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Journal Abstract Search

254 related items for PubMed ID: 9700656

  • 1.
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  • 2. [Presenilins as a marker of Alzheimer's disease].
    Scheper W, van Gool WA.
    Ned Tijdschr Geneeskd; 1998 May 30; 142(22):1247-52. PubMed ID: 9749296
    [Abstract] [Full Text] [Related]

  • 3. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC, Hudson M, Kanning KC, Schecterson LC, Bothwell M.
    J Neurochem; 2005 Sep 30; 94(5):1189-201. PubMed ID: 15992373
    [Abstract] [Full Text] [Related]

  • 4. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
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  • 6. Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
    Podlisny MB, Citron M, Amarante P, Sherrington R, Xia W, Zhang J, Diehl T, Levesque G, Fraser P, Haass C, Koo EH, Seubert P, St George-Hyslop P, Teplow DB, Selkoe DJ.
    Neurobiol Dis; 1997 Nov 24; 3(4):325-37. PubMed ID: 9173929
    [Abstract] [Full Text] [Related]

  • 7. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES, Martinez M, Brunkan AL, Goate A.
    J Neurochem; 2005 Jan 24; 92(2):294-301. PubMed ID: 15663477
    [Abstract] [Full Text] [Related]

  • 8. Mean age of onset in familial Alzheimer's disease is determined by amyloid beta 42.
    Duering M, Grimm MO, Grimm HS, Schröder J, Hartmann T.
    Neurobiol Aging; 2005 Jun 24; 26(6):785-8. PubMed ID: 15718035
    [Abstract] [Full Text] [Related]

  • 9. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
    Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ.
    Nature; 1999 Apr 08; 398(6727):513-7. PubMed ID: 10206644
    [Abstract] [Full Text] [Related]

  • 10. Alzheimer's disease-associated presenilins 1 and 2: accelerated amyloid fibril formation of mutant 410 Cys-->Tyr and 141 Asn-->Ile peptides.
    Maury CP, Nurmiaho-Lassila EL, Liljeström M.
    Biochem Biophys Res Commun; 1997 Jun 09; 235(1):249-52. PubMed ID: 9196071
    [Abstract] [Full Text] [Related]

  • 11. [Genetic factors in the pathogenesis of Alzheimer's disease: roles of beta-amyloid and presenilins].
    Iwatsubo T, Tomita T.
    Tanpakushitsu Kakusan Koso; 1998 Oct 09; 43(13):1963-72. PubMed ID: 9789459
    [No Abstract] [Full Text] [Related]

  • 12. Unraveling the molecular pathway of Alzheimer's disease: research about presenilins gathers momentum.
    Sandbrink R, Beyreuther K.
    Mol Psychiatry; 1996 Dec 09; 1(6):438-44. PubMed ID: 9154244
    [Abstract] [Full Text] [Related]

  • 13. Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.
    Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Sommer B, van de Wetering M, Clevers H, Saftig P, De Strooper B, He X, Yankner BA.
    Nature; 1998 Oct 15; 395(6703):698-702. PubMed ID: 9790190
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  • 14.
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  • 15. Generation of amyloid beta protein from a presenilin-1 and betaAPP complex.
    Shizuka-Ikeda M, Matsubara E, Ikeda M, Kanai M, Tomidokoro Y, Ikeda Y, Watanabe M, Kawarabayashi T, Harigaya Y, Okamoto K, Maruyama K, Castaño EM, St George-Hyslop P, Shoji M.
    Biochem Biophys Res Commun; 2002 Mar 29; 292(2):571-8. PubMed ID: 11906199
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  • 18. Presenilin mutations in Alzheimer's disease.
    Cruts M, Van Broeckhoven C.
    Hum Mutat; 1998 Mar 29; 11(3):183-90. PubMed ID: 9521418
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  • 19.
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  • 20. New presenilin 1 mutation with Alzheimer disease and Lewy bodies.
    Rosenberg RN.
    Arch Neurol; 2005 Dec 29; 62(12):1808. PubMed ID: 16344337
    [No Abstract] [Full Text] [Related]

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