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Journal Abstract Search

156 related items for PubMed ID: 9761676

  • 1. The nature of antibody heavy chain residue H6 strongly influences the stability of a VH domain lacking the disulfide bridge.
    Langedijk AC, Honegger A, Maat J, Planta RJ, van Schaik RC, Plückthun A.
    J Mol Biol; 1998; 283(1):95-110. PubMed ID: 9761676
    [Abstract] [Full Text] [Related]

  • 2. A natural antibody missing a cysteine in VH: consequences for thermodynamic stability and folding.
    Proba K, Honegger A, Plückthun A.
    J Mol Biol; 1997 Jan 17; 265(2):161-72. PubMed ID: 9020980
    [Abstract] [Full Text] [Related]

  • 3. Mutual stabilization of VL and VH in single-chain antibody fragments, investigated with mutants engineered for stability.
    Wörn A, Plückthun A.
    Biochemistry; 1998 Sep 22; 37(38):13120-7. PubMed ID: 9748318
    [Abstract] [Full Text] [Related]

  • 4. Contributions of a highly conserved VH/VL hydrogen bonding interaction to scFv folding stability and refolding efficiency.
    Tan PH, Sandmaier BM, Stayton PS.
    Biophys J; 1998 Sep 22; 75(3):1473-82. PubMed ID: 9726949
    [Abstract] [Full Text] [Related]

  • 5. Antibody scFv fragments without disulfide bonds made by molecular evolution.
    Proba K, Wörn A, Honegger A, Plückthun A.
    J Mol Biol; 1998 Jan 16; 275(2):245-53. PubMed ID: 9466907
    [Abstract] [Full Text] [Related]

  • 6. The importance of framework residues H6, H7 and H10 in antibody heavy chains: experimental evidence for a new structural subclassification of antibody V(H) domains.
    Jung S, Spinelli S, Schimmele B, Honegger A, Pugliese L, Cambillau C, Plückthun A.
    J Mol Biol; 2001 Jun 08; 309(3):701-16. PubMed ID: 11397090
    [Abstract] [Full Text] [Related]

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  • 8. Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.
    Saerens D, Conrath K, Govaert J, Muyldermans S.
    J Mol Biol; 2008 Mar 21; 377(2):478-88. PubMed ID: 18262543
    [Abstract] [Full Text] [Related]

  • 9. Critical interactions in binding antibody NC41 to influenza N9 neuraminidase: amino acid contacts on the antibody heavy chain.
    Pruett PS, Air GM.
    Biochemistry; 1998 Jul 28; 37(30):10660-70. PubMed ID: 9692956
    [Abstract] [Full Text] [Related]

  • 10. DNA binding by the VH domain of anti-Z-DNA antibody and its modulation by association of the VL domain.
    Chen Y, Stollar BD.
    J Immunol; 1999 Apr 15; 162(8):4663-70. PubMed ID: 10202006
    [Abstract] [Full Text] [Related]

  • 11. Conformations of the third hypervariable region in the VH domain of immunoglobulins.
    Morea V, Tramontano A, Rustici M, Chothia C, Lesk AM.
    J Mol Biol; 1998 Jan 16; 275(2):269-94. PubMed ID: 9466909
    [Abstract] [Full Text] [Related]

  • 12. Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule.
    Ouellette D, Alessandri L, Chin A, Grinnell C, Tarcsa E, Radziejewski C, Correia I.
    Anal Biochem; 2010 Feb 01; 397(1):37-47. PubMed ID: 19766583
    [Abstract] [Full Text] [Related]

  • 13. Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability.
    Röthlisberger D, Honegger A, Plückthun A.
    J Mol Biol; 2005 Apr 08; 347(4):773-89. PubMed ID: 15769469
    [Abstract] [Full Text] [Related]

  • 14. [Recombinant design and expression of human three-domain antibody against BoNTa].
    Wang H, Yin J, Shi J, Meng LL, Li PZ.
    Wei Sheng Wu Xue Bao; 2005 Apr 08; 45(2):223-5. PubMed ID: 15989265
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  • 16. The scFv fragment of the antibody hu4D5-8: evidence for early premature domain interaction in refolding.
    Jäger M, Gehrig P, Plückthun A.
    J Mol Biol; 2001 Feb 02; 305(5):1111-29. PubMed ID: 11162118
    [Abstract] [Full Text] [Related]

  • 17. Folding and oxidation of the antibody domain C(H)3.
    Thies MJ, Talamo F, Mayer M, Bell S, Ruoppolo M, Marino G, Buchner J.
    J Mol Biol; 2002 Jun 21; 319(5):1267-77. PubMed ID: 12079363
    [Abstract] [Full Text] [Related]

  • 18. Structural characterization of mouse monoclonal antibody 13-1 against a porphyrin derivative: identification of a disulfide bond in CDR-H3 of Mab 13-1.
    Akashi S, Kato K, Torizawa T, Dohmae N, Yamaguchi H, Kamachi M, Harada A, Imanaka T, Shimada I, Takio K.
    Biochem Biophys Res Commun; 1997 Nov 26; 240(3):566-72. PubMed ID: 9398605
    [Abstract] [Full Text] [Related]

  • 19. Improving the stability of an antibody variable fragment by a combination of knowledge-based approaches: validation and mechanisms.
    Monsellier E, Bedouelle H.
    J Mol Biol; 2006 Sep 22; 362(3):580-93. PubMed ID: 16926023
    [Abstract] [Full Text] [Related]

  • 20. The influence of the buried glutamine or glutamate residue in position 6 on the structure of immunoglobulin variable domains.
    Honegger A, Plückthun A.
    J Mol Biol; 2001 Jun 08; 309(3):687-99. PubMed ID: 11397089
    [Abstract] [Full Text] [Related]

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