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Journal Abstract Search

202 related items for PubMed ID: 9666482

  • 21. Alzheimer's disease. Molecular consequences of presenilin-1 mutation.
    Gandy S, Naslund J, Nordstedt C.
    Nature; 2001 Jun 07; 411(6838):654-6. PubMed ID: 11395757
    [Abstract] [Full Text] [Related]

  • 22. Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.
    Ramalho RM, Borralho PM, Castro RE, Solá S, Steer CJ, Rodrigues CM.
    J Neurochem; 2006 Sep 07; 98(5):1610-8. PubMed ID: 16923170
    [Abstract] [Full Text] [Related]

  • 23. Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.
    Saura CA, Tomita T, Davenport F, Harris CL, Iwatsubo T, Thinakaran G.
    J Biol Chem; 1999 May 14; 274(20):13818-23. PubMed ID: 10318786
    [Abstract] [Full Text] [Related]

  • 24. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
    [Abstract] [Full Text] [Related]

  • 25. Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane.
    Kaether C, Lammich S, Edbauer D, Ertl M, Rietdorf J, Capell A, Steiner H, Haass C.
    J Cell Biol; 2002 Aug 05; 158(3):551-61. PubMed ID: 12147673
    [Abstract] [Full Text] [Related]

  • 26. [Beta-amyloid protein: recent progress in basic research and therapeutic approaches].
    Iwatsubo T.
    Rinsho Shinkeigaku; 2001 Dec 05; 41(12):1198-200. PubMed ID: 12235837
    [Abstract] [Full Text] [Related]

  • 27. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
    Jankowsky JL, Slunt HH, Gonzales V, Jenkins NA, Copeland NG, Borchelt DR.
    Neurobiol Aging; 2004 Aug 05; 25(7):885-92. PubMed ID: 15212842
    [Abstract] [Full Text] [Related]

  • 28. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells.
    Palacino JJ, Berechid BE, Alexander P, Eckman C, Younkin S, Nye JS, Wolozin B.
    J Biol Chem; 2000 Jan 07; 275(1):215-22. PubMed ID: 10617607
    [Abstract] [Full Text] [Related]

  • 29. Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production.
    Suga K, Tomiyama T, Mori H, Akagawa K.
    Biochem J; 2004 Aug 01; 381(Pt 3):619-28. PubMed ID: 15109302
    [Abstract] [Full Text] [Related]

  • 30. Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.
    Thinakaran G, Harris CL, Ratovitski T, Davenport F, Slunt HH, Price DL, Borchelt DR, Sisodia SS.
    J Biol Chem; 1997 Nov 07; 272(45):28415-22. PubMed ID: 9353300
    [Abstract] [Full Text] [Related]

  • 31. Unraveling the molecular pathway of Alzheimer's disease: research about presenilins gathers momentum.
    Sandbrink R, Beyreuther K.
    Mol Psychiatry; 1996 Dec 07; 1(6):438-44. PubMed ID: 9154244
    [Abstract] [Full Text] [Related]

  • 32. Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.
    Culvenor JG, Maher F, Evin G, Malchiodi-Albedi F, Cappai R, Underwood JR, Davis JB, Karran EH, Roberts GW, Beyreuther K, Masters CL.
    J Neurosci Res; 1997 Sep 15; 49(6):719-31. PubMed ID: 9335259
    [Abstract] [Full Text] [Related]

  • 33. Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease.
    Xia W, Zhang J, Perez R, Koo EH, Selkoe DJ.
    Proc Natl Acad Sci U S A; 1997 Jul 22; 94(15):8208-13. PubMed ID: 9223340
    [Abstract] [Full Text] [Related]

  • 34. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo.
    Thinakaran G, Borchelt DR, Lee MK, Slunt HH, Spitzer L, Kim G, Ratovitsky T, Davenport F, Nordstedt C, Seeger M, Hardy J, Levey AI, Gandy SE, Jenkins NA, Copeland NG, Price DL, Sisodia SS.
    Neuron; 1996 Jul 22; 17(1):181-90. PubMed ID: 8755489
    [Abstract] [Full Text] [Related]

  • 35. Effects of presenilin N-terminal fragments on production of amyloid beta peptide and accumulation of endogenous presenilins.
    Shirotani K, Takahashi K, Tabira T.
    Neurosci Lett; 1999 Feb 26; 262(1):37-40. PubMed ID: 10076867
    [Abstract] [Full Text] [Related]

  • 36. Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.
    Verdile G, Martins RN, Duthie M, Holmes E, St George-Hyslop PH, Fraser PE.
    J Biol Chem; 2000 Jul 07; 275(27):20794-8. PubMed ID: 10801777
    [Abstract] [Full Text] [Related]

  • 37. The influence of endoproteolytic processing of familial Alzheimer's disease presenilin 2 on abeta42 amyloid peptide formation.
    Jacobsen H, Reinhardt D, Brockhaus M, Bur D, Kocyba C, Kurt H, Grim MG, Baumeister R, Loetscher H.
    J Biol Chem; 1999 Dec 03; 274(49):35233-9. PubMed ID: 10575009
    [Abstract] [Full Text] [Related]

  • 38. Hyperaccumulation of FAD-linked presenilin 1 variants in vivo.
    Lee MK, Borchelt DR, Kim G, Thinakaran G, Slunt HH, Ratovitski T, Martin LJ, Kittur A, Gandy S, Levey AI, Jenkins N, Copeland N, Price DL, Sisodia SS.
    Nat Med; 1997 Jul 03; 3(7):756-60. PubMed ID: 9212102
    [Abstract] [Full Text] [Related]

  • 39. Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins.
    Xia W, Zhang J, Kholodenko D, Citron M, Podlisny MB, Teplow DB, Haass C, Seubert P, Koo EH, Selkoe DJ.
    J Biol Chem; 1997 Mar 21; 272(12):7977-82. PubMed ID: 9065468
    [Abstract] [Full Text] [Related]

  • 40. Metabolism of presenilin 1: influence of presenilin 1 on amyloid precursor protein processing.
    Borchelt DR.
    Neurobiol Aging; 1998 Mar 21; 19(1 Suppl):S15-8. PubMed ID: 9562461
    [Abstract] [Full Text] [Related]

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