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104 related items for PubMed ID: 9720969

  • 1. Generation of reactive oxygen species accounts for cytotoxicity of an endogenous dopaminergic neurotoxin, (R)-N-methylsalsolinol, to differentiated dopaminergic SH-SY5Y cells.
    Minami C, Deng Y, Maruyama W, Takahashi T, Kawai M, Nakahara D, Naoi M.
    J Neural Transm (Vienna); 1998; 105(4-5):397-405. PubMed ID: 9720969
    [Abstract] [Full Text] [Related]

  • 2. An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells.
    Maruyama W, Naoi M, Kasamatsu T, Hashizume Y, Takahashi T, Kohda K, Dostert P.
    J Neurochem; 1997 Jul; 69(1):322-9. PubMed ID: 9202326
    [Abstract] [Full Text] [Related]

  • 3. Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines.
    Naoi M, Maruyama W, Kasamatsu T, Dostert P.
    J Neural Transm Suppl; 1998 Jul; 52():125-38. PubMed ID: 9564615
    [Abstract] [Full Text] [Related]

  • 4. Cytotoxicity of endogenous isoquinolines to human dopaminergic neuroblastoma SH-SY5Y cells.
    Takahashi T, Maruyama W, Deng Y, Dostert P, Nakahara D, Niwa T, Ohta S, Naoi M.
    J Neural Transm (Vienna); 1997 Jul; 104(1):59-66. PubMed ID: 9085193
    [Abstract] [Full Text] [Related]

  • 5. Involvement of endogenous N-methyl(R)salsolinol in Parkinson's disease: induction of apoptosis and protection by (-)deprenyl.
    Naoi M, Maruyama W, Takahashi T, Akao Y, Nakagawa Y.
    J Neural Transm Suppl; 2000 Jul; (58):111-21. PubMed ID: 11128601
    [Abstract] [Full Text] [Related]

  • 6. A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain.
    Maruyama W, Sobue G, Matsubara K, Hashizume Y, Dostert P, Naoi M.
    Neurosci Lett; 1997 Feb 14; 223(1):61-4. PubMed ID: 9058423
    [Abstract] [Full Text] [Related]

  • 7. Enantio-specific induction of apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopaminergic SH-SY5Y cells: suppression of apoptosis by N-(2-heptyl)-N-methylpropargylamine.
    Maruyama W, Boulton AA, Davis BA, Dostert P, Naoi M.
    J Neural Transm (Vienna); 2001 Feb 14; 108(1):11-24. PubMed ID: 11261742
    [Abstract] [Full Text] [Related]

  • 8. Salsolinol, a dopamine-derived tetrahydroisoquinoline, induces cell death by causing oxidative stress in dopaminergic SH-SY5Y cells, and the said effect is attenuated by metallothionein.
    Wanpen S, Govitrapong P, Shavali S, Sangchot P, Ebadi M.
    Brain Res; 2004 Apr 16; 1005(1-2):67-76. PubMed ID: 15044066
    [Abstract] [Full Text] [Related]

  • 9. Cell death of dopamine neurons in aging and Parkinson's disease.
    Naoi M, Maruyama W.
    Mech Ageing Dev; 1999 Nov 16; 111(2-3):175-88. PubMed ID: 10656535
    [Abstract] [Full Text] [Related]

  • 10. A dopaminergic neurotoxin, (R)-N-methylsalsolinol, increases in Parkinsonian cerebrospinal fluid.
    Maruyama W, Abe T, Tohgi H, Dostert P, Naoi M.
    Ann Neurol; 1996 Jul 16; 40(1):119-22. PubMed ID: 8687181
    [Abstract] [Full Text] [Related]

  • 11. Iron contributes to the formation of catechol isoquinolines and oxidative toxicity induced by overdose dopamine in dopaminergic SH-SY5Y cells.
    Wang R, Qing H, Liu XQ, Zheng XL, Deng YL.
    Neurosci Bull; 2008 Jun 16; 24(3):125-32. PubMed ID: 18500384
    [Abstract] [Full Text] [Related]

  • 12. R(-)-deprenyl potentiates dopamine-induced cytotoxicity toward catecholaminergic neuroblastoma SH-SY5Y cells.
    Lai CT, Yu PH.
    Toxicol Appl Pharmacol; 1997 Jan 16; 142(1):186-91. PubMed ID: 9007048
    [Abstract] [Full Text] [Related]

  • 13. Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopamine neurons.
    Naoi M, Maruyama W, Akao Y, Zhang J, Parvez H.
    Toxicology; 2000 Nov 16; 153(1-3):123-41. PubMed ID: 11090952
    [Abstract] [Full Text] [Related]

  • 14. N-methyl(R)salsolinol produces hydroxyl radicals: involvement to neurotoxicity.
    Maruyama W, Dostert P, Matsubara K, Naoi M.
    Free Radic Biol Med; 1995 Jul 16; 19(1):67-75. PubMed ID: 7635360
    [Abstract] [Full Text] [Related]

  • 15. N-methyl-(R)salsolinol as a dopaminergic neurotoxin: from an animal model to an early marker of Parkinson's disease.
    Naoi M, Maruyama W, Dostert P, Hashizume Y.
    J Neural Transm Suppl; 1997 Jul 16; 50():89-105. PubMed ID: 9120428
    [Abstract] [Full Text] [Related]

  • 16. Neuroprotective function of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane, [R-(-)-BPAP], against apoptosis induced by N-methyl(R)salsolinol, an endogenous dopaminergic neurotoxin, in human dopaminergic neuroblastoma SH-SY5Y cells.
    Maruyama W, Yi H, Takahashi T, Shimazu S, Ohde H, Yoneda F, Iwasa K, Naoi M.
    Life Sci; 2004 May 21; 75(1):107-17. PubMed ID: 15102525
    [Abstract] [Full Text] [Related]

  • 17. Anti-apoptotic function of L-(-)deprenyl (Selegiline) and related compounds.
    Naoi M, Maruyama W, Yagi K, Youdim M.
    Neurobiology (Bp); 2000 May 21; 8(1):69-80. PubMed ID: 11008879
    [Abstract] [Full Text] [Related]

  • 18. Type A monoamine oxidase is the target of an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol, leading to apoptosis in SH-SY5Y cells.
    Yi H, Akao Y, Maruyama W, Chen K, Shih J, Naoi M.
    J Neurochem; 2006 Jan 21; 96(2):541-9. PubMed ID: 16336631
    [Abstract] [Full Text] [Related]

  • 19. Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system.
    Takahashi T, Deng Y, Maruyama W, Dostert P, Kawai M, Naoi M.
    J Neural Transm Gen Sect; 1994 Jan 21; 98(2):107-18. PubMed ID: 7734108
    [Abstract] [Full Text] [Related]

  • 20. Dopamine-derived 1-methyl-6,7-dihydroxyisoquinolines as hydroxyl radical promoters and scavengers in the rat brain: in vivo and in vitro studies.
    Maruyama W, Dostert P, Naoi M.
    J Neurochem; 1995 Jun 21; 64(6):2635-43. PubMed ID: 7760044
    [Abstract] [Full Text] [Related]

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