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152 related items for PubMed ID: 9705220
21. The effect of the Glu342Lys mutation in alpha1-antitrypsin on its structure, studied by molecular modelling methods. Jezierski G, Pasenkiewicz-Gierula M. Acta Biochim Pol; 2001; 48(1):65-75. PubMed ID: 11440184 [Abstract] [Full Text] [Related]
22. A kinetic mechanism for the polymerization of alpha1-antitrypsin. Dafforn TR, Mahadeva R, Elliott PR, Sivasothy P, Lomas DA. J Biol Chem; 1999 Apr 02; 274(14):9548-55. PubMed ID: 10092640 [Abstract] [Full Text] [Related]
23. A 2.6 A structure of a serpin polymer and implications for conformational disease. Huntington JA, Pannu NS, Hazes B, Read RJ, Lomas DA, Carrell RW. J Mol Biol; 1999 Oct 29; 293(3):449-55. PubMed ID: 10543942 [Abstract] [Full Text] [Related]
24. Determining serpin conformational distributions with single molecule fluorescence. Mushero N, Gershenson A. Methods Enzymol; 2011 Oct 29; 501():351-77. PubMed ID: 22078542 [Abstract] [Full Text] [Related]
25. A 2.1 A resolution structure of an uncleaved alpha(1)-antitrypsin shows variability of the reactive center and other loops. Kim S, Woo J, Seo EJ, Yu M, Ryu S. J Mol Biol; 2001 Feb 09; 306(1):109-19. PubMed ID: 11178897 [Abstract] [Full Text] [Related]
26. A novel mode of polymerization of alpha1-proteinase inhibitor. Marszal E, Danino D, Shrake A. J Biol Chem; 2003 May 30; 278(22):19611-8. PubMed ID: 12649292 [Abstract] [Full Text] [Related]
27. Characterization and suppression of dysfunctional human alpha1-antitrypsin variants. Kim MJ, Jung CH, Im H. Biochem Biophys Res Commun; 2006 Apr 28; 343(1):295-302. PubMed ID: 16540089 [Abstract] [Full Text] [Related]
28. alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization. Lomas DA, Elliott PR, Sidhar SK, Foreman RC, Finch JT, Cox DW, Whisstock JC, Carrell RW. J Biol Chem; 1995 Jul 14; 270(28):16864-70. PubMed ID: 7622502 [Abstract] [Full Text] [Related]
29. Loop-sheet polymerization: the mechanism of alpha1-antitrypsin deficiency. Lomas DA. Respir Med; 2000 Aug 14; 94 Suppl C():S3-6. PubMed ID: 10954247 [Abstract] [Full Text] [Related]
30. Dimers initiate and propagate serine protease inhibitor polymerisation. Zhou A, Carrell RW. J Mol Biol; 2008 Jan 04; 375(1):36-42. PubMed ID: 18005992 [Abstract] [Full Text] [Related]
31. Molecular Mechanism of Z α1-Antitrypsin Deficiency. Huang X, Zheng Y, Zhang F, Wei Z, Wang Y, Carrell RW, Read RJ, Chen GQ, Zhou A. J Biol Chem; 2016 Jul 22; 291(30):15674-86. PubMed ID: 27246852 [Abstract] [Full Text] [Related]
32. Effect of the Z mutation on the physical and inhibitory properties of alpha 1-antitrypsin. Lomas DA, Evans DL, Stone SR, Chang WS, Carrell RW. Biochemistry; 1993 Jan 19; 32(2):500-8. PubMed ID: 8422359 [Abstract] [Full Text] [Related]
33. Loop-sheet polymerization: the structural basis of Z alpha 1-antitrypsin accumulation in the liver. Lomas DA. Clin Sci (Lond); 1994 May 19; 86(5):489-95. PubMed ID: 8033502 [Abstract] [Full Text] [Related]
35. Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy. Lomas DA, Mahadeva R. J Clin Invest; 2002 Dec 25; 110(11):1585-90. PubMed ID: 12464660 [No Abstract] [Full Text] [Related]
36. Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; evidence for structure in the urea unfolded state. Tew DJ, Bottomley SP. J Mol Biol; 2001 Nov 09; 313(5):1161-9. PubMed ID: 11700071 [Abstract] [Full Text] [Related]
37. Polymers of alpha(1)-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema. Parmar JS, Mahadeva R, Reed BJ, Farahi N, Cadwallader KA, Keogan MT, Bilton D, Chilvers ER, Lomas DA. Am J Respir Cell Mol Biol; 2002 Jun 09; 26(6):723-30. PubMed ID: 12034572 [Abstract] [Full Text] [Related]
38. Probing the unfolding pathway of alpha1-antitrypsin. James EL, Whisstock JC, Gore MG, Bottomley SP. J Biol Chem; 1999 Apr 02; 274(14):9482-8. PubMed ID: 10092631 [Abstract] [Full Text] [Related]
39. An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1 -antitrypsin upon ligand binding. Nyon MP, Prentice T, Day J, Kirkpatrick J, Sivalingam GN, Levy G, Haq I, Irving JA, Lomas DA, Christodoulou J, Gooptu B, Thalassinos K. Protein Sci; 2015 Aug 02; 24(8):1301-12. PubMed ID: 26011795 [Abstract] [Full Text] [Related]