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347 related items for PubMed ID: 9699643

  • 1. Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library.
    Zhu Z, Rockwell P, Lu D, Kotanides H, Pytowski B, Hicklin DJ, Bohlen P, Witte L.
    Cancer Res; 1998 Aug 01; 58(15):3209-14. PubMed ID: 9699643
    [Abstract] [Full Text] [Related]

  • 2. Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor.
    Lu D, Jimenez X, Zhang H, Wu Y, Bohlen P, Witte L, Zhu Z.
    Cancer Res; 2001 Oct 01; 61(19):7002-8. PubMed ID: 11585724
    [Abstract] [Full Text] [Related]

  • 3. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.
    Wood JM, Bold G, Buchdunger E, Cozens R, Ferrari S, Frei J, Hofmann F, Mestan J, Mett H, O'Reilly T, Persohn E, Rösel J, Schnell C, Stover D, Theuer A, Towbin H, Wenger F, Woods-Cook K, Menrad A, Siemeister G, Schirner M, Thierauch KH, Schneider MR, Drevs J, Martiny-Baron G, Totzke F.
    Cancer Res; 2000 Apr 15; 60(8):2178-89. PubMed ID: 10786682
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody.
    Zhu Z, Lu D, Kotanides H, Santiago A, Jimenez X, Simcox T, Hicklin DJ, Bohlen P, Witte L.
    Cancer Lett; 1999 Mar 01; 136(2):203-13. PubMed ID: 10355750
    [Abstract] [Full Text] [Related]

  • 5. Anti-VEGFR-2 scFvs for cell isolation. Single-chain antibodies recognizing the human vascular endothelial growth factor receptor-2 (VEGFR-2/flk-1) on the surface of primary endothelial cells and preselected CD34+ cells from cord blood.
    Böldicke T, Tesar M, Griesel C, Rohde M, Gröne HJ, Waltenberger J, Kollet O, Lapidot T, Yayon A, Weich H.
    Stem Cells; 2001 Mar 01; 19(1):24-36. PubMed ID: 11209088
    [Abstract] [Full Text] [Related]

  • 6. Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor.
    Pan B, Li B, Russell SJ, Tom JY, Cochran AG, Fairbrother WJ.
    J Mol Biol; 2002 Feb 22; 316(3):769-87. PubMed ID: 11866530
    [Abstract] [Full Text] [Related]

  • 7. The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts.
    Takahashi T, Shibuya M.
    Oncogene; 1997 May 01; 14(17):2079-89. PubMed ID: 9160888
    [Abstract] [Full Text] [Related]

  • 8. A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.
    Takahashi T, Yamaguchi S, Chida K, Shibuya M.
    EMBO J; 2001 Jun 01; 20(11):2768-78. PubMed ID: 11387210
    [Abstract] [Full Text] [Related]

  • 9. Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice.
    Brekken RA, Overholser JP, Stastny VA, Waltenberger J, Minna JD, Thorpe PE.
    Cancer Res; 2000 Sep 15; 60(18):5117-24. PubMed ID: 11016638
    [Abstract] [Full Text] [Related]

  • 10. A strategy for antitumor vascular therapy by targeting the vascular endothelial growth factor: receptor complex.
    Cooke SP, Boxer GM, Lawrence L, Pedley RB, Spencer DI, Begent RH, Chester KA.
    Cancer Res; 2001 May 01; 61(9):3653-9. PubMed ID: 11325835
    [Abstract] [Full Text] [Related]

  • 11. Role of VEGF receptor-1 (Flt-1) in mediating calcium-dependent nitric oxide release and limiting DNA synthesis in human trophoblast cells.
    Ahmed A, Dunk C, Kniss D, Wilkes M.
    Lab Invest; 1997 Jun 01; 76(6):779-91. PubMed ID: 9194854
    [Abstract] [Full Text] [Related]

  • 12. Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation.
    Yano S, Herbst RS, Shinohara H, Knighton B, Bucana CD, Killion JJ, Wood J, Fidler IJ.
    Clin Cancer Res; 2000 Mar 01; 6(3):957-65. PubMed ID: 10741721
    [Abstract] [Full Text] [Related]

  • 13. Developmental expression of vascular endothelial growth factor (VEGF) receptors and VEGF binding in ovine placenta and fetal membranes.
    Bogic LV, Brace RA, Cheung CY.
    Placenta; 2001 Apr 01; 22(4):265-75. PubMed ID: 11286562
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of vascular endothelial growth factor (VEGF) as a novel approach for cancer therapy.
    Wood JM.
    Medicina (B Aires); 2000 Apr 01; 60 Suppl 2():41-7. PubMed ID: 11188930
    [Abstract] [Full Text] [Related]

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  • 16. Up-regulation of flk-1/vascular endothelial growth factor receptor 2 by its ligand in a cerebral slice culture system.
    Kremer C, Breier G, Risau W, Plate KH.
    Cancer Res; 1997 Sep 01; 57(17):3852-9. PubMed ID: 9288799
    [Abstract] [Full Text] [Related]

  • 17. The coronary endothelium: a target for vascular endothelial growth factor. Human coronary artery endothelial cells express functional receptors for vascular endothelial growth factor in vitro and in vivo.
    Kranz A, Mayr U, Frank H, Waltenberger J.
    Lab Invest; 1999 Aug 01; 79(8):985-91. PubMed ID: 10462036
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  • 20. Induction of KDR expression in bovine arterial endothelial cells by thrombin: involvement of nitric oxide.
    Wang J, Morita I, Onodera M, Murota SI.
    J Cell Physiol; 2002 Feb 01; 190(2):238-50. PubMed ID: 11807828
    [Abstract] [Full Text] [Related]


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