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125 related items for PubMed ID: 9772285

  • 1. Specific induction of hepatocellular adenomas by transplacental administration of ENU in the tsc2 gene mutant (Eker) rat.
    Fukuda T, Mitani H, Tsutsumi M, Konishi Y, Hino O.
    Int J Oncol; 1998 Nov; 13(5):957-61. PubMed ID: 9772285
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  • 2. Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model.
    Kobayashi T, Urakami S, Hirayama Y, Yamamoto T, Nishizawa M, Takahara T, Kubo Y, Hino O.
    Jpn J Cancer Res; 1997 Mar; 88(3):254-61. PubMed ID: 9140109
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  • 3. Presence of a modifier gene(s) affecting early renal carcinogenesis in the Tsc2 mutant (Eker) rat model.
    Kikuchi Y, Sudo A, Mitani H, Hino O.
    Int J Oncol; 2004 Jan; 24(1):75-80. PubMed ID: 14654943
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  • 4. N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat.
    Satake N, Miyagawa M, Sakurai J, Mitani H, Kobayashi T, Tamura H, Hino O.
    Cancer Lett; 2002 Oct 28; 184(2):157-63. PubMed ID: 12127687
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  • 5. Somatic mutation of the tuberous sclerosis (Tsc2) tumor suppressor gene in chemically induced rat renal carcinoma cell.
    Urakami S, Tokuzen R, Tsuda H, Igawa M, Hino O.
    J Urol; 1997 Jul 28; 158(1):275-8. PubMed ID: 9186374
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  • 6. Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells.
    Orimoto K, Tsuchiya H, Kobayashi T, Matsuda T, Hino O.
    Biochem Biophys Res Commun; 1996 Feb 06; 219(1):70-5. PubMed ID: 8619830
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  • 7. Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-type Tsc2 gene.
    Kobayashi T, Mitani H, Takahashi R, Hirabayashi M, Ueda M, Tamura H, Hino O.
    Proc Natl Acad Sci U S A; 1997 Apr 15; 94(8):3990-3. PubMed ID: 9108092
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  • 8. Estrogen treatment enhances hereditary renal tumor development in Eker rats.
    Wolf DC, Goldsworthy TL, Donner EM, Harden R, Fitzpatrick B, Everitt JI.
    Carcinogenesis; 1998 Nov 15; 19(11):2043-7. PubMed ID: 9855022
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  • 9. Distribution of Tsc2 protein in various normal rat tissues and renal tumours of Tsc2 mutant (Eker) rat detected by immunohistochemistry.
    Fukuda T, Kobayashi T, Yasui H, Tsutsumi M, Konishi Y, Hino O.
    Virchows Arch; 1999 Apr 15; 434(4):341-50. PubMed ID: 10335945
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  • 10. Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2).
    Hino O, Kobayashi E, Hirayama Y, Kobayashi T, Kubo Y, Tsuchiya H, Kikuchi Y, Mitani H.
    Mol Carcinog; 1995 Sep 15; 14(1):23-7. PubMed ID: 7546221
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  • 12. Allelic loss at the tuberous sclerosis (Tsc2) gene locus in spontaneous uterine leiomyosarcomas and pituitary adenomas in the Eker rat model.
    Kubo Y, Kikuchi Y, Mitani H, Kobayashi E, Kobayashi T, Hino O.
    Jpn J Cancer Res; 1995 Sep 15; 86(9):828-32. PubMed ID: 7591959
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  • 14. Analysis of preneoplastic and neoplastic renal lesions in Tsc2 mutant Long-Evans (Eker) rats following exposure to a mixture of drinking water disinfection by-products.
    McDorman KS, Hooth MJ, Starr TB, Wolf DC.
    Toxicology; 2003 May 01; 187(1):1-12. PubMed ID: 12679048
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  • 16. Suppression of cytochrome P450 1A1 and 4A1 gene expression in renal carcinomas of TSC2 gene mutant (Eker) rats.
    Okamoto T, Momose S, Hino O.
    Int J Oncol; 2001 Jan 01; 18(1):147-9. PubMed ID: 11115552
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  • 18. Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.
    Kobayashi T, Minowa O, Kuno J, Mitani H, Hino O, Noda T.
    Cancer Res; 1999 Mar 15; 59(6):1206-11. PubMed ID: 10096549
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  • 19. Hereditary renal cell carcinoma in the Eker rat: a unique animal model for the study of cancer susceptibility.
    Everitt JI, Goldsworthy TL, Wolf DC, Walker CL.
    Toxicol Lett; 1995 Dec 15; 82-83():621-5. PubMed ID: 8597118
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  • 20. The carcinogenic response of Tsc2 mutant Long-Evans (Eker) rats to a mixture of drinking water disinfection by-products was less than additive.
    Hooth MJ, McDorman KS, Hester SD, George MH, Brooks LR, Swank AE, Wolf DC.
    Toxicol Sci; 2002 Oct 15; 69(2):322-31. PubMed ID: 12377981
    [Abstract] [Full Text] [Related]

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