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144 related items for PubMed ID: 9743261

  • 1. Characterization of the transport of a cationic octapeptide, octreotide, in rat bile canalicular membrane: possible involvement of P-glycoprotein.
    Yamada T, Kato Y, Kusuhara H, Lemaire M, Sugiyama Y.
    Biol Pharm Bull; 1998 Aug; 21(8):874-8. PubMed ID: 9743261
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of the tissue distribution and biliary excretion of the cyclic peptide octreotide.
    Yamada T, Niinuma K, Lemaire M, Terasaki T, Sugiyama Y.
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1357-64. PubMed ID: 8968360
    [Abstract] [Full Text] [Related]

  • 3. Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide.
    Niinuma K, Takenaka O, Horie T, Kobayashi K, Kato Y, Suzuki H, Sugiyama Y.
    J Pharmacol Exp Ther; 1997 Aug; 282(2):866-72. PubMed ID: 9262353
    [Abstract] [Full Text] [Related]

  • 4. Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter.
    Yamazaki M, Akiyama S, Ni'inuma K, Nishigaki R, Sugiyama Y.
    Drug Metab Dispos; 1997 Oct; 25(10):1123-9. PubMed ID: 9321514
    [Abstract] [Full Text] [Related]

  • 5. Carrier-mediated hepatic uptake of the cationic cyclopeptide, octreotide, in rats. Comparison between in vivo and in vitro.
    Yamada T, Niinuma K, Lemaire M, Terasaki T, Sugiyama Y.
    Drug Metab Dispos; 1997 May; 25(5):536-43. PubMed ID: 9152591
    [Abstract] [Full Text] [Related]

  • 6. Effects of colchicine and phenothiazine on biliary excretion of organic anions in rats.
    Takikawa H, Sano N, Akimoto K, Ogasawara T, Yamanaka M.
    J Gastroenterol Hepatol; 1998 Apr; 13(4):427-32. PubMed ID: 9641309
    [Abstract] [Full Text] [Related]

  • 7. Induction of hepatic P-glycoprotein enhances biliary excretion of vincristine in rats.
    Watanabe T, Suzuki H, Sawada Y, Naito M, Tsuruo T, Inaba M, Hanano M, Sugiyama Y.
    J Hepatol; 1995 Oct; 23(4):440-8. PubMed ID: 8655962
    [Abstract] [Full Text] [Related]

  • 8. Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats.
    Sasabe H, Tsuji A, Sugiyama Y.
    J Pharmacol Exp Ther; 1998 Mar; 284(3):1033-9. PubMed ID: 9495864
    [Abstract] [Full Text] [Related]

  • 9. Biliary excretion of 17beta-estradiol 17beta-D-glucuronide is predominantly mediated by cMOAT/MRP2.
    Morikawa A, Goto Y, Suzuki H, Hirohashi T, Sugiyama Y.
    Pharm Res; 2000 May; 17(5):546-52. PubMed ID: 10888306
    [Abstract] [Full Text] [Related]

  • 10. Primary active transport of peptidic endothelin antagonists by rat hepatic canalicular membrane.
    Akhteruzzaman S, Kato Y, Hisaka A, Sugiyama Y.
    J Pharmacol Exp Ther; 1999 Feb; 288(2):575-81. PubMed ID: 9918561
    [Abstract] [Full Text] [Related]

  • 11. Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats.
    Masuda M, I'izuka Y, Yamazaki M, Nishigaki R, Kato Y, Ni'inuma K, Suzuki H, Sugiyama Y.
    Cancer Res; 1997 Aug 15; 57(16):3506-10. PubMed ID: 9270020
    [Abstract] [Full Text] [Related]

  • 12. Primary active transport of organic anions on bile canalicular membrane in humans.
    Niinuma K, Kato Y, Suzuki H, Tyson CA, Weizer V, Dabbs JE, Froehlich R, Green CE, Sugiyama Y.
    Am J Physiol; 1999 May 15; 276(5):G1153-64. PubMed ID: 10330006
    [Abstract] [Full Text] [Related]

  • 13. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.
    Paulusma CC, van Geer MA, Evers R, Heijn M, Ottenhoff R, Borst P, Oude Elferink RP.
    Biochem J; 1999 Mar 01; 338 ( Pt 2)(Pt 2):393-401. PubMed ID: 10024515
    [Abstract] [Full Text] [Related]

  • 14. Kinetic analysis of hepatobiliary transport of vincristine in perfused rat liver. Possible roles of P-glycoprotein in biliary excretion of vincristine.
    Watanabe T, Miyauchi S, Sawada Y, Iga T, Hanano M, Inaba M, Sugiyama Y.
    J Hepatol; 1992 Sep 01; 16(1-2):77-88. PubMed ID: 1362433
    [Abstract] [Full Text] [Related]

  • 15. Multispecific organic anion transporter is responsible for the biliary excretion of the camptothecin derivative irinotecan and its metabolites in rats.
    Chu XY, Kato Y, Niinuma K, Sudo KI, Hakusui H, Sugiyama Y.
    J Pharmacol Exp Ther; 1997 Apr 01; 281(1):304-14. PubMed ID: 9103511
    [Abstract] [Full Text] [Related]

  • 16. Multiplicity of biliary excretion mechanisms for the camptothecin derivative irinotecan (CPT-11), its metabolite SN-38, and its glucuronide: role of canalicular multispecific organic anion transporter and P-glycoprotein.
    Sugiyama Y, Kato Y, Chu X.
    Cancer Chemother Pharmacol; 1998 Apr 01; 42 Suppl():S44-9. PubMed ID: 9750028
    [Abstract] [Full Text] [Related]

  • 17. Species differences in the transport activity for organic anions across the bile canalicular membrane.
    Ishizuka H, Konno K, Shiina T, Naganuma H, Nishimura K, Ito K, Suzuki H, Sugiyama Y.
    J Pharmacol Exp Ther; 1999 Sep 01; 290(3):1324-30. PubMed ID: 10454510
    [Abstract] [Full Text] [Related]

  • 18. Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).
    Ishizuka H, Konno K, Naganuma H, Sasahara K, Kawahara Y, Niinuma K, Suzuki H, Sugiyama Y.
    J Pharmacol Exp Ther; 1997 Mar 01; 280(3):1304-11. PubMed ID: 9067317
    [Abstract] [Full Text] [Related]

  • 19. Possible involvement of P-glycoprotein in biliary excretion of CPT-11 in rats.
    Chu XY, Kato Y, Sugiyama Y.
    Drug Metab Dispos; 1999 Apr 01; 27(4):440-1. PubMed ID: 10101137
    [Abstract] [Full Text] [Related]

  • 20. Effects of organic anions and bile acid conjugates on biliary excretion of LTC4 in the rat.
    Kitaura K, Takikawa H, Yamanaka M.
    Prostaglandins; 1997 Nov 01; 54(5):745-55. PubMed ID: 9491205
    [Abstract] [Full Text] [Related]

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