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Journal Abstract Search


275 related items for PubMed ID: 9701246

  • 1. A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet.
    Powell-Braxton L, Véniant M, Latvala RD, Hirano KI, Won WB, Ross J, Dybdal N, Zlot CH, Young SG, Davidson NO.
    Nat Med; 1998 Aug; 4(8):934-8. PubMed ID: 9701246
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  • 2. Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a).
    Sanan DA, Newland DL, Tao R, Marcovina S, Wang J, Mooser V, Hammer RE, Hobbs HH.
    Proc Natl Acad Sci U S A; 1998 Apr 14; 95(8):4544-9. PubMed ID: 9539774
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  • 3. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.
    Purcell-Huynh DA, Farese RV, Johnson DF, Flynn LM, Pierotti V, Newland DL, Linton MF, Sanan DA, Young SG.
    J Clin Invest; 1995 May 14; 95(5):2246-57. PubMed ID: 7738190
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  • 4. LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis: Insight From Mouse Models.
    Cedó L, Metso J, Santos D, García-León A, Plana N, Sabate-Soler S, Rotllan N, Rivas-Urbina A, Méndez-Lara KA, Tondo M, Girona J, Julve J, Pallarès V, Benitez-Amaro A, Llorente-Cortes V, Pérez A, Gómez-Coronado D, Ruotsalainen AK, Levonen AL, Sanchez-Quesada JL, Masana L, Kovanen PT, Jauhiainen M, Lee-Rueckert M, Blanco-Vaca F, Escolà-Gil JC.
    Circ Res; 2020 Aug 28; 127(6):778-792. PubMed ID: 32495699
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  • 5. Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR+/- and LDLR-/-) Yucatan Miniature Pigs.
    Burke AC, Telford DE, Sutherland BG, Edwards JY, Sawyez CG, Barrett PHR, Newton RS, Pickering JG, Huff MW.
    Arterioscler Thromb Vasc Biol; 2018 May 28; 38(5):1178-1190. PubMed ID: 29449335
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  • 6. Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100.
    Véniant MM, Sullivan MA, Kim SK, Ambroziak P, Chu A, Wilson MD, Hellerstein MK, Rudel LL, Walzem RL, Young SG.
    J Clin Invest; 2000 Dec 28; 106(12):1501-10. PubMed ID: 11120757
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  • 7. The peroxisome proliferator-activated receptor alpha (PPARalpha) agonist ciprofibrate inhibits apolipoprotein B mRNA editing in low density lipoprotein receptor-deficient mice: effects on plasma lipoproteins and the development of atherosclerotic lesions.
    Fu T, Mukhopadhyay D, Davidson NO, Borensztajn J.
    J Biol Chem; 2004 Jul 02; 279(27):28662-9. PubMed ID: 15123680
    [Abstract] [Full Text] [Related]

  • 8. Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia.
    Kassim SH, Li H, Bell P, Somanathan S, Lagor W, Jacobs F, Billheimer J, Wilson JM, Rader DJ.
    Hum Gene Ther; 2013 Jan 02; 24(1):19-26. PubMed ID: 22985273
    [Abstract] [Full Text] [Related]

  • 9. Constitutive androstane receptor activation decreases plasma apolipoprotein B-containing lipoproteins and atherosclerosis in low-density lipoprotein receptor-deficient mice.
    Sberna AL, Assem M, Xiao R, Ayers S, Gautier T, Guiu B, Deckert V, Chevriaux A, Grober J, Le Guern N, Pais de Barros JP, Moore DD, Lagrost L, Masson D.
    Arterioscler Thromb Vasc Biol; 2011 Oct 02; 31(10):2232-9. PubMed ID: 21778422
    [Abstract] [Full Text] [Related]

  • 10. Relationships of plasma and hepatic variables with rates of plasma low-density lipoprotein apolipoprotein B metabolism in baboons fed low- and high-fat diets.
    Kushwaha RS, Barrett PH, Reardon CA, Lewis DS, Carey KD, Getz GS, McGill HC.
    Metabolism; 1995 Aug 02; 44(8):1058-66. PubMed ID: 7637648
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  • 12. LCAT modulates atherogenic plasma lipoproteins and the extent of atherosclerosis only in the presence of normal LDL receptors in transgenic rabbits.
    Brousseau ME, Kauffman RD, Herderick EE, Demosky SJ, Evans W, Marcovina S, Santamarina-Fojo S, Brewer HB, Hoeg JM.
    Arterioscler Thromb Vasc Biol; 2000 Feb 02; 20(2):450-8. PubMed ID: 10669643
    [Abstract] [Full Text] [Related]

  • 13. Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice.
    Persson L, Borén J, Robertson AK, Wallenius V, Hansson GK, Pekna M.
    Arterioscler Thromb Vasc Biol; 2004 Jun 02; 24(6):1062-7. PubMed ID: 15059809
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  • 18. Phenotype interaction of apobec-1 and CETP, LDLR, and apoE gene expression in mice: role of apoB mRNA editing in lipoprotein phenotype expression.
    Nakamuta M, Taniguchi S, Ishida BY, Kobayashi K, Chan L.
    Arterioscler Thromb Vasc Biol; 1998 May 02; 18(5):747-55. PubMed ID: 9598833
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  • 20. Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes.
    Goldberg IJ, Hu Y, Noh HL, Wei J, Huggins LA, Rackmill MG, Hamai H, Reid BN, Blaner WS, Huang LS.
    Diabetes; 2008 Jun 02; 57(6):1674-82. PubMed ID: 18346984
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