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Journal Abstract Search

179 related items for PubMed ID: 9701251

  • 1. Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.
    Guo Q, Fu W, Xie J, Luo H, Sells SF, Geddes JW, Bondada V, Rangnekar VM, Mattson MP.
    Nat Med; 1998 Aug; 4(8):957-62. PubMed ID: 9701251
    [Abstract] [Full Text] [Related]

  • 2. Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice.
    Xie J, Chang X, Zhang X, Guo Q.
    Brain Res; 2001 Oct 05; 915(1):1-10. PubMed ID: 11578614
    [Abstract] [Full Text] [Related]

  • 3. AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4.
    Guo Q, Xie J.
    J Biol Chem; 2004 Feb 06; 279(6):4596-603. PubMed ID: 14627703
    [Abstract] [Full Text] [Related]

  • 4. Prostate apoptosis response-4 enhances secretion of amyloid beta peptide 1-42 in human neuroblastoma IMR-32 cells by a caspase-dependent pathway.
    Guo Q, Xie J, Chang X, Du H.
    J Biol Chem; 2001 May 11; 276(19):16040-4. PubMed ID: 11278808
    [Abstract] [Full Text] [Related]

  • 5. Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease.
    Ohyagi Y, Asahara H, Chui DH, Tsuruta Y, Sakae N, Miyoshi K, Yamada T, Kikuchi H, Taniwaki T, Murai H, Ikezoe K, Furuya H, Kawarabayashi T, Shoji M, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira J, Tabira T.
    FASEB J; 2005 Feb 11; 19(2):255-7. PubMed ID: 15548589
    [Abstract] [Full Text] [Related]

  • 6. Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration.
    Duan W, Rangnekar VM, Mattson MP.
    J Neurochem; 1999 Jun 11; 72(6):2312-22. PubMed ID: 10349840
    [Abstract] [Full Text] [Related]

  • 7. A suicide note from Alzheimer disease neurons?
    Perry G, Nunomura A, Smith MA.
    Nat Med; 1998 Aug 11; 4(8):897-8. PubMed ID: 9701239
    [No Abstract] [Full Text] [Related]

  • 8. Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w.
    Yao M, Nguyen TV, Pike CJ.
    J Neurosci; 2005 Feb 02; 25(5):1149-58. PubMed ID: 15689551
    [Abstract] [Full Text] [Related]

  • 9. Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death.
    Su JH, Anderson AJ, Cribbs DH, Tu C, Tong L, Kesslack P, Cotman CW.
    Neurobiol Dis; 2003 Apr 02; 12(3):182-93. PubMed ID: 12742739
    [Abstract] [Full Text] [Related]

  • 10. Par-4 induces cholinergic hypoactivity by suppressing ChAT protein synthesis and inhibiting NGF-inducibility of ChAT activity.
    Guo Q, Xie J, Du H.
    Brain Res; 2000 Aug 25; 874(2):221-32. PubMed ID: 10960608
    [Abstract] [Full Text] [Related]

  • 11. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.
    Guo Q, Sopher BL, Furukawa K, Pham DG, Robinson N, Martin GM, Mattson MP.
    J Neurosci; 1997 Jun 01; 17(11):4212-22. PubMed ID: 9151738
    [Abstract] [Full Text] [Related]

  • 12. Is apoptosis key in Alzheimer's disease?
    Barinaga M.
    Science; 1998 Aug 28; 281(5381):1303-4. PubMed ID: 9735049
    [No Abstract] [Full Text] [Related]

  • 13. Prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation.
    Chan SL, Tammariello SP, Estus S, Mattson MP.
    J Neurochem; 1999 Aug 28; 73(2):502-12. PubMed ID: 10428045
    [Abstract] [Full Text] [Related]

  • 14. Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations.
    Guo Q, Fu W, Holtsberg FW, Steiner SM, Mattson MP.
    J Neurosci Res; 1999 Jun 01; 56(5):457-70. PubMed ID: 10369213
    [Abstract] [Full Text] [Related]

  • 15. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation.
    Wolozin B, Iwasaki K, Vito P, Ganjei JK, Lacanà E, Sunderland T, Zhao B, Kusiak JW, Wasco W, D'Adamio L.
    Science; 1996 Dec 06; 274(5293):1710-3. PubMed ID: 8939861
    [Abstract] [Full Text] [Related]

  • 16. Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1.
    Mattson MP, Robinson N, Guo Q.
    Neuroreport; 1997 Dec 01; 8(17):3817-21. PubMed ID: 9427376
    [Abstract] [Full Text] [Related]

  • 17. Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.
    Biswas SC, Shi Y, Vonsattel JP, Leung CL, Troy CM, Greene LA.
    J Neurosci; 2007 Jan 24; 27(4):893-900. PubMed ID: 17251431
    [Abstract] [Full Text] [Related]

  • 18. Participation of prostate apoptosis response-4 in degeneration of dopaminergic neurons in models of Parkinson's disease.
    Duan W, Zhang Z, Gash DM, Mattson MP.
    Ann Neurol; 1999 Oct 24; 46(4):587-97. PubMed ID: 10514095
    [Abstract] [Full Text] [Related]

  • 19. The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis.
    Zhu H, Fu W, Mattson MP.
    J Neurochem; 2000 Jul 24; 75(1):117-24. PubMed ID: 10854254
    [Abstract] [Full Text] [Related]

  • 20. The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure.
    Mairuae N, Hall Ii EC, Cheepsunthorn P, Lee SY, Connor JR.
    J Neurosci Res; 2010 Nov 01; 88(14):3079-89. PubMed ID: 20734416
    [Abstract] [Full Text] [Related]

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