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Journal Abstract Search


317 related items for PubMed ID: 9763403

  • 1. Disposition of the antipsychotic agent CI-1007 in rats, monkeys, dogs, and human cytochrome P450 2D6 extensive metabolizers. Species comparison and allometric scaling.
    Feng MR, Loo J, Wright J.
    Drug Metab Dispos; 1998 Oct; 26(10):982-8. PubMed ID: 9763403
    [Abstract] [Full Text] [Related]

  • 2. Metabolism and disposition of novel des-fluoro quinolone garenoxacin in experimental animals and an interspecies scaling of pharmacokinetic parameters.
    Hayakawa H, Fukushima Y, Kato H, Fukumoto H, Kadota T, Yamamoto H, Kuroiwa H, Nishigaki J, Tsuji A.
    Drug Metab Dispos; 2003 Nov; 31(11):1409-18. PubMed ID: 14570774
    [Abstract] [Full Text] [Related]

  • 3. Metabolic disposition of 6-ethyl-3-(1H-tetrazol-5-yl)-chromone, a new antiallergic agent, in the rat, guinea-pig, rabbit, dog and monkey.
    Kanai Y, Nakai Y, Nakajima N, Tanayama S.
    Xenobiotica; 1979 Jan; 9(1):33-50. PubMed ID: 104449
    [Abstract] [Full Text] [Related]

  • 4. Comparative metabolism of radiolabeled muraglitazar in animals and humans by quantitative and qualitative metabolite profiling.
    Zhang D, Wang L, Raghavan N, Zhang H, Li W, Cheng PT, Yao M, Zhang L, Zhu M, Bonacorsi S, Yeola S, Mitroka J, Hariharan N, Hosagrahara V, Chandrasena G, Shyu WC, Humphreys WG.
    Drug Metab Dispos; 2007 Jan; 35(1):150-67. PubMed ID: 17062777
    [Abstract] [Full Text] [Related]

  • 5. Metabolic disposition of the cognition activator tacrine in rats, dogs, and humans. Species comparisons.
    Pool WF, Reily MD, Bjorge SM, Woolf TF.
    Drug Metab Dispos; 1997 May; 25(5):590-7. PubMed ID: 9152598
    [Abstract] [Full Text] [Related]

  • 6. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans.
    Zhang D, He K, Raghavan N, Wang L, Mitroka J, Maxwell BD, Knabb RM, Frost C, Schuster A, Hao F, Gu Z, Humphreys WG, Grossman SJ.
    Drug Metab Dispos; 2009 Aug; 37(8):1738-48. PubMed ID: 19420130
    [Abstract] [Full Text] [Related]

  • 7. Disposition and metabolism of rifapentine, a rifamycin antibiotic, in mice, rats, and monkeys.
    Emary WB, Toren PC, Mathews B, Huh K.
    Drug Metab Dispos; 1998 Aug; 26(8):725-31. PubMed ID: 9698285
    [Abstract] [Full Text] [Related]

  • 8. Excretion and metabolism of recainam, a new anti-arrhythmic drug, in laboratory animals and humans.
    Scatina JA, Wells DS, Kimmel HB, Kemper CJ, Sisenwine SF.
    Drug Metab Dispos; 1990 Aug; 18(5):746-52. PubMed ID: 1981731
    [Abstract] [Full Text] [Related]

  • 9. Species differences in the metabolism and disposition of spironolactone.
    Karim A, Kook C, Zitzewitz DJ, Zagarella J, Doherty M, Campion J.
    Drug Metab Dispos; 1976 Aug; 4(6):547-55. PubMed ID: 11976
    [Abstract] [Full Text] [Related]

  • 10. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS, Hatch HL, Kosea F, Nguyen HT, Choo EF, McClure KF, Taylor TJ, Henne KR, Kuperman AV, Dombroski MA, Letavic MA.
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
    [Abstract] [Full Text] [Related]

