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317 related items for PubMed ID: 9788613

  • 1. Glutathione-dependent biotransformation of the alkylating drug thiotepa and transport of its metabolite monoglutathionylthiotepa in human MCF-7 breast cancer cells.
    Cnubben NH, Rommens AJ, Oudshoorn MJ, Van Bladeren PJ.
    Cancer Res; 1998 Oct 15; 58(20):4616-23. PubMed ID: 9788613
    [Abstract] [Full Text] [Related]

  • 2. The role of human glutathione S-transferase isoenzymes in the formation of glutathione conjugates of the alkylating cytostatic drug thiotepa.
    Dirven HA, Dictus EL, Broeders NL, van Ommen B, van Bladeren PJ.
    Cancer Res; 1995 Apr 15; 55(8):1701-6. PubMed ID: 7712478
    [Abstract] [Full Text] [Related]

  • 3. Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1.
    Diah SK, Smitherman PK, Townsend AJ, Morrow CS.
    Toxicol Appl Pharmacol; 1999 Jun 01; 157(2):85-93. PubMed ID: 10366541
    [Abstract] [Full Text] [Related]

  • 4. Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa.
    Srivastava SK, Singhal SS, Hu X, Awasthi YC, Zimniak P, Singh SV.
    Arch Biochem Biophys; 1999 Jun 01; 366(1):89-94. PubMed ID: 10334868
    [Abstract] [Full Text] [Related]

  • 5. Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
    Dirven HA, van Ommen B, van Bladeren PJ.
    Cancer Res; 1994 Dec 01; 54(23):6215-20. PubMed ID: 7954469
    [Abstract] [Full Text] [Related]

  • 6. Interactions of glutathione S-transferase-pi with ethacrynic acid and its glutathione conjugate.
    Awasthi S, Srivastava SK, Ahmad F, Ahmad H, Ansari GA.
    Biochim Biophys Acta; 1993 Jul 10; 1164(2):173-8. PubMed ID: 8329448
    [Abstract] [Full Text] [Related]

  • 7. Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance.
    Harbottle A, Daly AK, Atherton K, Campbell FC.
    Int J Cancer; 2001 Jun 15; 92(6):777-83. PubMed ID: 11351295
    [Abstract] [Full Text] [Related]

  • 8. Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicity.
    Paumi CM, Ledford BG, Smitherman PK, Townsend AJ, Morrow CS.
    J Biol Chem; 2001 Mar 16; 276(11):7952-6. PubMed ID: 11115505
    [Abstract] [Full Text] [Related]

  • 9. Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells.
    Chen G, Waxman DJ.
    Biochem Pharmacol; 1994 Mar 15; 47(6):1079-87. PubMed ID: 8147907
    [Abstract] [Full Text] [Related]

  • 10. Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments.
    Vaidya SS, Walsh SW, Gerk PM.
    Mol Pharm; 2009 Mar 15; 6(6):1689-702. PubMed ID: 19397308
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1.
    Yao J, Chang M, Li Y, Pisha E, Liu X, Yao D, Elguindi EC, Blond SY, Bolton JL.
    Chem Res Toxicol; 2002 Jul 15; 15(7):935-42. PubMed ID: 12119004
    [Abstract] [Full Text] [Related]

  • 12. Expression of human mu or alpha class glutathione S-transferases in stably transfected human MCF-7 breast cancer cells: effect on cellular sensitivity to cytotoxic agents.
    Townsend AJ, Tu CP, Cowan KH.
    Mol Pharmacol; 1992 Feb 15; 41(2):230-6. PubMed ID: 1538704
    [Abstract] [Full Text] [Related]

  • 13. Protection by transfected glutathione S-transferase isozymes against carcinogen-induced alkylation of cellular macromolecules in human MCF-7 cells.
    Fields WR, Li Y, Townsend AJ.
    Carcinogenesis; 1994 Jun 15; 15(6):1155-60. PubMed ID: 8020149
    [Abstract] [Full Text] [Related]

  • 14. Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.
    Geroni C, Marchini S, Cozzi P, Galliera E, Ragg E, Colombo T, Battaglia R, Howard M, D'Incalci M, Broggini M.
    Cancer Res; 2002 Apr 15; 62(8):2332-6. PubMed ID: 11956092
    [Abstract] [Full Text] [Related]

  • 15. Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity.
    Smitherman PK, Townsend AJ, Kute TE, Morrow CS.
    J Pharmacol Exp Ther; 2004 Jan 15; 308(1):260-7. PubMed ID: 14569069
    [Abstract] [Full Text] [Related]

  • 16. Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells.
    Chen G, Waxman DJ.
    Biochem Pharmacol; 1995 May 26; 49(11):1691-701. PubMed ID: 7786310
    [Abstract] [Full Text] [Related]

  • 17. Carbamoylation of glutathione reductase by N,N-bis(2-chloroethyl)-N- nitrosourea associated with inhibition of multidrug resistance protein (MRP) function.
    Vanhoefer U, Yin MB, Harstrick A, Seeber S, Rustum YM.
    Biochem Pharmacol; 1997 Mar 21; 53(6):801-9. PubMed ID: 9113101
    [Abstract] [Full Text] [Related]

  • 18. Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid.
    O'Dwyer PJ, LaCreta F, Nash S, Tinsley PW, Schilder R, Clapper ML, Tew KD, Panting L, Litwin S, Comis RL.
    Cancer Res; 1991 Nov 15; 51(22):6059-65. PubMed ID: 1933869
    [Abstract] [Full Text] [Related]

  • 19. Mitomycin C sensitivity in human bladder cancer cells: possible role of glutathione and glutathione transferase in resistance.
    Xu BH, Gupta V, Singh SV.
    Arch Biochem Biophys; 1994 Jan 15; 308(1):164-70. PubMed ID: 8311448
    [Abstract] [Full Text] [Related]

  • 20. Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases.
    Dirven HA, Megens L, Oudshoorn MJ, Dingemanse MA, van Ommen B, van Bladeren PJ.
    Chem Res Toxicol; 1995 Jan 15; 8(7):979-86. PubMed ID: 8555414
    [Abstract] [Full Text] [Related]

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