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342 related items for PubMed ID: 9756870

  • 1. Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia.
    Huang Y, Liu XQ, Rall SC, Taylor JM, von Eckardstein A, Assmann G, Mahley RW.
    J Biol Chem; 1998 Oct 09; 273(41):26388-93. PubMed ID: 9756870
    [Abstract] [Full Text] [Related]

  • 2. Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis.
    Huang Y, Ji ZS, Brecht WJ, Rall SC, Taylor JM, Mahley RW.
    Arterioscler Thromb Vasc Biol; 1999 Dec 09; 19(12):2952-9. PubMed ID: 10591675
    [Abstract] [Full Text] [Related]

  • 3. Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins.
    Huang Y, Liu XQ, Rall SC, Mahley RW.
    J Biol Chem; 1998 Jul 10; 273(28):17483-90. PubMed ID: 9651338
    [Abstract] [Full Text] [Related]

  • 4. Hyperlipidemia of ApoE2(Arg(158)-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression.
    van Dijk KW, van Vlijmen BJ, de Winther MP, van 't Hof B, van der Zee A, van der Boom H, Havekes LM, Hofker MH.
    Arterioscler Thromb Vasc Biol; 1999 Dec 10; 19(12):2945-51. PubMed ID: 10591674
    [Abstract] [Full Text] [Related]

  • 5. Structural peculiarities of the binding of very low density lipoproteins and low density lipoproteins to the LDL receptor in hypertriglyceridemia: role of apolipoprotein E.
    Dergunov AD, Smirnova EA, Merched A, Visvikis S, Siest G, Yakushkin VV, Tsibulsky V.
    Biochim Biophys Acta; 2000 Feb 24; 1484(1):29-40. PubMed ID: 10685028
    [Abstract] [Full Text] [Related]

  • 6. Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver.
    Mensenkamp AR, Jong MC, van Goor H, van Luyn MJ, Bloks V, Havinga R, Voshol PJ, Hofker MH, van Dijk KW, Havekes LM, Kuipers F.
    J Biol Chem; 1999 Dec 10; 274(50):35711-8. PubMed ID: 10585451
    [Abstract] [Full Text] [Related]

  • 7. Apolipoprotein E2 (Lys146-->Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides.
    de Beer F, van Dijk KW, Jong MC, van Vark LC, van der Zee A, Hofker MH, Fallaux FJ, Hoeben RC, Smelt AH, Havekes LM.
    Arterioscler Thromb Vasc Biol; 2000 Jul 10; 20(7):1800-6. PubMed ID: 10894820
    [Abstract] [Full Text] [Related]

  • 8. Hepatic lipid accumulation, altered very low density lipoprotein formation and apolipoprotein E deposition in apolipoprotein E3-Leiden transgenic mice.
    Mensenkamp AR, van Luyn MJ, van Goor H, Bloks V, Apostel F, Greeve J, Hofker MH, Jong MC, van Vlijmen BJ, Havekes LM, Kuipers F.
    J Hepatol; 2000 Aug 10; 33(2):189-98. PubMed ID: 10952236
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of lipoprotein lipase induced cholesterol ester accumulation in human hepatoma HepG2 cells.
    Cianflone K, Avramoglu RK, Sawyez C, Huff MW.
    Atherosclerosis; 1996 Feb 10; 120(1-2):101-14. PubMed ID: 8645351
    [Abstract] [Full Text] [Related]

  • 10. Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice.
    Aalto-Setälä K, Weinstock PH, Bisgaier CL, Wu L, Smith JD, Breslow JL.
    J Lipid Res; 1996 Aug 10; 37(8):1802-11. PubMed ID: 8864964
    [Abstract] [Full Text] [Related]

  • 11. Plasma kinetics of apoC-III and apoE in normolipidemic and hypertriglyceridemic subjects.
    Batal R, Tremblay M, Barrett PH, Jacques H, Fredenrich A, Mamer O, Davignon J, Cohn JS.
    J Lipid Res; 2000 May 10; 41(5):706-18. PubMed ID: 10787431
    [Abstract] [Full Text] [Related]

