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Journal Abstract Search

99 related items for PubMed ID: 9713979

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  • 3. Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats.
    Geary RS, Watanabe TA, Truong L, Freier S, Lesnik EA, Sioufi NB, Sasmor H, Manoharan M, Levin AA.
    J Pharmacol Exp Ther; 2001 Mar; 296(3):890-7. PubMed ID: 11181921
    [Abstract] [Full Text] [Related]

  • 4. Pharmacokinetics of phosphorothioate antisense oligodeoxynucleotides.
    Geary RS, Yu RZ, Levin AA.
    Curr Opin Investig Drugs; 2001 Apr; 2(4):562-73. PubMed ID: 11566019
    [Abstract] [Full Text] [Related]

  • 5. Pharmacokinetics and blood-brain barrier transport of [3H]-biotinylated phosphorothioate oligodeoxynucleotide conjugated to a vector-mediated drug delivery system.
    Wu D, Boado RJ, Pardridge WM.
    J Pharmacol Exp Ther; 1996 Jan; 276(1):206-11. PubMed ID: 8558431
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  • 6. Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats.
    Cossum PA, Sasmor H, Dellinger D, Truong L, Cummins L, Owens SR, Markham PM, Shea JP, Crooke S.
    J Pharmacol Exp Ther; 1993 Dec; 267(3):1181-90. PubMed ID: 8166890
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  • 9. Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding.
    Liu X, Smith BJ, Chen C, Callegari E, Becker SL, Chen X, Cianfrogna J, Doran AC, Doran SD, Gibbs JP, Hosea N, Liu J, Nelson FR, Szewc MA, Van Deusen J.
    J Pharmacol Exp Ther; 2005 Jun; 313(3):1254-62. PubMed ID: 15743928
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  • 10. Absolute bioavailability of 2'-O-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats.
    Geary RS, Khatsenko O, Bunker K, Crooke R, Moore M, Burckin T, Truong L, Sasmor H, Levin AA.
    J Pharmacol Exp Ther; 2001 Mar; 296(3):898-904. PubMed ID: 11181922
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  • 12. Biodistribution of 68Ga-labelled phosphodiester, phosphorothioate, and 2'-O-methyl phosphodiester oligonucleotides in normal rats.
    Lendvai G, Velikyan I, Bergström M, Estrada S, Laryea D, Välilä M, Salomäki S, Långström B, Roivainen A.
    Eur J Pharm Sci; 2005 Sep; 26(1):26-38. PubMed ID: 15941654
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  • 14. Pharmacokinetic properties of several novel oligonucleotide analogs in mice.
    Crooke ST, Graham MJ, Zuckerman JE, Brooks D, Conklin BS, Cummins LL, Greig MJ, Guinosso CJ, Kornbrust D, Manoharan M, Sasmor HM, Schleich T, Tivel KL, Griffey RH.
    J Pharmacol Exp Ther; 1996 May; 277(2):923-37. PubMed ID: 8627575
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  • 16. Pharmacokinetics of oligonucleotides.
    Agrawal S, Zhang R.
    Ciba Found Symp; 1997 May; 209():60-75; discussion 75-8. PubMed ID: 9383569
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  • 18. Pharmacokinetics of a 14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats.
    Cossum PA, Truong L, Owens SR, Markham PM, Shea JP, Crooke ST.
    J Pharmacol Exp Ther; 1994 Apr; 269(1):89-94. PubMed ID: 8169856
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  • 20. Pharmacokinetics of antisense oligonucleotides.
    Agrawal S, Temsamani J, Galbraith W, Tang J.
    Clin Pharmacokinet; 1995 Jan; 28(1):7-16. PubMed ID: 7712663
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