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176 related items for PubMed ID: 9703866

  • 1. Treatment of human glioblastoma cells with the staurosporine derivative CGP 41251 inhibits CDC2 and CDK2 kinase activity and increases radiation sensitivity.
    Begemann M, Kashimawo SA, Heitjan DF, Schiff PB, Bruce JN, Weinstein IB.
    Anticancer Res; 1998; 18(4A):2275-82. PubMed ID: 9703866
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of the growth of glioblastomas by CGP 41251, an inhibitor of protein kinase C, and by a phorbol ester tumor promoter.
    Begemann M, Kashimawo SA, Choi YA, Kim S, Christiansen KM, Duigou G, Mueller M, Schieren I, Ghosh S, Fabbro D, Lampen NM, Heitjan DF, Schiff PB, Bruce JN, Weinstein IB.
    Clin Cancer Res; 1996 Jun; 2(6):1017-30. PubMed ID: 9816263
    [Abstract] [Full Text] [Related]

  • 3. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB, Guo B, Panadero A, Frank C, Wrzosek C, Slocum HK, Rustum YM.
    Exp Cell Res; 1999 Feb 25; 247(1):189-99. PubMed ID: 10047461
    [Abstract] [Full Text] [Related]

  • 4. Differential effects of UCN-01, staurosporine and CGP 41 251 on cell cycle progression and CDC2/cyclin B1 regulation in A431 cells synchronized at M phase by nocodazole.
    Akiyama T, Shimizu M, Okabe M, Tamaoki T, Akinaga S.
    Anticancer Drugs; 1999 Jan 25; 10(1):67-78. PubMed ID: 10194549
    [Abstract] [Full Text] [Related]

  • 5. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T, Yoshida T, Tsujita T, Shimizu M, Mizukami T, Okabe M, Akinaga S.
    Cancer Res; 1997 Apr 15; 57(8):1495-501. PubMed ID: 9108451
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL, Buffolino P, Kopman C, Nathanson L.
    Exp Cell Res; 1995 Nov 15; 221(1):92-102. PubMed ID: 7589260
    [Abstract] [Full Text] [Related]

  • 7. Growth inhibition induced by Ro 31-8220 and calphostin C in human glioblastoma cell lines is associated with apoptosis and inhibition of CDC2 kinase.
    Begemann M, Kashimawo SA, Lunn RM, Delohery T, Choi YJ, Kim S, Heitjan DF, Santella RM, Schiff PB, Bruce JN, Weinstein IB.
    Anticancer Res; 1998 Nov 15; 18(5A):3139-52. PubMed ID: 9858877
    [Abstract] [Full Text] [Related]

  • 8. Bimodal effects of 1R,2R-diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV) on cell cycle checkpoints.
    Kuang J, He G, Huang Z, Khokhar AR, Siddik ZH.
    Clin Cancer Res; 2001 Nov 15; 7(11):3629-39. PubMed ID: 11705886
    [Abstract] [Full Text] [Related]

  • 9. Differential regulation of the synthesis and activity of the major cyclin-dependent kinases, p34cdc2, p33cdk2, and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes.
    Lucas JJ, Szepesi A, Domenico J, Tordai A, Terada N, Gelfand EW.
    J Cell Physiol; 1995 Nov 15; 165(2):406-16. PubMed ID: 7593219
    [Abstract] [Full Text] [Related]

  • 10. Apoptosis in 7-hydroxystaurosporine-treated T lymphoblasts correlates with activation of cyclin-dependent kinases 1 and 2.
    Wang Q, Worland PJ, Clark JL, Carlson BA, Sausville EA.
    Cell Growth Differ; 1995 Aug 15; 6(8):927-36. PubMed ID: 8547221
    [Abstract] [Full Text] [Related]

  • 11. Expression and subcellular localization of CDK2 and cdc2 kinases and their common partner cyclin A in thyroid epithelial cells: comparison of cyclic AMP-dependent and -independent cell cycles.
    Baptist M, Lamy F, Gannon J, Hunt T, Dumont JE, Roger PP.
    J Cell Physiol; 1996 Feb 15; 166(2):256-73. PubMed ID: 8591985
    [Abstract] [Full Text] [Related]

  • 12. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
    Patel V, Lahusen T, Leethanakul C, Igishi T, Kremer M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS, Senderowicz AM.
    Clin Cancer Res; 2002 Nov 15; 8(11):3549-60. PubMed ID: 12429646
    [Abstract] [Full Text] [Related]

  • 13. G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.
    O'Connor PM, Ferris DK, Pagano M, Draetta G, Pines J, Hunter T, Longo DL, Kohn KW.
    J Biol Chem; 1993 Apr 15; 268(11):8298-308. PubMed ID: 8463339
    [Abstract] [Full Text] [Related]

  • 14. Different mechanisms for inhibition of cell proliferation via cell cycle proteins in PC12 cells by nerve growth factor and staurosporine.
    Gollapudi L, Neet KE.
    J Neurosci Res; 1997 Aug 15; 49(4):461-74. PubMed ID: 9285522
    [Abstract] [Full Text] [Related]

  • 15. Both low and high concentrations of staurosporine induce G1 arrest through down-regulation of cyclin E and cdk2 expression.
    Zong ZP, Fujikawa-Yamamoto K, Li AL, Yamaguchi N, Chang YG, Murakami M, Odashima S, Ishikawa Y.
    Cell Struct Funct; 1999 Dec 15; 24(6):457-63. PubMed ID: 10698260
    [Abstract] [Full Text] [Related]

  • 16. S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells.
    Hu B, Mitra J, van den Heuvel S, Enders GH.
    Mol Cell Biol; 2001 Apr 15; 21(8):2755-66. PubMed ID: 11283255
    [Abstract] [Full Text] [Related]

  • 17. Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27Kip1 into cyclin E/CDK2 complexes.
    Cheney IW, Neuteboom ST, Vaillancourt MT, Ramachandra M, Bookstein R.
    Cancer Res; 1999 May 15; 59(10):2318-23. PubMed ID: 10344736
    [Abstract] [Full Text] [Related]

  • 18. Interferon-alpha delays S-phase progression in human hepatocellular carcinoma cells via inhibition of specific cyclin-dependent kinases.
    Murphy D, Detjen KM, Welzel M, Wiedenmann B, Rosewicz S.
    Hepatology; 2001 Feb 15; 33(2):346-56. PubMed ID: 11172336
    [Abstract] [Full Text] [Related]

  • 19. Characterization of the in vitro reconstituted cyclin A or B1-dependent cdk2 and cdc2 kinase activities.
    Pan ZQ, Amin A, Hurwitz J.
    J Biol Chem; 1993 Sep 25; 268(27):20443-51. PubMed ID: 8397207
    [Abstract] [Full Text] [Related]

  • 20. Induced G2/M arrest and apoptosis in human epidermoid carcinoma cell lines by semisynthetic drug Ukrain.
    Roublevskaia IN, Polevoda BV, Ludlow JW, Haake AR.
    Anticancer Res; 2000 Sep 25; 20(5A):3163-7. PubMed ID: 11062738
    [Abstract] [Full Text] [Related]

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