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125 related items for PubMed ID: 9772285

  • 21. Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model.
    Tsuchiya H, Orimoto K, Kobayashi K, Hino O.
    Cancer Res; 1996 Feb 01; 56(3):429-33. PubMed ID: 8564946
    [Abstract] [Full Text] [Related]

  • 22. The transcriptional profile of the kidney in Tsc2 heterozygous mutant Long Evans (Eker) rats compared to wild-type.
    Sen B, Wolf DC, Hester SD.
    Mutat Res; 2004 May 18; 549(1-2):213-24. PubMed ID: 15120972
    [Abstract] [Full Text] [Related]

  • 23. Carcinogen-specific gene expression profiles in short-term treated Eker and wild-type rats indicative of pathways involved in renal tumorigenesis.
    Stemmer K, Ellinger-Ziegelbauer H, Ahr HJ, Dietrich DR.
    Cancer Res; 2007 May 01; 67(9):4052-68. PubMed ID: 17483316
    [Abstract] [Full Text] [Related]

  • 24. Identification of cDNAs induced by the tumor suppressor Tsc2 gene using a conditional expression system in Tsc2 mutant (Eker) rat renal carcinoma cells.
    Orimoto K, Tsuchiya H, Sakurai J, Nishizawa M, Hino O.
    Biochem Biophys Res Commun; 1998 Jun 29; 247(3):728-33. PubMed ID: 9647762
    [Abstract] [Full Text] [Related]

  • 25. TSC2 gene mutant (Eker) rat model of a Mendelian dominantly inherited cancer.
    Hino O, Fukuda T, Satake N, Kobayashi T, Honda S, Orimoto K, Yamashita Y, Kikuchi Y.
    Prog Exp Tumor Res; 1999 Jun 29; 35():95-108. PubMed ID: 10377754
    [No Abstract] [Full Text] [Related]

  • 26. Development of high-grade renal cell carcinomas in rats independently of somatic mutations in the Tsc2 and VHL tumor suppressor genes.
    Toyokuni S, Okada K, Kondo S, Nishioka H, Tanaka T, Nishiyama Y, Hino O, Hiai H.
    Jpn J Cancer Res; 1998 Aug 29; 89(8):814-20. PubMed ID: 9765616
    [Abstract] [Full Text] [Related]

  • 27. Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region.
    Jin F, Wienecke R, Xiao GH, Maize JC, DeClue JE, Yeung RS.
    Proc Natl Acad Sci U S A; 1996 Aug 20; 93(17):9154-9. PubMed ID: 8799170
    [Abstract] [Full Text] [Related]

  • 28. Abnormal cortical cells and astrocytomas in the Eker rat model of tuberous sclerosis complex.
    Takahashi DK, Dinday MT, Barbaro NM, Baraban SC.
    Epilepsia; 2004 Dec 20; 45(12):1525-30. PubMed ID: 15571510
    [Abstract] [Full Text] [Related]

  • 29. Interstitial chromosomal deletion of the tuberous sclerosis complex 2 locus is a signature for radiation-associated renal tumors in Eker rats.
    Inoue T, Kokubo T, Daino K, Yanagihara H, Watanabe F, Tsuruoka C, Amasaki Y, Morioka T, Homma-Takeda S, Kobayashi T, Hino O, Shimada Y, Kakinuma S.
    Cancer Sci; 2020 Mar 20; 111(3):840-848. PubMed ID: 31925975
    [Abstract] [Full Text] [Related]

  • 30. Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.
    Lau SS, Monks TJ, Everitt JI, Kleymenova E, Walker CL.
    Chem Res Toxicol; 2001 Jan 20; 14(1):25-33. PubMed ID: 11170505
    [Abstract] [Full Text] [Related]

  • 31. Biallelic mutations of the Tsc2 gene in chemically induced rat renal cell carcinoma.
    Satake N, Urakami S, Hirayama Y, Izumi K, Hino O.
    Int J Cancer; 1998 Sep 11; 77(6):895-900. PubMed ID: 9714060
    [Abstract] [Full Text] [Related]

  • 32. Multistep renal carcinogenesis in the Eker (Tsc 2 gene mutant) rat model.
    Hino O.
    Curr Mol Med; 2004 Dec 11; 4(8):807-11. PubMed ID: 15579027
    [Abstract] [Full Text] [Related]

  • 33.
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    [No Abstract] [Full Text] [Related]

  • 34. Mapping and determination of the cDNA sequence of the Erc gene preferentially expressed in renal cell carcinoma in the Tsc2 gene mutant (Eker) rat model.
    Yamashita Y, Yokoyama M, Kobayashi E, Takai S, Hino O.
    Biochem Biophys Res Commun; 2000 Aug 18; 275(1):134-40. PubMed ID: 10944454
    [Abstract] [Full Text] [Related]

  • 35. Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development.
    Rennebeck G, Kleymenova EV, Anderson R, Yeung RS, Artzt K, Walker CL.
    Proc Natl Acad Sci U S A; 1998 Dec 22; 95(26):15629-34. PubMed ID: 9861021
    [Abstract] [Full Text] [Related]

  • 36. Use of the spontaneous Tsc2 knockout (Eker) rat model of hereditary renal cell carcinoma for the study of renal carcinogens.
    McDorman KS, Wolf DC.
    Toxicol Pathol; 2002 Dec 22; 30(6):675-80. PubMed ID: 12512868
    [Abstract] [Full Text] [Related]

  • 37. Metabolic abnormalities induced by mitochondrial dysfunction in skeletal muscle of the renal carcinoma Eker (TSC2+/-) rat model.
    Aizawa Y, Shirai T, Kobayashi T, Hino O, Tsujii Y, Inoue H, Kazami M, Tadokoro T, Suzuki T, Kobayashi K, Yamamoto Y.
    Biosci Biotechnol Biochem; 2016 Aug 22; 80(8):1513-9. PubMed ID: 27031579
    [Abstract] [Full Text] [Related]

  • 38. Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model.
    Sahin K, Cross B, Sahin N, Ciccone K, Suleiman S, Osunkoya AO, Master V, Harris W, Carthon B, Mohammad R, Bilir B, Wertz K, Moreno CS, Walker CL, Kucuk O.
    Arch Biochem Biophys; 2015 Apr 15; 572():36-39. PubMed ID: 25602702
    [Abstract] [Full Text] [Related]

  • 39. Morphology of cerebral lesions in the Eker rat model of tuberous sclerosis.
    Wenzel HJ, Patel LS, Robbins CA, Emmi A, Yeung RS, Schwartzkroin PA.
    Acta Neuropathol; 2004 Aug 15; 108(2):97-108. PubMed ID: 15185103
    [Abstract] [Full Text] [Related]

  • 40. The tuberous sclerosis complex model Eker (TSC2+/-) rat exhibits hyperglycemia and hyperketonemia due to decreased glycolysis in the liver.
    Aizawa Y, Shirai T, Kobayashi T, Hino O, Tsujii Y, Inoue H, Kazami M, Tadokoro T, Suzuki T, Kobayashi KI, Yamamoto Y.
    Arch Biochem Biophys; 2016 Jan 15; 590():48-55. PubMed ID: 26550928
    [Abstract] [Full Text] [Related]

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