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Journal Abstract Search


508 related items for PubMed ID: 9671538

  • 1. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.
    Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL.
    Chem Res Toxicol; 1998 Jul; 11(7):758-65. PubMed ID: 9671538
    [Abstract] [Full Text] [Related]

  • 2. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
    Zhang F, Chen Y, Pisha E, Shen L, Xiong Y, van Breemen RB, Bolton JL.
    Chem Res Toxicol; 1999 Feb; 12(2):204-13. PubMed ID: 10027800
    [Abstract] [Full Text] [Related]

  • 3. Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.
    Yao J, Li Y, Chang M, Wu H, Yang X, Goodman JE, Liu X, Liu H, Mesecar AD, Van Breemen RB, Yager JD, Bolton JL.
    Chem Res Toxicol; 2003 May; 16(5):668-75. PubMed ID: 12755597
    [Abstract] [Full Text] [Related]

  • 4. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.
    Chen Y, Shen L, Zhang F, Lau SS, van Breemen RB, Nikolic D, Bolton JL.
    Chem Res Toxicol; 1998 Sep; 11(9):1105-11. PubMed ID: 9760286
    [Abstract] [Full Text] [Related]

  • 5. Bioactivation of estrone and its catechol metabolites to quinoid-glutathione conjugates in rat liver microsomes.
    Iverson SL, Shen L, Anlar N, Bolton JL.
    Chem Res Toxicol; 1996 Mar; 9(2):492-9. PubMed ID: 8839054
    [Abstract] [Full Text] [Related]

  • 6. Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin.
    Chang M, Shin YG, van Breemen RB, Blond SY, Bolton JL.
    Biochemistry; 2001 Apr 17; 40(15):4811-20. PubMed ID: 11294649
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1.
    Yao J, Chang M, Li Y, Pisha E, Liu X, Yao D, Elguindi EC, Blond SY, Bolton JL.
    Chem Res Toxicol; 2002 Jul 17; 15(7):935-42. PubMed ID: 12119004
    [Abstract] [Full Text] [Related]

  • 8. Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expression.
    Cuendet M, Liu X, Pisha E, Li Y, Yao J, Yu L, Bolton JL.
    Mutat Res; 2004 Jun 04; 550(1-2):109-21. PubMed ID: 15135645
    [Abstract] [Full Text] [Related]

  • 9. Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase.
    Li Y, Yao J, Chang M, Nikolic D, Yu L, Yager JD, Mesecar AD, van Breemen RB, Bolton JL.
    Chem Res Toxicol; 2004 Apr 04; 17(4):512-20. PubMed ID: 15089093
    [Abstract] [Full Text] [Related]

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  • 11. Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.
    Liu X, Zhang F, Liu H, Burdette JE, Li Y, Overk CR, Pisha E, Yao J, van Breemen RB, Swanson SM, Bolton JL.
    Chem Res Toxicol; 2003 Jun 04; 16(6):741-9. PubMed ID: 12807357
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of the equine estrogen metabolites 2-hydroxyequilin and 2-hydroxyequilenin.
    Zhang F, Bolton JL.
    Chem Res Toxicol; 1999 Feb 04; 12(2):200-3. PubMed ID: 10027799
    [Abstract] [Full Text] [Related]

  • 13. Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens.
    Wang Z, Chandrasena ER, Yuan Y, Peng KW, van Breemen RB, Thatcher GR, Bolton JL.
    Chem Res Toxicol; 2010 Aug 16; 23(8):1365-73. PubMed ID: 20509668
    [Abstract] [Full Text] [Related]

  • 14. Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.
    Shen L, Pisha E, Huang Z, Pezzuto JM, Krol E, Alam Z, van Breemen RB, Bolton JL.
    Carcinogenesis; 1997 May 16; 18(5):1093-101. PubMed ID: 9163701
    [Abstract] [Full Text] [Related]

  • 15. A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
    Chen Y, Liu X, Pisha E, Constantinou AI, Hua Y, Shen L, van Breemen RB, Elguindi EC, Blond SY, Zhang F, Bolton JL.
    Chem Res Toxicol; 2000 May 16; 13(5):342-50. PubMed ID: 10813650
    [Abstract] [Full Text] [Related]

  • 16. 17 beta-estradiol metabolism by hamster hepatic microsomes: comparison of catechol estrogen O-methylation with catechol estrogen oxidation and glutathione conjugation.
    Butterworth M, Lau SS, Monks TJ.
    Chem Res Toxicol; 1996 Jun 16; 9(4):793-9. PubMed ID: 8831825
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  • 18. Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin.
    Kolbanovskiy A, Kuzmin V, Shastry A, Kolbanovskaya M, Chen D, Chang M, Bolton JL, Geacintov NE.
    Chem Res Toxicol; 2005 Nov 16; 18(11):1737-47. PubMed ID: 16300383
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and reactivity of the catechol metabolites from the equine estrogen, 8,9-dehydroestrone.
    Zhang F, Yao D, Hua Y, van Breemen RB, Bolton JL.
    Chem Res Toxicol; 2001 Jun 16; 14(6):754-63. PubMed ID: 11409947
    [Abstract] [Full Text] [Related]

  • 20. NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms.
    Zhang N, Ding S, Kolbanovskiy A, Shastry A, Kuzmin VA, Bolton JL, Patel DJ, Broyde S, Geacintov NE.
    Biochemistry; 2009 Aug 04; 48(30):7098-109. PubMed ID: 19527068
    [Abstract] [Full Text] [Related]


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