  • 12. Evidence that cholesteryl ester and triglyceride accumulation in J774 macrophages induced by very low density lipoprotein subfractions occurs by different mechanisms.
    Evans AJ, Sawyez CG, Wolfe BM, Connelly PW, Maguire GF, Huff MW.
    J Lipid Res; 1993 May 10; 34(5):703-17. PubMed ID: 8509711
    [Abstract] [Full Text] [Related]

  • 13. Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor.
    van Dijk KW, van Vlijmen BJ, van der Zee A, van't Hof B, van der Boom H, Kobayashi K, Chan L, Havekes LM, Hofker MH.
    Arterioscler Thromb Vasc Biol; 1998 Jan 10; 18(1):7-12. PubMed ID: 9445249
    [Abstract] [Full Text] [Related]

  • 14. Inhibitory effects of specific apolipoprotein C-III isoforms on the binding of triglyceride-rich lipoproteins to the lipolysis-stimulated receptor.
    Mann CJ, Troussard AA, Yen FT, Hannouche N, Najib J, Fruchart JC, Lotteau V, André P, Bihain BE.
    J Biol Chem; 1997 Dec 12; 272(50):31348-54. PubMed ID: 9395464
    [Abstract] [Full Text] [Related]

  • 15. The hypolipidemic action of bezafibrate therapy in hypertriglyceridemia is mediated by upregulation of lipoprotein lipase: no effects on VLDL substrate affinity to lipolysis or LDL receptor binding.
    de Man FH, de Beer F, van der Laarse A, Jansen H, Leuven JA, Souverijn JH, Vroom TF, Schoormans SC, Fruchart JC, Havekes LM, Smelt AH.
    Atherosclerosis; 2000 Dec 12; 153(2):363-71. PubMed ID: 11164425
    [Abstract] [Full Text] [Related]

  • 16. Lipoprotein lipase- and hepatic triglyceride lipase- promoted very low density lipoprotein degradation proceeds via an apolipoprotein E-dependent mechanism.
    Medh JD, Fry GL, Bowen SL, Ruben S, Wong H, Chappell DA.
    J Lipid Res; 2000 Nov 12; 41(11):1858-71. PubMed ID: 11060356
    [Abstract] [Full Text] [Related]

  • 17. Lipolysis is a prerequisite for lipid accumulation in HepG2 cells induced by large hypertriglyceridemic very low density lipoproteins.
    Evans AJ, Sawyez CG, Wolfe BM, Huff MW.
    J Biol Chem; 1992 May 25; 267(15):10743-51. PubMed ID: 1587849
    [Abstract] [Full Text] [Related]

  • 18. Markedly increased secretion of VLDL triglycerides induced by gene transfer of apolipoprotein E isoforms in apoE-deficient mice.
    Tsukamoto K, Maugeais C, Glick JM, Rader DJ.
    J Lipid Res; 2000 Feb 25; 41(2):253-9. PubMed ID: 10681409
    [Abstract] [Full Text] [Related]

  • 19. Apolipoprotein C-III and the metabolic basis for hypertriglyceridemia and the dense low-density lipoprotein phenotype.
    Zheng C, Khoo C, Furtado J, Sacks FM.
    Circulation; 2010 Apr 20; 121(15):1722-34. PubMed ID: 20368524
    [Abstract] [Full Text] [Related]

  • 20. The composition, structural properties and binding of very-low-density and low-density lipoproteins to the LDL receptor in normo- and hypertriglyceridemia: relation to the apolipoprotein E phenotype.
    Dergunov AD, Novoselov AV, Visvikis S, Siest G, Yakushkin VV, Tsibulsky V.
    Biol Chem; 2005 May 20; 386(5):441-52. PubMed ID: 15927888
    [Abstract] [Full Text] [Related]

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