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161 related items for PubMed ID: 9748634
1. Characterization of plasminogen activator inhibitor 1 mutants containing the P13 to P10 region of ovalbumin or antithrombin III: evidence that the P13 residue contributes significantly to the active to substrate transition. Gils A, Vleugels N, Tobback K, Knockaert I, Declerck PJ. Biochim Biophys Acta; 1998 Sep 08; 1387(1-2):291-7. PubMed ID: 9748634 [Abstract] [Full Text] [Related]
2. Proteinase specificity and functional diversity in point mutants of plasminogen activator inhibitor 1. Gils A, Declerck PJ. J Biol Chem; 1997 May 09; 272(19):12662-6. PubMed ID: 9139722 [Abstract] [Full Text] [Related]
3. Conversion of plasminogen activator inhibitor-1 from inhibitor to substrate by point mutations in the reactive-site loop. Audenaert AM, Knockaert I, Collen D, Declerck PJ. J Biol Chem; 1994 Jul 29; 269(30):19559-64. PubMed ID: 8034724 [Abstract] [Full Text] [Related]
4. Substrate behavior of plasminogen activator inhibitor-1 is not associated with a lack of insertion of the reactive site loop. Gils A, Knockaert I, Declerck PJ. Biochemistry; 1996 Jun 11; 35(23):7474-81. PubMed ID: 8652525 [Abstract] [Full Text] [Related]
5. Identification of positively charged residues contributing to the stability of plasminogen activator inhibitor 1. Gils A, Lu J, Aertgeerts K, Knockaert I, Declerck PJ. FEBS Lett; 1997 Sep 29; 415(2):192-5. PubMed ID: 9350994 [Abstract] [Full Text] [Related]
6. Comparative analysis of the proteinase specificity in wild-type and stabilized plasminogen activator inhibitor-1: evidence for contribution of intramolecular flexibility. De Taeye B, Gils A, Vleugels N, Rabijns A, Declerck PJ. Biochem Biophys Res Commun; 2004 Aug 27; 321(3):746-51. PubMed ID: 15358169 [Abstract] [Full Text] [Related]
7. Distal hinge of plasminogen activator inhibitor-1 involves its latency transition and specificities toward serine proteases. Wang Q, Shaltiel S. BMC Biochem; 2003 Jul 08; 4():5. PubMed ID: 12848892 [Abstract] [Full Text] [Related]
11. Immobilization of the distal hinge in the labile serpin plasminogen activator inhibitor 1: identification of a transition state with distinct conformational and functional properties. De Taeye B, Compernolle G, Dewilde M, Biesemans W, Declerck PJ. J Biol Chem; 2003 Jun 27; 278(26):23899-905. PubMed ID: 12686544 [Abstract] [Full Text] [Related]
12. Conformational changes of the reactive-centre loop and beta-strand 5A accompany temperature-dependent inhibitor-substrate transition of plasminogen-activator inhibitor 1. Kjøller L, Martensen PM, Sottrup-Jensen L, Justesen J, Rodenburg KW, Andreasen PA. Eur J Biochem; 1996 Oct 01; 241(1):38-46. PubMed ID: 8898886 [Abstract] [Full Text] [Related]
13. The importance of helix F in plasminogen activator inhibitor-1. Vleugels N, Gils A, Bijnens AP, Knockaert I, Declerck PJ. Biochim Biophys Acta; 2000 Jan 03; 1476(1):20-6. PubMed ID: 10606763 [Abstract] [Full Text] [Related]
14. Importance of the hinge region between alpha-helix F and the main part of serpins, based upon identification of the epitope of plasminogen activator inhibitor type 1 neutralizing antibodies. Bijnens AP, Gils A, Knockaert I, Stassen JM, Declerck PJ. J Biol Chem; 2000 Mar 03; 275(9):6375-80. PubMed ID: 10692438 [Abstract] [Full Text] [Related]
15. A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism. Egelund R, Petersen TE, Andreasen PA. Eur J Biochem; 2001 Feb 03; 268(3):673-85. PubMed ID: 11168406 [Abstract] [Full Text] [Related]
16. Different structural requirements for plasminogen activator inhibitor 1 (PAI-1) during latency transition and proteinase inhibition as evidenced by phage-displayed hypermutated PAI-1 libraries. Stoop AA, Eldering E, Dafforn TR, Read RJ, Pannekoek H. J Mol Biol; 2001 Jan 26; 305(4):773-83. PubMed ID: 11162091 [Abstract] [Full Text] [Related]
17. A novel form of the plasminogen activator inhibitor created by cysteine mutations extends its half-life: relevance to cancer and angiogenesis. Chorostowska-Wynimko J, Swiercz R, Skrzypczak-Jankun E, Wojtowicz A, Selman SH, Jankun J. Mol Cancer Ther; 2003 Jan 26; 2(1):19-28. PubMed ID: 12533669 [Abstract] [Full Text] [Related]
18. Structural determinants in the stability of the serpin/proteinase complex. De Taeye B, Verbeke K, Compernolle G, Biesemans W, Gils A, Declerck PJ. Biochem Biophys Res Commun; 2003 Aug 01; 307(3):529-34. PubMed ID: 12893254 [Abstract] [Full Text] [Related]
19. Alteration of serpin specificity by a protein cofactor. Vitronectin endows plasminogen activator inhibitor 1 with thrombin inhibitory properties. Ehrlich HJ, Gebbink RK, Keijer J, Linders M, Preissner KT, Pannekoek H. J Biol Chem; 1990 Aug 05; 265(22):13029-35. PubMed ID: 1695900 [Abstract] [Full Text] [Related]
20. Effect of stabilizing versus destabilizing interactions on plasminogen activator inhibitor-1. Vleugels N, Leys J, Knockaert I, Declerck PJ. J Pharm Belg; 2000 Aug 05; 55(2):57-8. PubMed ID: 10842928 [Abstract] [Full Text] [Related] Page: [Next] [New Search]