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Journal Abstract Search

326 related items for PubMed ID: 9680068

  • 1. Stereoselective synthesis of peptidyl trifluoromethyl alcohols and ketones: inhibitory potency against human leucocyte elastase, cathepsin G, porcine pancreatic elastase and HIV-1 protease.
    Amour A, Reboud-Ravaux M, de Rosny E, Abouabdellah A, Bégue JP, Bonnet-Delpon D, Le Gall M.
    J Pharm Pharmacol; 1998 Jun; 50(6):593-600. PubMed ID: 9680068
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G.
    Peet NP, Burkhart JP, Angelastro MR, Giroux EL, Mehdi S, Bey P, Kolb M, Neises B, Schirlin D.
    J Med Chem; 1990 Jan; 33(1):394-407. PubMed ID: 2296031
    [Abstract] [Full Text] [Related]

  • 3. Non-peptidic inhibitors of human leukocyte elastase. 1. The design and synthesis of pyridone-containing inhibitors.
    Warner P, Green RC, Gomes B, Strimpler AM.
    J Med Chem; 1994 Sep 16; 37(19):3090-9. PubMed ID: 7932532
    [Abstract] [Full Text] [Related]

  • 4. 6-Acylamino-2-1[(ethylsulfonyl)oxy]-1H-isoindole-1,3-diones mechanism-based inhibitors of human leukocyte elastase and cathepsin G: effect of chirality in the 6-acylamino substituent on inhibitory potency and selectivity.
    Vagnoni LM, Gronostaj M, Kerrigan JE.
    Bioorg Med Chem; 2001 Mar 16; 9(3):637-45. PubMed ID: 11310598
    [Abstract] [Full Text] [Related]

  • 5. Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G.
    Zembower DE, Kam CM, Powers JC, Zalkow LH.
    J Med Chem; 1992 May 01; 35(9):1597-605. PubMed ID: 1578486
    [Abstract] [Full Text] [Related]

  • 6. Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters.
    Oleksyszyn J, Powers JC.
    Biochemistry; 1991 Jan 15; 30(2):485-93. PubMed ID: 1988040
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity studies of fluoroketone inhibitors of alpha-lytic protease and human leukocyte elastase.
    Govardhan CP, Abeles RH.
    Arch Biochem Biophys; 1990 Jul 15; 280(1):137-46. PubMed ID: 2353815
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  • 9. The inhibition of human neutrophil elastase and cathepsin G by peptidyl 1,2-dicarbonyl derivatives.
    Mehdi S, Angelastro MR, Burkhart JP, Koehl JR, Peet NP, Bey P.
    Biochem Biophys Res Commun; 1990 Jan 30; 166(2):595-600. PubMed ID: 2302225
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  • 12. Mechanism of slow-binding inhibition of human leukocyte elastase by trifluoromethyl ketones.
    Stein RL, Strimpler AM, Edwards PD, Lewis JJ, Mauger RC, Schwartz JA, Stein MM, Trainor DA, Wildonger RA, Zottola MA.
    Biochemistry; 1987 May 19; 26(10):2682-9. PubMed ID: 3649251
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  • 14. Binding pockets on the surface of human leukocyte elastase and human leukocyte cathepsin G. Implications to the design of inhibitors derived from human C-reactive protein.
    Yavin EJ, Eisenstein M, Fridkin M.
    Biomed Pept Proteins Nucleic Acids; 1987 May 19; 2(3):71-8. PubMed ID: 9575343
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  • 15. Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils.
    Groutas WC, Huang H, Epp JB, Venkataraman R, McClenahan JJ, Tagusagawa F.
    Biochim Biophys Acta; 1994 Nov 29; 1227(3):130-6. PubMed ID: 7986820
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of serine proteases by peptidyl fluoromethyl ketones.
    Imperiali B, Abeles RH.
    Biochemistry; 1986 Jul 01; 25(13):3760-7. PubMed ID: 3527255
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  • 18. The kinetic mechanism of inhibition of human leukocyte elastase by MR889, a new cyclic thiolic compound.
    Baici A, Pelloso R, Hörler D.
    Biochem Pharmacol; 1990 Mar 01; 39(5):919-24. PubMed ID: 2310417
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  • 19. Inhibition of human serine proteases by substituted 2-azetidinones.
    Knight WB, Chabin R, Green B.
    Arch Biochem Biophys; 1992 Aug 01; 296(2):704-8. PubMed ID: 1632655
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  • 20. Nonpeptidic inhibitors of human leukocyte elastase. 5. Design, synthesis, and X-ray crystallography of a series of orally active 5-aminopyrimidin-6-one-containing trifluoromethyl ketones.
    Veale CA, Bernstein PR, Bryant C, Ceccarelli C, Damewood JR, Earley R, Feeney SW, Gomes B, Kosmider BJ, Steelman GB.
    J Med Chem; 1995 Jan 06; 38(1):98-108. PubMed ID: 7837246
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