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190 related items for PubMed ID: 9780228
1. The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. Motamedi H, Shafiee A. Eur J Biochem; 1998 Sep 15; 256(3):528-34. PubMed ID: 9780228 [Abstract] [Full Text] [Related]
2. The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units. Wu K, Chung L, Revill WP, Katz L, Reeves CD. Gene; 2000 Jun 13; 251(1):81-90. PubMed ID: 10863099 [Abstract] [Full Text] [Related]
3. Structural organization of a multifunctional polyketide synthase involved in the biosynthesis of the macrolide immunosuppressant FK506. Motamedi H, Cai SJ, Shafiee A, Elliston KO. Eur J Biochem; 1997 Feb 15; 244(1):74-80. PubMed ID: 9063448 [Abstract] [Full Text] [Related]
4. Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme. Gatto GJ, McLoughlin SM, Kelleher NL, Walsh CT. Biochemistry; 2005 Apr 26; 44(16):5993-6002. PubMed ID: 15835888 [Abstract] [Full Text] [Related]
5. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei. Tang L, Yoon YJ, Choi CY, Hutchinson CR. Gene; 1998 Aug 31; 216(2):255-65. PubMed ID: 9729415 [Abstract] [Full Text] [Related]
6. Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis: analysis of enzymatic domains in four polyketide synthases. Ikeda H, Nonomiya T, Omura S. J Ind Microbiol Biotechnol; 2001 Sep 31; 27(3):170-6. PubMed ID: 11780788 [Abstract] [Full Text] [Related]
7. Origin of the allyl group in FK506 biosynthesis. Goranovic D, Kosec G, Mrak P, Fujs S, Horvat J, Kuscer E, Kopitar G, Petkovic H. J Biol Chem; 2010 May 07; 285(19):14292-300. PubMed ID: 20194504 [Abstract] [Full Text] [Related]
8. Biosynthesis of ansatrienin (mycotrienin) and naphthomycin. Identification and analysis of two separate biosynthetic gene clusters in Streptomyces collinus Tü 1892. Chen S, von Bamberg D, Hale V, Breuer M, Hardt B, Müller R, Floss HG, Reynolds KA, Leistner E. Eur J Biochem; 1999 Apr 07; 261(1):98-107. PubMed ID: 10103039 [Abstract] [Full Text] [Related]
9. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity. Florova G, Kazanina G, Reynolds KA. Biochemistry; 2002 Aug 20; 41(33):10462-71. PubMed ID: 12173933 [Abstract] [Full Text] [Related]
10. Characterization of methyltransferase and hydroxylase genes involved in the biosynthesis of the immunosuppressants FK506 and FK520. Motamedi H, Shafiee A, Cai SJ, Streicher SL, Arison BH, Miller RR. J Bacteriol; 1996 Sep 20; 178(17):5243-8. PubMed ID: 8752344 [Abstract] [Full Text] [Related]
11. The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes. Aparicio JF, Colina AJ, Ceballos E, Martín JF. J Biol Chem; 1999 Apr 09; 274(15):10133-9. PubMed ID: 10187796 [Abstract] [Full Text] [Related]
12. Mechanisms of molecular recognition in the pikromycin polyketide synthase. Chen S, Xue Y, Sherman DH, Reynolds KA. Chem Biol; 2000 Dec 09; 7(12):907-18. PubMed ID: 11137814 [Abstract] [Full Text] [Related]
13. The product of dpsC confers starter unit fidelity upon the daunorubicin polyketide synthase of Streptomyces sp. strain C5. Rajgarhia VB, Priestley ND, Strohl WR. Metab Eng; 2001 Jan 09; 3(1):49-63. PubMed ID: 11162232 [Abstract] [Full Text] [Related]
14. Streptomyces chrysomallus FKBP-33 is a novel immunophilin consisting of two FK506 binding domains; its gene is transcriptionally coupled to the FKBP-12 gene. Pahl A, Keller U. EMBO J; 1994 Aug 01; 13(15):3472-80. PubMed ID: 8062824 [Abstract] [Full Text] [Related]
15. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues. Mo S, Kim DH, Lee JH, Park JW, Basnet DB, Ban YH, Yoo YJ, Chen SW, Park SR, Choi EA, Kim E, Jin YY, Lee SK, Park JY, Liu Y, Lee MO, Lee KS, Kim SJ, Kim D, Park BC, Lee SG, Kwon HJ, Suh JW, Moore BS, Lim SK, Yoon YJ. J Am Chem Soc; 2011 Feb 02; 133(4):976-85. PubMed ID: 21175203 [Abstract] [Full Text] [Related]
16. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity. Tang Y, Lee TS, Kobayashi S, Khosla C. Biochemistry; 2003 Jun 03; 42(21):6588-95. PubMed ID: 12767243 [Abstract] [Full Text] [Related]
17. Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. Ikeda H, Nonomiya T, Usami M, Ohta T, Omura S. Proc Natl Acad Sci U S A; 1999 Aug 17; 96(17):9509-14. PubMed ID: 10449723 [Abstract] [Full Text] [Related]
18. Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering. Lechner A, Wilson MC, Ban YH, Hwang JY, Yoon YJ, Moore BS. ACS Synth Biol; 2013 Jul 19; 2(7):379-83. PubMed ID: 23654255 [Abstract] [Full Text] [Related]
19. A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain. Ruan X, Stassi D, Lax SA, Katz L. Gene; 1997 Dec 05; 203(1):1-9. PubMed ID: 9426000 [Abstract] [Full Text] [Related]
20. Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis. Blažič M, Kosec G, Baebler Š, Gruden K, Petković H. Microb Cell Fact; 2015 Oct 14; 14():164. PubMed ID: 26466669 [Abstract] [Full Text] [Related] Page: [Next] [New Search]