  • 11. Physiological disposition and metabolic fate of a new antiarrhythmic agent, alpha, alpha-dimethyl-4-(alpha, alpha, beta, beta-tetrafluorophenethyl) benzylamine in the rat, dog, monkey, baboon, and man.
    Zacchei AG, Weidner LL, Besselaar GH, Raftery EB.
    Drug Metab Dispos; 1976 Nov; 4(4):387-401. PubMed ID: 8295
    [Abstract] [Full Text] [Related]

  • 12. Metabolism of MK-499, a class III antiarrhythmic agent, in rats and dogs.
    Vickers S, Duncan CA, Slaughter DE, Arison BH, Greber T, Olah TV, Vyas KP.
    Drug Metab Dispos; 1998 May; 26(5):388-95. PubMed ID: 9571219
    [Abstract] [Full Text] [Related]

  • 13. Disposition of a new nonsteroidal anti-inflammatory agent, S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid, in rats, dogs and monkeys.
    Konishi T, Okada S, Nishikawa H, Esumi Y, Kitamura S, Tatsumi K.
    Arzneimittelforschung; 1998 Mar; 48(3):266-74. PubMed ID: 9553685
    [Abstract] [Full Text] [Related]

  • 14. Metabolic fate of the new angiotensin-converting enzyme inhibitor imidapril in animals. 6th communication: interspecies comparison of pharmacokinetics and excretion of imidapril metabolites in rats, dogs, and monkeys.
    Yamada Y, Endo M, Kohno M, Otsuka M, Takaiti O.
    Arzneimittelforschung; 1992 Apr; 42(4):499-506. PubMed ID: 1642673
    [Abstract] [Full Text] [Related]

  • 15. Pharmacokinetics and systemic bioavailability of menogaril, an anthracycline antitumor agent, in the mouse, dog, and monkey.
    Adams WJ, McGovren JP, Dalm EA, Brewer JE, Hosley JD.
    Cancer Res; 1989 Nov 15; 49(22):6328-36. PubMed ID: 2529962
    [Abstract] [Full Text] [Related]

  • 16. Disposition of remoxipride in different species. Species differences in metabolism.
    Widman M, Nilsson LB, Bryske B, Lundström J.
    Arzneimittelforschung; 1993 Mar 15; 43(3):287-97. PubMed ID: 8489555
    [Abstract] [Full Text] [Related]

  • 17. The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs.
    Huskey SE, Dean BJ, Doss GA, Wang Z, Hop CE, Anari R, Finke PE, Robichaud AJ, Zhang M, Wang B, Strauss JR, Cunningham PK, Feeney WP, Franklin RB, Baillie TA, Chiu SH.
    Drug Metab Dispos; 2004 Feb 15; 32(2):246-58. PubMed ID: 14744948
    [Abstract] [Full Text] [Related]

  • 18. Studies on the metabolism and disposition of the new retinoid 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl] benzoic acid. 4th communication: absorption, metabolism, excretion and plasma protein binding in various animals and man.
    Mizojiri K, Okabe H, Sugeno K, Misaki A, Ito M, Kominami G, Esumi Y, Takaichi M, Harada T, Seki H, Inaba A.
    Arzneimittelforschung; 1997 Mar 15; 47(3):259-69. PubMed ID: 9105544
    [Abstract] [Full Text] [Related]

  • 19. Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor.
    Lin JH, Chiba M, Balani SK, Chen IW, Kwei GY, Vastag KJ, Nishime JA.
    Drug Metab Dispos; 1996 Oct 15; 24(10):1111-20. PubMed ID: 8894513
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of [carbonyl-14C]mosapride citrate after a single oral administration in rats, dogs and monkeys.
    Matsumoto S, Yoshida K, Itogawa A, Tagawa M, Fujii T, Miyazaki H, Sekine Y.
    Arzneimittelforschung; 1993 Oct 15; 43(10):1095-102. PubMed ID: 8267676
    [Abstract] [Full Text] [Related]


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