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217 related items for PubMed ID: 9694919

  • 1. Prevention of thrombosis and enhancement of thrombolysis in rabbits by SR 121787, a glycoprotein II/III antagonist.
    Hoffmann P, Bernat A, Savi P, Herbert JM.
    J Pharmacol Exp Ther; 1998 Aug; 286(2):670-5. PubMed ID: 9694919
    [Abstract] [Full Text] [Related]

  • 2. Antiplatelet and antithrombotic efficacy of SR 121787, a nonpeptide orally active GP IIb/IIIa antagonist, in rabbits: comparison with clopidogrel and aspirin.
    Hoffmann P, Bernat A, Savi P, Herbert JM.
    J Cardiovasc Pharmacol; 1997 Sep; 30(3):360-6. PubMed ID: 9300321
    [Abstract] [Full Text] [Related]

  • 3. SR 121787, a new orally active fibrinogen receptor antagonist.
    Savi P, Badorc A, Lalé A, Bordes MF, Bornia J, Labouret C, Bernat A, de Cointet P, Hoffmann P, Maffrand JP, Herbert JM.
    Thromb Haemost; 1998 Sep; 80(3):469-76. PubMed ID: 9759629
    [Abstract] [Full Text] [Related]

  • 4. Effect of SR121566A, a potent GP IIb-IIIa antagonist on platelet-mediated thrombin generation in vitro and in vivo.
    Herault JP, Peyrou V, Savi P, Bernat A, Herbert JM.
    Thromb Haemost; 1998 Feb; 79(2):383-8. PubMed ID: 9493595
    [Abstract] [Full Text] [Related]

  • 5. New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent.
    Badorc A, Bordes MF, de Cointet P, Savi P, Bernat A, Lalé A, Petitou M, Maffrand JP, Herbert JM.
    J Med Chem; 1997 Oct 10; 40(21):3393-401. PubMed ID: 9341914
    [Abstract] [Full Text] [Related]

  • 6. Antithrombotic activity of SR 46349, a novel, potent and selective 5-HT2 receptor antagonist.
    Herbert JM, Bernat A, Barthelemy G, Dol F, Rinaldi M.
    Thromb Haemost; 1993 Mar 01; 69(3):262-7. PubMed ID: 8470049
    [Abstract] [Full Text] [Related]

  • 7. Nonpeptide glycoprotein IIb/IIIa inhibitors. 15. Antithrombotic efficacy of L-738,167, a long-acting GPIIb/IIIa antagonist, correlates with inhibition of adenosine diphosphate-induced platelet aggregation but not with bleeding time prolongation.
    Cook JJ, Sitko GR, Holahan MA, Stranieri MT, Glass JD, Askew BC, McIntyre CJ, Claremon DA, Baldwin JJ, Hartman GD, Gould RJ, Lynch JJ.
    J Pharmacol Exp Ther; 1997 May 01; 281(2):677-89. PubMed ID: 9152373
    [Abstract] [Full Text] [Related]

  • 8. Effect of aspirin on platelet desaggregation induced by SR121566, a potent GP-IIb/IIIa antagonist.
    Savi P, Bernat A, Lalé A, Roque C, Zamboni G, Herbert JM.
    Platelets; 2000 Feb 01; 11(1):43-8. PubMed ID: 10938881
    [Abstract] [Full Text] [Related]

  • 9. ME3277, a GPIIb/IIIa antagonist reduces cerebral infarction without enhancing intracranial hemorrhage in photothrombotic occlusion of rabbit middle cerebral artery.
    Kawano KI, Fujishima K, Ikeda Y, Kondo K, Umemura K.
    J Cereb Blood Flow Metab; 2000 Jun 01; 20(6):988-97. PubMed ID: 10894182
    [Abstract] [Full Text] [Related]

  • 10. Interspecies comparison of the antiplatelet, antithrombotic, and hemorrhagic effects of SR 121566A, a novel nonpeptide GP IIb/IIIa antagonist.
    Bernat A, Hoffmann P, Savi P, Lalé A, Herbert JM.
    J Cardiovasc Pharmacol; 1999 Jun 01; 33(6):897-904. PubMed ID: 10367593
    [Abstract] [Full Text] [Related]

