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127 related items for PubMed ID: 9765505

  • 1. Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs.
    Coxon FP, Benford HL, Russell RG, Rogers MJ.
    Mol Pharmacol; 1998 Oct; 54(4):631-8. PubMed ID: 9765505
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases.
    Dunford JE, Rogers MJ, Ebetino FH, Phipps RJ, Coxon FP.
    J Bone Miner Res; 2006 May; 21(5):684-94. PubMed ID: 16734383
    [Abstract] [Full Text] [Related]

  • 3. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.
    Luckman SP, Hughes DE, Coxon FP, Graham R, Russell G, Rogers MJ.
    J Bone Miner Res; 1998 Apr; 13(4):581-9. PubMed ID: 9556058
    [Abstract] [Full Text] [Related]

  • 4. The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
    Shipman CM, Croucher PI, Russell RG, Helfrich MH, Rogers MJ.
    Cancer Res; 1998 Dec 01; 58(23):5294-7. PubMed ID: 9850051
    [Abstract] [Full Text] [Related]

  • 5. Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-alpha in IEC-6 cells.
    Bhattacharya S, Ray RM, Viar MJ, Johnson LR.
    Am J Physiol Gastrointest Liver Physiol; 2003 Nov 01; 285(5):G980-91. PubMed ID: 12869386
    [Abstract] [Full Text] [Related]

  • 6. Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression.
    Fulda S, Meyer E, Debatin KM.
    Cancer Res; 2000 Jul 15; 60(14):3947-56. PubMed ID: 10919673
    [Abstract] [Full Text] [Related]

  • 7. Opposite effects of flurbiprofen and the nitroxybutyl ester of flurbiprofen on apoptosis in cultured guinea-pig gastric mucous cells.
    Johal K, Hanson PJ.
    Br J Pharmacol; 2000 Jun 15; 130(4):811-8. PubMed ID: 10864887
    [Abstract] [Full Text] [Related]

  • 8. Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells.
    Oades GM, Senaratne SG, Clarke IA, Kirby RS, Colston KW.
    J Urol; 2003 Jul 15; 170(1):246-52. PubMed ID: 12796698
    [Abstract] [Full Text] [Related]

  • 9. Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.
    Choi WS, Canzoniero LM, Sensi SL, O'Malley KL, Gwag BJ, Sohn S, Kim JE, Oh TH, Lee EB, Oh YJ.
    Exp Neurol; 1999 Sep 15; 159(1):274-82. PubMed ID: 10486196
    [Abstract] [Full Text] [Related]

  • 10. Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release.
    Slee EA, Keogh SA, Martin SJ.
    Cell Death Differ; 2000 Jun 15; 7(6):556-65. PubMed ID: 10822279
    [Abstract] [Full Text] [Related]

  • 11. Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells.
    Gamen S, Anel A, Pérez-Galán P, Lasierra P, Johnson D, Piñeiro A, Naval J.
    Exp Cell Res; 2000 Jul 10; 258(1):223-35. PubMed ID: 10912804
    [Abstract] [Full Text] [Related]

  • 12. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide.
    Mizumoto K, Rothman RJ, Farber JL.
    Mol Pharmacol; 1994 Nov 10; 46(5):890-5. PubMed ID: 7969076
    [Abstract] [Full Text] [Related]

  • 13. Apoptotic changes preceding necrosis in lipopolysaccharide-treated macrophages in the presence of cycloheximide.
    Karahashi H, Amano F.
    Exp Cell Res; 1998 Jun 15; 241(2):373-83. PubMed ID: 9637779
    [Abstract] [Full Text] [Related]

  • 14. Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-alpha.
    Stanic I, Facchini A, Borzì RM, Vitellozzi R, Stefanelli C, Goldring MB, Guarnieri C, Facchini A, Flamigni F.
    J Cell Physiol; 2006 Jan 15; 206(1):138-46. PubMed ID: 15965903
    [Abstract] [Full Text] [Related]

  • 15. Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents.
    Zisterer DM, Campiani G, Nacci V, Williams DC.
    J Pharmacol Exp Ther; 2000 Apr 15; 293(1):48-59. PubMed ID: 10734152
    [Abstract] [Full Text] [Related]

  • 16. Intracellular mechanisms mediating tocotrienol-induced apoptosis in neoplastic mammary epithelial cells.
    Sylvester PW, Shah S.
    Asia Pac J Clin Nutr; 2005 Apr 15; 14(4):366-73. PubMed ID: 16326643
    [Abstract] [Full Text] [Related]

  • 17. Butyrate mediates Caco-2 cell apoptosis via up-regulation of pro-apoptotic BAK and inducing caspase-3 mediated cleavage of poly-(ADP-ribose) polymerase (PARP).
    Ruemmele FM, Dionne S, Qureshi I, Sarma DS, Levy E, Seidman EG.
    Cell Death Differ; 1999 Aug 15; 6(8):729-35. PubMed ID: 10467346
    [Abstract] [Full Text] [Related]

  • 18. Teratogen-induced activation of the mitochondrial apoptotic pathway in the yolk sac of day 9 mouse embryos.
    Soleman D, Cornel L, Little SA, Mirkes PE.
    Birth Defects Res A Clin Mol Teratol; 2003 Feb 15; 67(2):98-107. PubMed ID: 12769505
    [Abstract] [Full Text] [Related]

  • 19. Detection of apoptosis induced by topoisomerase inhibitors and serum deprivation in syrian hamster embryo cells.
    Alexandre S, Rast C, Nguyen-Ba G, Vasseur P.
    Exp Cell Res; 2000 Feb 25; 255(1):30-9. PubMed ID: 10666331
    [Abstract] [Full Text] [Related]

  • 20. Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.
    Egger L, Schneider J, Rhême C, Tapernoux M, Häcki J, Borner C.
    Cell Death Differ; 2003 Oct 25; 10(10):1188-203. PubMed ID: 14502242
    [Abstract] [Full Text] [Related]

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