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Journal Abstract Search

159 related items for PubMed ID: 9790897

  • 21. Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; evidence for structure in the urea unfolded state.
    Tew DJ, Bottomley SP.
    J Mol Biol; 2001 Nov 09; 313(5):1161-9. PubMed ID: 11700071
    [Abstract] [Full Text] [Related]

  • 22. Serpin polymerization and its role in disease--the molecular basis of alpha1-antitrypsin deficiency.
    Knaupp AS, Bottomley SP.
    IUBMB Life; 2009 Jan 09; 61(1):1-5. PubMed ID: 18785256
    [Abstract] [Full Text] [Related]

  • 23. Structural change in β-sheet A of Z α(1)-antitrypsin is responsible for accelerated polymerization and disease.
    Knaupp AS, Bottomley SP.
    J Mol Biol; 2011 Nov 04; 413(4):888-98. PubMed ID: 21945526
    [Abstract] [Full Text] [Related]

  • 24. Characterising the association of latency with α(1)-antitrypsin polymerisation using a novel monoclonal antibody.
    Tan L, Perez J, Mela M, Miranda E, Burling KA, Rouhani FN, DeMeo DL, Haq I, Irving JA, Ordóñez A, Dickens JA, Brantly M, Marciniak SJ, Alexander GJ, Gooptu B, Lomas DA.
    Int J Biochem Cell Biol; 2015 Jan 04; 58():81-91. PubMed ID: 25462157
    [Abstract] [Full Text] [Related]

  • 25. A kinetic mechanism for the polymerization of alpha1-antitrypsin.
    Dafforn TR, Mahadeva R, Elliott PR, Sivasothy P, Lomas DA.
    J Biol Chem; 1999 Apr 02; 274(14):9548-55. PubMed ID: 10092640
    [Abstract] [Full Text] [Related]

  • 26. Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
    Crowther DC, Belorgey D, Miranda E, Kinghorn KJ, Sharp LK, Lomas DA.
    Eur J Hum Genet; 2004 Mar 02; 12(3):167-72. PubMed ID: 14694355
    [Abstract] [Full Text] [Related]

  • 27. Role of Lys335 in the metastability and function of inhibitory serpins.
    Im H, Yu MH.
    Protein Sci; 2000 May 02; 9(5):934-41. PubMed ID: 10850803
    [Abstract] [Full Text] [Related]

  • 28. Bypassing the kinetic trap of serpin protein folding by loop extension.
    Im H, Ahn HY, Yu MH.
    Protein Sci; 2000 Aug 02; 9(8):1497-502. PubMed ID: 10975571
    [Abstract] [Full Text] [Related]

  • 29. 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.
    Mahadeva R, Dafforn TR, Carrell RW, Lomas DA.
    J Biol Chem; 2002 Mar 01; 277(9):6771-4. PubMed ID: 11773044
    [Abstract] [Full Text] [Related]

  • 30. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC, Skinner R, Carrell RW, Lesk AM.
    J Mol Biol; 2000 Jan 21; 295(3):651-65. PubMed ID: 10623554
    [Abstract] [Full Text] [Related]

  • 31. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC, Skinner R, Carrell RW, Lesk AM.
    J Mol Biol; 2000 Feb 18; 296(2):685-99. PubMed ID: 10669617
    [Abstract] [Full Text] [Related]

  • 32. Computer modelling of human alpha 1-antitrypsin reactive site loop behaviour under mild conditions.
    Kołoczek H, Jezierski G, Pasenkiewicz-Gierula M.
    Acta Biochim Pol; 1996 Feb 18; 43(3):467-74. PubMed ID: 8922028
    [Abstract] [Full Text] [Related]

  • 33. A structural basis for loop C-sheet polymerization in serpins.
    Zhang Q, Law RH, Bottomley SP, Whisstock JC, Buckle AM.
    J Mol Biol; 2008 Mar 07; 376(5):1348-59. PubMed ID: 18234218
    [Abstract] [Full Text] [Related]

  • 34. Alpha1-antitrypsin deficiency. 4: Molecular pathophysiology.
    Lomas DA, Parfrey H.
    Thorax; 2004 Jun 07; 59(6):529-35. PubMed ID: 15170041
    [Abstract] [Full Text] [Related]

  • 35. Defining the mechanism of polymerization in the serpinopathies.
    Ekeowa UI, Freeke J, Miranda E, Gooptu B, Bush MF, Pérez J, Teckman J, Robinson CV, Lomas DA.
    Proc Natl Acad Sci U S A; 2010 Oct 05; 107(40):17146-51. PubMed ID: 20855577
    [Abstract] [Full Text] [Related]

  • 36. Alpha1-antitrypsin deficiency--a model for conformational diseases.
    Carrell RW, Lomas DA.
    N Engl J Med; 2002 Jan 03; 346(1):45-53. PubMed ID: 11778003
    [No Abstract] [Full Text] [Related]

  • 37. alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization.
    Lomas DA, Elliott PR, Sidhar SK, Foreman RC, Finch JT, Cox DW, Whisstock JC, Carrell RW.
    J Biol Chem; 1995 Jul 14; 270(28):16864-70. PubMed ID: 7622502
    [Abstract] [Full Text] [Related]

  • 38. Molecular pathogenesis of liver disease in alpha1-antitrypsin deficiency.
    Teckman JH, Qu D, Perlmutter DH.
    Hepatology; 1996 Dec 14; 24(6):1504-16. PubMed ID: 8938188
    [No Abstract] [Full Text] [Related]

  • 39. Acid Denaturation of alpha1-antitrypsin: characterization of a novel mechanism of serpin polymerization.
    Devlin GL, Chow MK, Howlett GJ, Bottomley SP.
    J Mol Biol; 2002 Dec 06; 324(4):859-70. PubMed ID: 12460583
    [Abstract] [Full Text] [Related]

  • 40. Conformational changes in serpins and the mechanism of alpha 1-antitrypsin deficiency.
    Carrell RW, Whisstock J, Lomas DA.
    Am J Respir Crit Care Med; 1994 Dec 06; 150(6 Pt 2):S171-5. PubMed ID: 7952655
    [Abstract] [Full Text] [Related]

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