  • 11. Antiplatelet and antithrombotic effects of YM337, the Fab fragment of a humanized anti-GPIIb/IIIa monoclonal antibody in monkeys.
    Kaku S, Kawasaki T, Hisamichi N, Sakai Y, Taniuchi Y, Inagaki O, Yano S, Suzuki K, Terazaki C, Masuho Y, Satoh N, Takenaka T, Yanagi K, Ohshima N.
    Thromb Haemost; 1996 Apr 01; 75(4):679-84. PubMed ID: 8743199
    [Abstract] [Full Text] [Related]

  • 12. Nonpeptide glycoprotein IIb/IIIa inhibitors: 14: oral antithrombotic efficacy of L-738,167 in a conscious canine model of coronary artery electrolytic injury.
    Cook JJ, Glass JD, Sitko GR, Holahan MA, Stupienski RF, Wallace AA, Stump GL, Hand EL, Askew BC, Hartman GD, Gould RJ, Lynch JJ.
    Circulation; 1997 Aug 05; 96(3):949-58. PubMed ID: 9264506
    [Abstract] [Full Text] [Related]

  • 13. The antiaggregating and antithrombotic activity of clopidogrel is potentiated by aspirin in several experimental models in the rabbit.
    Herbert JM, Dol F, Bernat A, Falotico R, Lalé A, Savi P.
    Thromb Haemost; 1998 Sep 05; 80(3):512-8. PubMed ID: 9759636
    [Abstract] [Full Text] [Related]

  • 14. Antithrombotic effects of MK-0852, a platelet fibrinogen receptor antagonist, in canine models of thrombosis.
    Ramjit DR, Lynch JJ, Sitko GR, Mellott MJ, Holahan MA, Stabilito II, Stranieri MT, Zhang G, Lynch RJ, Manno PD.
    J Pharmacol Exp Ther; 1993 Sep 05; 266(3):1501-11. PubMed ID: 8371153
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of microsurgical thrombosis by the platelet glycoprotein IIb/IIIa antagonist SR121566A.
    Ching S, Thoma A, Monkman S, Kelton JG.
    Plast Reconstr Surg; 2003 Jul 05; 112(1):177-85. PubMed ID: 12832891
    [Abstract] [Full Text] [Related]

  • 16. The antithrombotic efficacy of the GP IIb/IIIa antagonist SR121787 is potentiated by antithrombin-dependent factor Xa inhibition without an increase in the bleeding risk in the rabbit.
    Bernat A, Savi P, Lale A, Hoffmann P, Herbert JM.
    J Cardiovasc Pharmacol; 1999 Apr 05; 33(4):573-9. PubMed ID: 10218727
    [Abstract] [Full Text] [Related]

  • 17. Antagonism of the GPIIb/IIIa receptor with the nonpeptidic molecule BIBU52: inhibition of platelet aggregation in vitro and antithrombotic efficacy in vivo.
    Guth BD, Seewaldt-Becker E, Himmelsbach F, Weisenberger H, Müller TH.
    J Cardiovasc Pharmacol; 1997 Aug 05; 30(2):261-72. PubMed ID: 9269956
    [Abstract] [Full Text] [Related]

  • 18. Antiplatelet effect of FK633, a platelet glycoprotein IIb/IIIa antagonist, on thrombus formation and vascular patency after thrombolysis in the injured hamster carotid artery.
    Kaida T, Matsuno H, Niwa M, Kozawa O, Miyata H, Uematsu T.
    Thromb Haemost; 1997 Mar 05; 77(3):562-7. PubMed ID: 9066011
    [Abstract] [Full Text] [Related]

  • 19. Restoration of middle cerebral artery thrombosis by novel glycoprotein IIb/IIIa antagonist FK419 in guinea pig.
    Moriguchi A, Mihara K, Aoki T, Maeda M, Tojo N, Matsuoka N, Mutoh S.
    Eur J Pharmacol; 2004 Sep 13; 498(1-3):179-88. PubMed ID: 15363993
    [Abstract] [Full Text] [Related]

  • 20. Nonpeptide factor Xa inhibitors III: effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits.
    Wong PC, Crain EJ, Watson CA, Zaspel AM, Wright MR, Lam PY, Pinto DJ, Wexler RR, Knabb RM.
    J Pharmacol Exp Ther; 2002 Dec 13; 303(3):993-1000. PubMed ID: 12438519
    [Abstract] [Full Text] [Related]

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