdesi MS, Briñon MC, Campos RH, Cavallaro LV.
    Int J Antimicrob Agents; 2010 Dec 18; 36(6):566-9. PubMed ID: 20947311
    [Abstract] [Full Text] [Related]

  • 20. Anti-HIV and anti-HBV activity and resistance profile of 2',3'-dideoxy-3'-thiacytidine (3TC) and its arylphosphoramidate derivative CF 1109.
    Balzarini J, Wedgwood O, Kruining J, Pelemans H, Heijtink R, De Clercq E, McGuigan C.
    Biochem Biophys Res Commun; 1996 Aug 14; 225(2):363-9. PubMed ID: 8753770
    [Abstract] [Full Text] [Related]

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