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242 related items for PubMed ID: 9745924

  • 1. Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism.
    Furlong CE, Li WF, Costa LG, Richter RJ, Shih DM, Lusis AJ.
    Neurotoxicology; 1998; 19(4-5):645-50. PubMed ID: 9745924
    [Abstract] [Full Text] [Related]

  • 2. Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1).
    Furlong CE, Li WF, Richter RJ, Shih DM, Lusis AJ, Alleva E, Costa LG.
    Neurotoxicology; 2000; 21(1-2):91-100. PubMed ID: 10794389
    [Abstract] [Full Text] [Related]

  • 3. The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin.
    Davies HG, Richter RJ, Keifer M, Broomfield CA, Sowalla J, Furlong CE.
    Nat Genet; 1996 Nov; 14(3):334-6. PubMed ID: 8896566
    [Abstract] [Full Text] [Related]

  • 4. The PON1 gene and detoxication.
    Furlong CE, Li WF, Brophy VH, Jarvik GP, Richter RJ, Shih DM, Lusis AJ, Costa LG.
    Neurotoxicology; 2000 Aug; 21(4):581-7. PubMed ID: 11022865
    [Abstract] [Full Text] [Related]

  • 5. The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism.
    Costa LG, Li WF, Richter RJ, Shih DM, Lusis A, Furlong CE.
    Chem Biol Interact; 1999 May 14; 119-120():429-38. PubMed ID: 10421480
    [Abstract] [Full Text] [Related]

  • 6. Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds.
    Li WF, Costa LG, Richter RJ, Hagen T, Shih DM, Tward A, Lusis AJ, Furlong CE.
    Pharmacogenetics; 2000 Dec 14; 10(9):767-79. PubMed ID: 11191881
    [Abstract] [Full Text] [Related]

  • 7. The Relationship between PON1 phenotype and PON1-192 genotype in detoxification of three oxons by human liver.
    Mutch E, Daly AK, Williams FM.
    Drug Metab Dispos; 2007 Feb 14; 35(2):315-20. PubMed ID: 17132760
    [Abstract] [Full Text] [Related]

  • 8. Determination of paraoxonase (PON1) status requires more than genotyping.
    Richter RJ, Furlong CE.
    Pharmacogenetics; 1999 Dec 14; 9(6):745-53. PubMed ID: 10634137
    [Abstract] [Full Text] [Related]

  • 9. Serum paraoxonase status: a major factor in determining resistance to organophosphates.
    Li WF, Costa LG, Furlong CE.
    J Toxicol Environ Health; 1993 Dec 14; 40(2-3):337-46. PubMed ID: 7693961
    [Abstract] [Full Text] [Related]

  • 10. Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis.
    Shih DM, Gu L, Xia YR, Navab M, Li WF, Hama S, Castellani LW, Furlong CE, Costa LG, Fogelman AM, Lusis AJ.
    Nature; 1998 Jul 16; 394(6690):284-7. PubMed ID: 9685159
    [Abstract] [Full Text] [Related]

  • 11. Repeated gestational exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1) modulated effects in maternal and fetal tissues.
    Cole TB, Li WF, Co AL, Hay AM, MacDonald JW, Bammler TK, Farin FM, Costa LG, Furlong CE.
    Toxicol Sci; 2014 Oct 16; 141(2):409-22. PubMed ID: 25070982
    [Abstract] [Full Text] [Related]

  • 12. Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity.
    Costa LG, Richter RJ, Li WF, Cole T, Guizzetti M, Furlong CE.
    Biomarkers; 2003 Oct 16; 8(1):1-12. PubMed ID: 12519632
    [Abstract] [Full Text] [Related]

  • 13. Gene-environmental interactions and organophosphate toxicity.
    Povey AC.
    Toxicology; 2010 Dec 30; 278(3):294-304. PubMed ID: 20156521
    [Abstract] [Full Text] [Related]

  • 14. Effect of the molecular polymorphisms of human paraoxonase (PON1) on the rate of hydrolysis of paraoxon.
    Mackness B, Mackness MI, Arrol S, Turkie W, Durrington PN.
    Br J Pharmacol; 1997 Sep 30; 122(2):265-8. PubMed ID: 9313934
    [Abstract] [Full Text] [Related]

  • 15. Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds.
    Furlong CE.
    J Biochem Mol Toxicol; 2007 Sep 30; 21(4):197-205. PubMed ID: 17936934
    [Abstract] [Full Text] [Related]

  • 16. Gene therapy to prevent organophosphate intoxication.
    Cowan J, Sinton CM, Varley AW, Wians FH, Haley RW, Munford RS.
    Toxicol Appl Pharmacol; 2001 May 15; 173(1):1-6. PubMed ID: 11350209
    [Abstract] [Full Text] [Related]

  • 17. Structural organization of the human PON1 gene.
    Clendenning JB, Humbert R, Green ED, Wood C, Traver D, Furlong CE.
    Genomics; 1996 Aug 01; 35(3):586-9. PubMed ID: 8812495
    [Abstract] [Full Text] [Related]

  • 18. Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants.
    Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG.
    Neurotoxicology; 2005 Aug 01; 26(4):651-9. PubMed ID: 16112327
    [Abstract] [Full Text] [Related]

  • 19. Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism.
    Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE.
    Pharmacogenet Genomics; 2005 Aug 01; 15(8):589-98. PubMed ID: 16007003
    [Abstract] [Full Text] [Related]

  • 20. Gastrointestinal nematode infection increases organophosphate toxicity in rats.
    Farid AS, Horii Y.
    Toxicol Lett; 2008 Jul 30; 180(1):33-7. PubMed ID: 18577432
    [Abstract] [Full Text] [Related]

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