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557 related items for PubMed ID: 9761740

  • 41. Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src).
    Lebrun P, Mothe-Satney I, Delahaye L, Van Obberghen E, Baron V.
    J Biol Chem; 1998 Nov 27; 273(48):32244-53. PubMed ID: 9822703
    [Abstract] [Full Text] [Related]

  • 42. Contraction inhibits insulin-stimulated insulin receptor substrate-1/2-associated phosphoinositide 3-kinase activity, but not protein kinase B activation or glucose uptake, in rat muscle.
    Whitehead JP, Soos MA, Aslesen R, O'rahilly S, Jensen J.
    Biochem J; 2000 Aug 01; 349 Pt 3(Pt 3):775-81. PubMed ID: 10903138
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  • 43. Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1.
    Sánchez-Margalet V, Goldfine ID, Truitt K, Imboden J, Sung CK.
    Mol Endocrinol; 1995 Apr 01; 9(4):435-42. PubMed ID: 7659087
    [Abstract] [Full Text] [Related]

  • 44. Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.
    Goldstein BJ, Bittner-Kowalczyk A, White MF, Harbeck M.
    J Biol Chem; 2000 Feb 11; 275(6):4283-9. PubMed ID: 10660596
    [Abstract] [Full Text] [Related]

  • 45. A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes.
    Gesbert F, Guenzi C, Bertoglio J.
    J Biol Chem; 1998 Jul 17; 273(29):18273-81. PubMed ID: 9660791
    [Abstract] [Full Text] [Related]

  • 46. Prolonged vs transient roles for early cell cycle signaling components.
    Rose DW, Xiao S, Pillay TS, Kolch W, Olefsky JM.
    Oncogene; 1998 Aug 20; 17(7):889-99. PubMed ID: 9780005
    [Abstract] [Full Text] [Related]

  • 47. Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling.
    Kim SO, Jiang J, Yi W, Feng GS, Frank SJ.
    J Biol Chem; 1998 Jan 23; 273(4):2344-54. PubMed ID: 9442080
    [Abstract] [Full Text] [Related]

  • 48. Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2.
    Tobe K, Matuoka K, Tamemoto H, Ueki K, Kaburagi Y, Asai S, Noguchi T, Matsuda M, Tanaka S, Hattori S.
    J Biol Chem; 1993 May 25; 268(15):11167-71. PubMed ID: 8388384
    [Abstract] [Full Text] [Related]

  • 49. The regulatory mechanism of phosphatidylinositol 3-kinase by insulin in 3T3 L1 fibroblasts: phosphorylation-independent activation of phosphatidylinositol 3-kinase.
    Kang I, Choi SL, Kim SS, Kim SJ, Ha J, Oh SM, Kim SS.
    Exp Mol Med; 1998 Dec 31; 30(4):263-9. PubMed ID: 9894159
    [Abstract] [Full Text] [Related]

  • 50. Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit.
    Rordorf-Nikolic T, Van Horn DJ, Chen D, White MF, Backer JM.
    J Biol Chem; 1995 Feb 24; 270(8):3662-6. PubMed ID: 7876105
    [Abstract] [Full Text] [Related]

  • 51. The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling.
    Myers MG, Mendez R, Shi P, Pierce JH, Rhoads R, White MF.
    J Biol Chem; 1998 Oct 09; 273(41):26908-14. PubMed ID: 9756938
    [Abstract] [Full Text] [Related]

  • 52. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4640-5. PubMed ID: 11287630
    [Abstract] [Full Text] [Related]

  • 53. Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action.
    Deng Y, Bhattacharya S, Swamy OR, Tandon R, Wang Y, Janda R, Riedel H.
    J Biol Chem; 2003 Oct 10; 278(41):39311-22. PubMed ID: 12783867
    [Abstract] [Full Text] [Related]

  • 54. Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes.
    Egawa K, Nakashima N, Sharma PM, Maegawa H, Nagai Y, Kashiwagi A, Kikkawa R, Olefsky JM.
    Endocrinology; 2000 Jun 10; 141(6):1930-5. PubMed ID: 10830273
    [Abstract] [Full Text] [Related]

  • 55. YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.
    Myers MG, Zhang Y, Aldaz GA, Grammer T, Glasheen EM, Yenush L, Wang LM, Sun XJ, Blenis J, Pierce JH, White MF.
    Mol Cell Biol; 1996 Aug 10; 16(8):4147-55. PubMed ID: 8754813
    [Abstract] [Full Text] [Related]

  • 56. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM, Lorenzo M, Pons S, White MF, Benito M.
    Mol Endocrinol; 1998 May 10; 12(5):688-97. PubMed ID: 9605931
    [Abstract] [Full Text] [Related]

  • 57. Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62, and GTPase-activating protein.
    Sung CK, Sánchez-Margalet V, Goldfine ID.
    J Biol Chem; 1994 Apr 29; 269(17):12503-7. PubMed ID: 8175658
    [Abstract] [Full Text] [Related]

  • 58. 14-3-3beta protein associates with insulin receptor substrate 1 and decreases insulin-stimulated phosphatidylinositol 3'-kinase activity in 3T3L1 adipocytes.
    Kosaki A, Yamada K, Suga J, Otaka A, Kuzuya H.
    J Biol Chem; 1998 Jan 09; 273(2):940-4. PubMed ID: 9422753
    [Abstract] [Full Text] [Related]

  • 59. Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP.
    Staubs PA, Reichart DR, Saltiel AR, Milarski KL, Maegawa H, Berhanu P, Olefsky JM, Seely BL.
    J Biol Chem; 1994 Nov 04; 269(44):27186-92. PubMed ID: 7525547
    [Abstract] [Full Text] [Related]

  • 60. Multiple signaling pathways mediate interleukin-4-induced 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene expression in human breast cancer cells.
    Gingras S, Côté S, Simard J.
    Mol Endocrinol; 2000 Feb 04; 14(2):229-40. PubMed ID: 10674396
    [Abstract] [Full Text] [Related]

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