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2. Dual inactivation of RB and p53 pathways in RAS-induced melanomas. Bardeesy N, Bastian BC, Hezel A, Pinkel D, DePinho RA, Chin L. Mol Cell Biol; 2001 Mar; 21(6):2144-53. PubMed ID: 11238948 [Abstract] [Full Text] [Related]
3. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Zhang Y, Xiong Y, Yarbrough WG. Cell; 1998 Mar 20; 92(6):725-34. PubMed ID: 9529249 [Abstract] [Full Text] [Related]
4. Deregulation of the TP53/p14ARF tumor suppressor pathway in low-grade diffuse astrocytomas and its influence on clinical course. Watanabe T, Katayama Y, Yoshino A, Komine C, Yokoyama T. Clin Cancer Res; 2003 Oct 15; 9(13):4884-90. PubMed ID: 14581362 [Abstract] [Full Text] [Related]
5. P16(INK4A) is implicated in both the immediate and adaptative response of human keratinocytes to UVB irradiation. Chazal M, Marionnet C, Michel L, Mollier K, Dazard JE, Della Valle V, Larsen CJ, Gras MP, Basset-Séguin N. Oncogene; 2002 Apr 18; 21(17):2652-61. PubMed ID: 11965538 [Abstract] [Full Text] [Related]
6. p16INK4A and p19ARF act in overlapping pathways in cellular immortalization. Carnero A, Hudson JD, Price CM, Beach DH. Nat Cell Biol; 2000 Mar 18; 2(3):148-55. PubMed ID: 10707085 [Abstract] [Full Text] [Related]
7. Profiles of the 2 INK4a gene products, p16 and p14ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status. Le Frère-Belda MA, Gil Diez de Medina S, Daher A, Martin N, Albaud B, Heudes D, Abbou CC, Thiery JP, Zafrani ES, Radvanyi F, Chopin D. Hum Pathol; 2004 Jul 18; 35(7):817-24. PubMed ID: 15257544 [Abstract] [Full Text] [Related]
8. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Pomerantz J, Schreiber-Agus N, Liégeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C, DePinho RA. Cell; 1998 Mar 20; 92(6):713-23. PubMed ID: 9529248 [Abstract] [Full Text] [Related]
9. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. Stott FJ, Bates S, James MC, McConnell BB, Starborg M, Brookes S, Palmero I, Ryan K, Hara E, Vousden KH, Peters G. EMBO J; 1998 Sep 01; 17(17):5001-14. PubMed ID: 9724636 [Abstract] [Full Text] [Related]
10. ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2. Chang DL, Qiu W, Ying H, Zhang Y, Chen CY, Xiao ZX. Oncogene; 2007 Jul 12; 26(32):4627-34. PubMed ID: 17297463 [Abstract] [Full Text] [Related]
11. The early growth response gene EGR-1 behaves as a suppressor gene that is down-regulated independent of ARF/Mdm2 but not p53 alterations in fresh human gliomas. Calogero A, Arcella A, De Gregorio G, Porcellini A, Mercola D, Liu C, Lombari V, Zani M, Giannini G, Gagliardi FM, Caruso R, Gulino A, Frati L, Ragona G. Clin Cancer Res; 2001 Sep 12; 7(9):2788-96. PubMed ID: 11555594 [Abstract] [Full Text] [Related]
12. Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ. Proc Natl Acad Sci U S A; 1998 Jul 07; 95(14):8292-7. PubMed ID: 9653180 [Abstract] [Full Text] [Related]
13. p53: only ARF the story. Lloyd AC. Nat Cell Biol; 2000 Mar 07; 2(3):E48-50. PubMed ID: 10707099 [Abstract] [Full Text] [Related]
14. Growth suppression by a p14(ARF) exon 1beta adenovirus in human tumor cell lines of varying p53 and Rb status. Saadatmandi N, Tyler T, Huang Y, Haghighi A, Frost G, Borgstrom P, Gjerset RA. Cancer Gene Ther; 2002 Oct 07; 9(10):830-9. PubMed ID: 12224024 [Abstract] [Full Text] [Related]
16. Immunohistochemical inactivation of p14ARF concomitant with MDM2 overexpression inversely correlates with p53 overexpression in oral squamous cell carcinoma. Sano T, Hikino T, Xue Q, Saito T, Kashiwabara K, Oyama T, Nakajima T. Pathol Int; 2000 Sep 07; 50(9):709-16. PubMed ID: 11012984 [Abstract] [Full Text] [Related]
17. CDK4 and MDM2 gene alterations mainly occur in highly proliferative and aggressive mantle cell lymphomas with wild-type INK4a/ARF locus. Hernández L, Beà S, Pinyol M, Ott G, Katzenberger T, Rosenwald A, Bosch F, López-Guillermo A, Delabie J, Colomer D, Montserrat E, Campo E. Cancer Res; 2005 Mar 15; 65(6):2199-206. PubMed ID: 15781632 [Abstract] [Full Text] [Related]
18. P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Tao W, Levine AJ. Proc Natl Acad Sci U S A; 1999 Jun 08; 96(12):6937-41. PubMed ID: 10359817 [Abstract] [Full Text] [Related]
19. [Interactive pathway of ARF-mdm2-p53]. Lin J, Zhu MH. Ai Zheng; 2003 Mar 08; 22(3):328-30. PubMed ID: 12654198 [Abstract] [Full Text] [Related]
20. Rapid asymmetric evolution of a dual-coding tumor suppressor INK4a/ARF locus contradicts its function. Szklarczyk R, Heringa J, Pond SK, Nekrutenko A. Proc Natl Acad Sci U S A; 2007 Jul 31; 104(31):12807-12. PubMed ID: 17652172 [Abstract] [Full Text] [Related] Page: [Next] [New Search]