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202 related items for PubMed ID: 9679543

  • 1. Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.
    Hayes JD, Pulford DJ, Ellis EM, McLeod R, James RF, Seidegård J, Mosialou E, Jernström B, Neal GE.
    Chem Biol Interact; 1998 Apr 24; 111-112():51-67. PubMed ID: 9679543
    [Abstract] [Full Text] [Related]

  • 2. Regulation of glutathione S-transferases and aldehyde reductase by chemoprotectors: studies of mechanisms responsible for inducible resistance to aflatoxin B1.
    Hayes JD, McLeod R, Ellis EM, Pulford DJ, Ireland LS, McLellan LI, Judah DJ, Manson MM, Neal GE.
    IARC Sci Publ; 1996 Apr 24; (139):175-87. PubMed ID: 8923030
    [Abstract] [Full Text] [Related]

  • 3. Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver.
    Kelly VP, Ellis EM, Manson MM, Chanas SA, Moffat GJ, McLeod R, Judah DJ, Neal GE, Hayes JD.
    Cancer Res; 2000 Feb 15; 60(4):957-69. PubMed ID: 10706111
    [Abstract] [Full Text] [Related]

  • 4. Ethoxyquin-induced resistance to aflatoxin B1 in the rat is associated with the expression of a novel alpha-class glutathione S-transferase subunit, Yc2, which possesses high catalytic activity for aflatoxin B1-8,9-epoxide.
    Hayes JD, Judah DJ, McLellan LI, Kerr LA, Peacock SD, Neal GE.
    Biochem J; 1991 Oct 15; 279 ( Pt 2)(Pt 2):385-98. PubMed ID: 1953636
    [Abstract] [Full Text] [Related]

  • 5. Regulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectors.
    McLellan LI, Judah DJ, Neal GE, Hayes JD.
    Biochem J; 1994 May 15; 300 ( Pt 1)(Pt 1):117-24. PubMed ID: 8198522
    [Abstract] [Full Text] [Related]

  • 6. Characterization of the rat glutathione S-transferase Yc2 subunit gene, GSTA5: identification of a putative antioxidant-responsive element in the 5'-flanking region of rat GSTA5 that may mediate chemoprotection against aflatoxin B1.
    Pulford DJ, Hayes JD.
    Biochem J; 1996 Aug 15; 318 ( Pt 1)(Pt 1):75-84. PubMed ID: 8761455
    [Abstract] [Full Text] [Related]

  • 7. Protection conferred by selenium deficiency against aflatoxin B1 in the rat is associated with the hepatic expression of an aldo-keto reductase and a glutathione S-transferase subunit that metabolize the mycotoxin.
    McLeod R, Ellis EM, Arthur JR, Neal GE, Judah DJ, Manson MM, Hayes JD.
    Cancer Res; 1997 Oct 01; 57(19):4257-66. PubMed ID: 9331086
    [Abstract] [Full Text] [Related]

  • 8. Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B(1)-induced preneoplasia.
    Shepherd AG, Manson MM, Ball HW, McLellan LI.
    Carcinogenesis; 2000 Oct 01; 21(10):1827-34. PubMed ID: 11023540
    [Abstract] [Full Text] [Related]

  • 9. Resistance to aflatoxin B1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxic aldehyde-containing metabolite of the toxin.
    Hayes JD, Judah DJ, Neal GE.
    Cancer Res; 1993 Sep 01; 53(17):3887-94. PubMed ID: 8395332
    [Abstract] [Full Text] [Related]

  • 10. An ethoxyquin-inducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldo-keto reductases.
    Ellis EM, Judah DJ, Neal GE, Hayes JD.
    Proc Natl Acad Sci U S A; 1993 Nov 01; 90(21):10350-4. PubMed ID: 8234296
    [Abstract] [Full Text] [Related]

  • 11. Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
    Kensler TW, Egner PA, Davidson NE, Roebuck BD, Pikul A, Groopman JD.
    Cancer Res; 1986 Aug 01; 46(8):3924-31. PubMed ID: 2873884
    [Abstract] [Full Text] [Related]

  • 12. Molecular cloning and heterologous expression of a cDNA encoding a mouse glutathione S-transferase Yc subunit possessing high catalytic activity for aflatoxin B1-8,9-epoxide.
    Hayes JD, Judah DJ, Neal GE, Nguyen T.
    Biochem J; 1992 Jul 01; 285 ( Pt 1)(Pt 1):173-80. PubMed ID: 1637297
    [Abstract] [Full Text] [Related]

  • 13. Modification of aflatoxin B1 binding to DNA in vivo in rats fed phenolic antioxidants, ethoxyquin and a dithiothione.
    Kensler TW, Egner PA, Trush MA, Bueding E, Groopman JD.
    Carcinogenesis; 1985 May 01; 6(5):759-63. PubMed ID: 3924431
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
    Roebuck BD, Curphey TJ, Li Y, Baumgartner KJ, Bodreddigari S, Yan J, Gange SJ, Kensler TW, Sutter TR.
    Carcinogenesis; 2003 Dec 01; 24(12):1919-28. PubMed ID: 14555609
    [Abstract] [Full Text] [Related]

  • 15. Cloning of cDNAs from fetal rat liver encoding glutathione S-transferase Yc polypeptides. The Yc2 subunit is expressed in adult rat liver resistant to the hepatocarcinogen aflatoxin B1.
    Hayes JD, Nguyen T, Judah DJ, Petersson DG, Neal GE.
    J Biol Chem; 1994 Aug 12; 269(32):20707-17. PubMed ID: 8051171
    [Abstract] [Full Text] [Related]

  • 16. Metabolic basis for the protective effect of the antioxidant ethoxyquin on aflatoxin B1 hepatocarcinogenesis in the rat.
    Mandel HG, Manson MM, Judah DJ, Simpson JL, Green JA, Forrester LM, Wolf CR, Neal GE.
    Cancer Res; 1987 Oct 01; 47(19):5218-23. PubMed ID: 2887284
    [Abstract] [Full Text] [Related]

  • 17. Effects of dietary oltipraz and ethoxyquin on aflatoxin B1 biotransformation in non-human primates.
    Bammler TK, Slone DH, Eaton DL.
    Toxicol Sci; 2000 Mar 01; 54(1):30-41. PubMed ID: 10746929
    [Abstract] [Full Text] [Related]

  • 18. Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.
    Buetler TM, Bammler TK, Hayes JD, Eaton DL.
    Cancer Res; 1996 May 15; 56(10):2306-13. PubMed ID: 8625305
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism.
    Manson MM, Ball HW, Barrett MC, Clark HL, Judah DJ, Williamson G, Neal GE.
    Carcinogenesis; 1997 Sep 15; 18(9):1729-38. PubMed ID: 9328168
    [Abstract] [Full Text] [Related]

  • 20. Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors.
    Ellis EM, Judah DJ, Neal GE, O'Connor T, Hayes JD.
    Cancer Res; 1996 Jun 15; 56(12):2758-66. PubMed ID: 8665510
    [Abstract] [Full Text] [Related]

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