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165 related items for PubMed ID: 9762350
1. Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase. Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC. Adv Enzyme Regul; 1998; 38():111-33. PubMed ID: 9762350 [Abstract] [Full Text] [Related]
2. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1. Keyes SR, Fracasso PM, Heimbrook DC, Rockwell S, Sligar SG, Sartorelli AC. Cancer Res; 1984 Dec; 44(12 Pt 1):5638-43. PubMed ID: 6437671 [Abstract] [Full Text] [Related]
3. Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase. Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC. Proc Natl Acad Sci U S A; 1996 Jan 09; 93(1):456-60. PubMed ID: 8552660 [Abstract] [Full Text] [Related]
4. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells. Baumann RP, Hodnick WF, Seow HA, Belcourt MF, Rockwell S, Sherman DH, Sartorelli AC. Cancer Res; 2001 Nov 01; 61(21):7770-6. PubMed ID: 11691791 [Abstract] [Full Text] [Related]
5. Bioactivation of mitomycin antibiotics by aerobic and hypoxic Chinese hamster ovary cells overexpressing DT-diaphorase. Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC. Biochem Pharmacol; 1996 Jun 28; 51(12):1669-78. PubMed ID: 8687482 [Abstract] [Full Text] [Related]
6. Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C. Keyes SR, Heimbrook DC, Fracasso PM, Rockwell S, Sligar SG, Sartorelli AC. Adv Enzyme Regul; 1985 Jun 28; 23():291-307. PubMed ID: 3934922 [Abstract] [Full Text] [Related]
7. Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9. Fitzsimmons SA, Workman P, Grever M, Paull K, Camalier R, Lewis AD. J Natl Cancer Inst; 1996 Mar 06; 88(5):259-69. PubMed ID: 8614004 [Abstract] [Full Text] [Related]
8. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase. Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A. Cancer Chemother Pharmacol; 2002 Feb 06; 49(2):101-10. PubMed ID: 11862423 [Abstract] [Full Text] [Related]
9. Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones. Gustafson DL, Beall HD, Bolton EM, Ross D, Waldren CA. Mol Pharmacol; 1996 Oct 06; 50(4):728-35. PubMed ID: 8863816 [Abstract] [Full Text] [Related]
10. Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual. Marshall RS, Paterson MC, Rauth AM. Biochem Pharmacol; 1991 May 01; 41(9):1351-60. PubMed ID: 1902110 [Abstract] [Full Text] [Related]
11. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells. Fracasso PM, Sartorelli AC. Cancer Res; 1986 Aug 01; 46(8):3939-44. PubMed ID: 3089583 [Abstract] [Full Text] [Related]
12. Chinese hamster ovary cell lines resistant to mitomycin C under aerobic but not hypoxic conditions are deficient in DT-diaphorase. Dulhanty AM, Whitmore GF. Cancer Res; 1991 Apr 01; 51(7):1860-5. PubMed ID: 1900739 [Abstract] [Full Text] [Related]
13. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions. Begleiter A, Leith MK. Mol Pharmacol; 1993 Jul 01; 44(1):210-5. PubMed ID: 8341273 [Abstract] [Full Text] [Related]
14. Decreased NADPH:cytochrome P-450 reductase activity and impaired drug activation in a mammalian cell line resistant to mitomycin C under aerobic but not hypoxic conditions. Hoban PR, Walton MI, Robson CN, Godden J, Stratford IJ, Workman P, Harris AL, Hickson ID. Cancer Res; 1990 Aug 01; 50(15):4692-7. PubMed ID: 2114946 [Abstract] [Full Text] [Related]
15. pH-dependent inactivation of DT-diaphorase by mitomycin C and porfiromycin. Siegel D, Beall H, Kasai M, Arai H, Gibson NW, Ross D. Mol Pharmacol; 1993 Dec 01; 44(6):1128-34. PubMed ID: 8264549 [Abstract] [Full Text] [Related]
16. DT-diaphorase protects cells from the hypoxic cytotoxicity of indoloquinone EO9. Plumb JA, Gerritsen M, Workman P. Br J Cancer; 1994 Dec 01; 70(6):1136-43. PubMed ID: 7526885 [Abstract] [Full Text] [Related]
17. [DT-diaphorase]. Mikami K, Shirakusa T, Tsuruo T. Gan To Kagaku Ryoho; 1997 Sep 01; 24(11):1606-10. PubMed ID: 9309161 [Abstract] [Full Text] [Related]
18. Current issues in the enzymology of mitomycin C metabolic activation. Spanswick VJ, Cummings J, Smyth JF. Gen Pharmacol; 1998 Oct 01; 31(4):539-44. PubMed ID: 9792212 [Abstract] [Full Text] [Related]
19. The intracellular location of NADH:cytochrome b5 reductase modulates the cytotoxicity of the mitomycins to Chinese hamster ovary cells. Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC. J Biol Chem; 1998 Apr 10; 273(15):8875-81. PubMed ID: 9535868 [Abstract] [Full Text] [Related]
20. Cellular approaches to bioreductive drug mechanisms. Rauth AM, Marshall RS, Kuehl BL. Cancer Metastasis Rev; 1993 Jun 10; 12(2):153-64. PubMed ID: 8375018 [Abstract] [Full Text] [Related] Page: [Next] [New Search]