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303 related items for PubMed ID: 9722545
1. Inhibition of membrane lipid-independent protein kinase Calpha activity by phorbol esters, diacylglycerols, and bryostatin-1. Slater SJ, Taddeo FJ, Mazurek A, Stagliano BA, Milano SK, Kelly MB, Ho C, Stubbs CD. J Biol Chem; 1998 Sep 04; 273(36):23160-8. PubMed ID: 9722545 [Abstract] [Full Text] [Related]
2. Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities. Slater SJ, Ho C, Kelly MB, Larkin JD, Taddeo FJ, Yeager MD, Stubbs CD. J Biol Chem; 1996 Mar 01; 271(9):4627-31. PubMed ID: 8617724 [Abstract] [Full Text] [Related]
3. Synergistic activation of protein kinase Calpha, -betaI, and -gamma isoforms induced by diacylglycerol and phorbol ester: roles of membrane association and activating conformational changes. Slater SJ, Milano SK, Stagliano BA, Gergich KJ, Ho C, Mazurek A, Taddeo FJ, Kelly MB, Yeager MD, Stubbs CD. Biochemistry; 1999 Mar 23; 38(12):3804-15. PubMed ID: 10090770 [Abstract] [Full Text] [Related]
6. Conformation of the C1 phorbol-ester-binding domain participates in the activating conformational change of protein kinase C. Ho C, Slater SJ, Stagliano BA, Stubbs CD. Biochem J; 1999 Dec 01; 344 Pt 2(Pt 2):451-60. PubMed ID: 10567228 [Abstract] [Full Text] [Related]
7. Three activators of protein kinase C, bryostatins, dioleins, and phorbol esters, show differing specificities of action on GH4 pituitary cells. Ramsdell JS, Pettit GR, Tashjian AH. J Biol Chem; 1986 Dec 25; 261(36):17073-80. PubMed ID: 3465727 [Abstract] [Full Text] [Related]
10. Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation. Szallasi Z, Denning MF, Smith CB, Dlugosz AA, Yuspa SH, Pettit GR, Blumberg PM. Mol Pharmacol; 1994 Nov 25; 46(5):840-50. PubMed ID: 7969070 [Abstract] [Full Text] [Related]
11. Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines. Kennedy MJ, Prestigiacomo LJ, Tyler G, May WS, Davidson NE. Cancer Res; 1992 Mar 01; 52(5):1278-83. PubMed ID: 1737390 [Abstract] [Full Text] [Related]
12. Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains. Ananthanarayanan B, Stahelin RV, Digman MA, Cho W. J Biol Chem; 2003 Nov 21; 278(47):46886-94. PubMed ID: 12954613 [Abstract] [Full Text] [Related]
13. Interplay of C1 and C2 domains of protein kinase C-alpha in its membrane binding and activation. Medkova M, Cho W. J Biol Chem; 1999 Jul 09; 274(28):19852-61. PubMed ID: 10391930 [Abstract] [Full Text] [Related]
14. Bryostatin 1 induces prolonged activation of extracellular regulated protein kinases in and apoptosis of LNCaP human prostate cancer cells overexpressing protein kinase calpha. Gschwend JE, Fair WR, Powell CT. Mol Pharmacol; 2000 Jun 09; 57(6):1224-34. PubMed ID: 10825394 [Abstract] [Full Text] [Related]
15. Evidence for discrete diacylglycerol and phorbol ester activator sites on protein kinase C. Differences in effects of 1-alkanol inhibition, activation by phosphatidylethanolamine and calcium chelation. Slater SJ, Kelly MB, Taddeo FJ, Rubin E, Stubbs CD. J Biol Chem; 1994 Jun 24; 269(25):17160-5. PubMed ID: 8006023 [Abstract] [Full Text] [Related]
16. The role of protein kinase C isoenzymes in the growth inhibition caused by bryostatin 1 in human A549 lung and MCF-7 breast carcinoma cells. Stanwell C, Gescher A, Bradshaw TD, Pettit GR. Int J Cancer; 1994 Feb 15; 56(4):585-92. PubMed ID: 8112895 [Abstract] [Full Text] [Related]
17. The transient increase of tight junction permeability induced by bryostatin 1 correlates with rapid downregulation of protein kinase C-alpha. Clarke H, Ginanni N, Laughlin KV, Smith JB, Pettit GR, Mullin JM. Exp Cell Res; 2000 Nov 25; 261(1):239-49. PubMed ID: 11082294 [Abstract] [Full Text] [Related]
18. Selective activation by bryostatin-1 demonstrates unique roles for PKC epsilon in neurite extension and tau phosphorylation. Ekinci FJ, Shea TB. Int J Dev Neurosci; 1997 Nov 25; 15(7):867-74. PubMed ID: 9568534 [Abstract] [Full Text] [Related]
19. Tumor promotion by depleting cells of protein kinase C delta. Lu Z, Hornia A, Jiang YW, Zang Q, Ohno S, Foster DA. Mol Cell Biol; 1997 Jun 25; 17(6):3418-28. PubMed ID: 9154841 [Abstract] [Full Text] [Related]
20. Response of Jurkat T cells to phorbol ester and bryostatin. Development of sublines with distinct functional responses and changes in protein kinase C activity. Levine BL, May WS, Tyler PG, Hess AD. J Immunol; 1991 Nov 15; 147(10):3474-81. PubMed ID: 1834742 [Abstract] [Full Text] [Related] Page: [Next] [New Search]